Keavney Lab
@keavneylab.bsky.social
Lab group led by Prof Bernard Keavney focussing on cardiovascular genomics, big data & congenital heart disease in the @uom-bhfcre.bsky.social 🫀🧬
Posts by group members
🌐 https://www.keavneylab.com
📍 Manchester, UK
Posts by group members
🌐 https://www.keavneylab.com
📍 Manchester, UK
Pinned
Keavney Lab
@keavneylab.bsky.social
· Nov 27
We're a lab group based at the University of Manchester in the Division of Cardiovascular Sciences & BHF Centre of Research Excellence led by Prof Bernard Keavney
Our research focuses on the genetics of congenital heart disease & inherited cardiac conditions using functional & bioinformatic methods
Our research focuses on the genetics of congenital heart disease & inherited cardiac conditions using functional & bioinformatic methods
Great talk today from our postdoc Yingjuan at the DCVS monthly seminar 🫀
June 5, 2025 at 4:33 PM
Great talk today from our postdoc Yingjuan at the DCVS monthly seminar 🫀
Reposted by Keavney Lab
We have some exciting opportunities for aspiring researchers! Fully funded BHF studentships in interdisciplinary cardiovascular research. Deadline to apply is 6th June
#PhD #studentships
www.bmh.manchester.ac.uk/study/resear...
#PhD #studentships
www.bmh.manchester.ac.uk/study/resear...
British Heart Foundation Centre of Research Excellence Studentships
Find out more about the British Heart Foundation Centre of Research Excellence Studentships available for cardiovascular research.
www.bmh.manchester.ac.uk
May 13, 2025 at 9:34 AM
We have some exciting opportunities for aspiring researchers! Fully funded BHF studentships in interdisciplinary cardiovascular research. Deadline to apply is 6th June
#PhD #studentships
www.bmh.manchester.ac.uk/study/resear...
#PhD #studentships
www.bmh.manchester.ac.uk/study/resear...
Reposted by Keavney Lab
Through out February and March, we organised a range of activities as part of a fundraising competition between the BHF Centres for Research Excellence and recipients of Accelerator Awards, which included 8 Universities. Ultimately, we raised a total of £3144! Here's a summary of what we got up to
April 16, 2025 at 8:03 AM
Through out February and March, we organised a range of activities as part of a fundraising competition between the BHF Centres for Research Excellence and recipients of Accelerator Awards, which included 8 Universities. Ultimately, we raised a total of £3144! Here's a summary of what we got up to
Reposted by Keavney Lab
Since this account is new we'll start with some catch-ups about what's been going on over a busy couple of months in the CRE - starting with our official launch on 27th February at the Whitworth Art Gallery 🧵
April 2, 2025 at 2:36 PM
Since this account is new we'll start with some catch-ups about what's been going on over a busy couple of months in the CRE - starting with our official launch on 27th February at the Whitworth Art Gallery 🧵
Reposted by Keavney Lab
Last chance to donate to our go red fundraiser! Our researchers have been working hard all month raising money
www.justgiving.com/page/uombhfcre
www.justgiving.com/page/uombhfcre
March 31, 2025 at 5:03 PM
Last chance to donate to our go red fundraiser! Our researchers have been working hard all month raising money
www.justgiving.com/page/uombhfcre
www.justgiving.com/page/uombhfcre
Reposted by Keavney Lab
Fantastic turnout at our bake sale today! Raised £700 and counting. This was our last event in a series raising money for @thebhf.bsky.social and today has taken us over £3000!
To find out more about our cause and donate visit www.justgiving.com/page/uombhfcre
To find out more about our cause and donate visit www.justgiving.com/page/uombhfcre
March 28, 2025 at 4:11 PM
Fantastic turnout at our bake sale today! Raised £700 and counting. This was our last event in a series raising money for @thebhf.bsky.social and today has taken us over £3000!
