This is a groundbreaking study for pericyte fans. We discovered the unique pericyte marker Higd1b which only labels pericytes without any off-target effect from other mural cells.
#Pericyte #PulmonaryHypertension
1/2
A subpopulation of Higd1b+ lung capillary pericytes
👉Migrate to distal arteriole
👉Upregulate Vimentin
👉Acquire #SmoothMuscleCell identity (α-SMA, circumferential wrapping)
in🐭Hypoxic PH
#SciArt
Ke Yuan lab @embojournal.org 2025
www.embopress.org/doi/full/10....
1/2
A subpopulation of Higd1b+ lung capillary pericytes
👉Migrate to distal arteriole
👉Upregulate Vimentin
👉Acquire #SmoothMuscleCell identity (α-SMA, circumferential wrapping)
in🐭Hypoxic PH
#SciArt
Ke Yuan lab @embojournal.org 2025
www.embopress.org/doi/full/10....
January 27, 2025 at 8:26 PM
This is a groundbreaking study for pericyte fans. We discovered the unique pericyte marker Higd1b which only labels pericytes without any off-target effect from other mural cells.