To find out more about our cause and donate visit www.justgiving.com/page/uombhfcre
To find out more about our cause and donate visit www.justgiving.com/page/uombhfcre
Reposted by Keavney Lab
The Manchester BHF CRE advances cardiovascular research by driving interdisciplinary collaboration across 5 themes
We focus on innovative strategies for prevention, diagnosis, treatment & care - combining cutting-edge technology & clinical expertise
See more at www.bhf-cre.manchester.ac.uk
We focus on innovative strategies for prevention, diagnosis, treatment & care - combining cutting-edge technology & clinical expertise
See more at www.bhf-cre.manchester.ac.uk
March 28, 2025 at 4:15 PM
The Manchester BHF CRE advances cardiovascular research by driving interdisciplinary collaboration across 5 themes
We focus on innovative strategies for prevention, diagnosis, treatment & care - combining cutting-edge technology & clinical expertise
See more at www.bhf-cre.manchester.ac.uk
We focus on innovative strategies for prevention, diagnosis, treatment & care - combining cutting-edge technology & clinical expertise
See more at www.bhf-cre.manchester.ac.uk
Congrats to our PhD students Claudia & @tachycardio.bsky.social who both passed their first year vivas yesterday 🎉
March 21, 2025 at 6:13 PM
Congrats to our PhD students Claudia & @tachycardio.bsky.social who both passed their first year vivas yesterday 🎉
‼️ New review from PhD student Claudia on 15q11.2 (BP1-BP2) microdeletion
BP1-BP2 del causes a syndrome including developmental delays and anatomical malformations including congenital heart disease. Variable expressivity and low penetrance make genetic counselling a challenge
#MedSky #CardioSky 🧪
BP1-BP2 del causes a syndrome including developmental delays and anatomical malformations including congenital heart disease. Variable expressivity and low penetrance make genetic counselling a challenge
#MedSky #CardioSky 🧪
Frontiers | Congenital heart disease presentations in the 15q11.2 microdeletion syndrome
www.frontiersin.org
March 19, 2025 at 5:30 PM
‼️ New review from PhD student Claudia on 15q11.2 (BP1-BP2) microdeletion
BP1-BP2 del causes a syndrome including developmental delays and anatomical malformations including congenital heart disease. Variable expressivity and low penetrance make genetic counselling a challenge
#MedSky #CardioSky 🧪
BP1-BP2 del causes a syndrome including developmental delays and anatomical malformations including congenital heart disease. Variable expressivity and low penetrance make genetic counselling a challenge
#MedSky #CardioSky 🧪
Reposted by Keavney Lab
The University of Manchester has launched the @thebhf.bsky.social Manchester Centre of Research Excellence following an award of £4 million to support world-class cardiovascular disease from the leading charity.
www.manchester.ac.uk/about/news/b...
www.manchester.ac.uk/about/news/b...
British Heart Foundation’s Centre of Research Excellence launches at The University of Manchester
The University of Manchester has launched the British Heart Foundation (BHF) Manchester Centre of Research Excellence following an award of £4 million to support world-class cardiovascular disease fro...
www.manchester.ac.uk
February 27, 2025 at 3:24 PM
The University of Manchester has launched the @thebhf.bsky.social Manchester Centre of Research Excellence following an award of £4 million to support world-class cardiovascular disease from the leading charity.
www.manchester.ac.uk/about/news/b...
www.manchester.ac.uk/about/news/b...
A fantastic day last week celebrating the launch of the BHF Manchester Centre of Research Excellence. Excited for all the work to come over the next 5 years
@thebhf.bsky.social @fbmh-uom.bsky.social
@thebhf.bsky.social @fbmh-uom.bsky.social
March 3, 2025 at 2:46 PM
A fantastic day last week celebrating the launch of the BHF Manchester Centre of Research Excellence. Excited for all the work to come over the next 5 years
@thebhf.bsky.social @fbmh-uom.bsky.social
@thebhf.bsky.social @fbmh-uom.bsky.social
26 researchers from the Manchester BHF Centre of Research Excellence - including our own @tachycardio.bsky.social & Yingjuan Liu - are aiming to cover 2000 miles by foot this month to raise money for @thebhf.bsky.social 🚶🏃
Donations would be greatly appreciated ❤️
www.justgiving.com/page/uombhfcre
Donations would be greatly appreciated ❤️
www.justgiving.com/page/uombhfcre
Manchester BHF CRE Heart Month Fundraising
Help Manchester BHF CRE raise money to support British Heart Foundation
www.justgiving.com
February 24, 2025 at 2:02 PM
26 researchers from the Manchester BHF Centre of Research Excellence - including our own @tachycardio.bsky.social & Yingjuan Liu - are aiming to cover 2000 miles by foot this month to raise money for @thebhf.bsky.social 🚶🏃
Donations would be greatly appreciated ❤️
www.justgiving.com/page/uombhfcre
Donations would be greatly appreciated ❤️
www.justgiving.com/page/uombhfcre
Reposted by Keavney Lab
New review out today in Open Biology, a Royal Society publication on mitochondria-ER contacts and their potential use as therapeutic targets. doi.org/10.1098/rsob... @keavneylab.bsky.social @thebhf.bsky.social @official-uom.bsky.social @gensocuk.bsky.social
The fundamental role of mitochondria–endoplasmic reticulum contacts in ageing and declining healthspan | Open Biology
This open question research article highlights mitochondria-associated endoplasmic
reticulum (ER) membranes (MAMs), which have emerged as crucial cellular structures
that challenge our traditional und...
doi.org
February 12, 2025 at 9:24 AM
New review out today in Open Biology, a Royal Society publication on mitochondria-ER contacts and their potential use as therapeutic targets. doi.org/10.1098/rsob... @keavneylab.bsky.social @thebhf.bsky.social @official-uom.bsky.social @gensocuk.bsky.social
Reposted by Keavney Lab
Most cardiac arrests happen at home, and knowing CPR could save the life of someone you love. All you need is your phone and a cushion to learn CPR in just 15 minutes, for free with RevivR. Be ready for when it matters most. ❤️ Find out more about RevivR here: bit.ly/3E7D0fg:
February 7, 2025 at 9:10 AM
Most cardiac arrests happen at home, and knowing CPR could save the life of someone you love. All you need is your phone and a cushion to learn CPR in just 15 minutes, for free with RevivR. Be ready for when it matters most. ❤️ Find out more about RevivR here: bit.ly/3E7D0fg:
Great day at the @uomresearchit.bsky.social UK Biobank showcase today including a brilliant talk from our PhD student @tachycardio.bsky.social!
January 30, 2025 at 3:38 PM
Great day at the @uomresearchit.bsky.social UK Biobank showcase today including a brilliant talk from our PhD student @tachycardio.bsky.social!
Reposted by Keavney Lab
Looking forward to day 2 of @fogenomics.bsky.social
I'm finding Bluesky a great place to discuss #genomics Here is a starter pack for anyone looking for related accounts to follow. Let me know if you want adding or if have any suggestions! #FOG2025
go.bsky.app/FpcXQK7
I'm finding Bluesky a great place to discuss #genomics Here is a starter pack for anyone looking for related accounts to follow. Let me know if you want adding or if have any suggestions! #FOG2025
go.bsky.app/FpcXQK7
January 30, 2025 at 9:47 AM
Looking forward to day 2 of @fogenomics.bsky.social
I'm finding Bluesky a great place to discuss #genomics Here is a starter pack for anyone looking for related accounts to follow. Let me know if you want adding or if have any suggestions! #FOG2025
go.bsky.app/FpcXQK7
I'm finding Bluesky a great place to discuss #genomics Here is a starter pack for anyone looking for related accounts to follow. Let me know if you want adding or if have any suggestions! #FOG2025
go.bsky.app/FpcXQK7
Reposted by Keavney Lab
Packed house for Prof Martin Rutter, Deputy Chief Scientist @ukbiobank.bsky.social - the first talk of the UoM UK Biobank user group showcase. If you're a UoM researcher using the database, get involved! bit.ly/cadirUKB
January 30, 2025 at 1:24 PM
Packed house for Prof Martin Rutter, Deputy Chief Scientist @ukbiobank.bsky.social - the first talk of the UoM UK Biobank user group showcase. If you're a UoM researcher using the database, get involved! bit.ly/cadirUKB
New paper from our collaborators in the school of Engineering & University of Cape Town #academicsky 🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation - Scientific Reports
Scientific Reports - An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation
www.nature.com
January 22, 2025 at 3:34 PM
New paper from our collaborators in the school of Engineering & University of Cape Town #academicsky 🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Merry Christmas from the Keavney lab 🎄
December 19, 2024 at 5:52 PM
Merry Christmas from the Keavney lab 🎄
Reposted by Keavney Lab
📦 Here’s a starter pack for @official-uom.bsky.social University of Manchester staff and departments.
💬 Reply if you wish to be added
go.bsky.app/pDWEN6
💬 Reply if you wish to be added
go.bsky.app/pDWEN6
December 10, 2024 at 11:10 AM
📦 Here’s a starter pack for @official-uom.bsky.social University of Manchester staff and departments.
💬 Reply if you wish to be added
go.bsky.app/pDWEN6
💬 Reply if you wish to be added
go.bsky.app/pDWEN6
🎓 Funded PhD opportunites
We have two #UoM200 bicenntenial PhD projects available in the group. Open to students worldwide & based at Uni of Manchester, UK. Deadline 10th Jan
More info on the projects below ⬇️
#AcademicSky 🧬💻🧪🫀
We have two #UoM200 bicenntenial PhD projects available in the group. Open to students worldwide & based at Uni of Manchester, UK. Deadline 10th Jan
More info on the projects below ⬇️
#AcademicSky 🧬💻🧪🫀
December 3, 2024 at 2:00 PM
🎓 Funded PhD opportunites
We have two #UoM200 bicenntenial PhD projects available in the group. Open to students worldwide & based at Uni of Manchester, UK. Deadline 10th Jan
More info on the projects below ⬇️
#AcademicSky 🧬💻🧪🫀
We have two #UoM200 bicenntenial PhD projects available in the group. Open to students worldwide & based at Uni of Manchester, UK. Deadline 10th Jan
More info on the projects below ⬇️
#AcademicSky 🧬💻🧪🫀
Reposted by Keavney Lab
🎓 Funded PhD opportunity
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
www.findaphd.com
November 28, 2024 at 5:08 PM
🎓 Funded PhD opportunity
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
🎓 Funded PhD opportunity
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
www.findaphd.com
November 28, 2024 at 5:08 PM
🎓 Funded PhD opportunity
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
Computational project studying the co-morbidities of congenital heart disease in large datasets using AI & machine learning
Open to students worldwide - based at Uni of Manchester, UK
www.findaphd.com/phds/project...
#AcademicSky #UoM200 🧬💻
We showed that vaccination significantly decreased COVID-19 related hospitalisation & mortality in congenital heart disease patients, but even post-vaccine they have a higher risk of severe outcomes. Made possible by @thebhf.bsky.social Data Science Centre
heart.bmj.com/content/110/... 🧬💻🫀
heart.bmj.com/content/110/... 🧬💻🫀
November 28, 2024 at 3:23 PM
We showed that vaccination significantly decreased COVID-19 related hospitalisation & mortality in congenital heart disease patients, but even post-vaccine they have a higher risk of severe outcomes. Made possible by @thebhf.bsky.social Data Science Centre
heart.bmj.com/content/110/... 🧬💻🫀
heart.bmj.com/content/110/... 🧬💻🫀
Delighted that we were able to contribute to this paper
New paper out in EJHG making new diagnoses and identifying candidate disease genes in individuals with congenital heart disease t.co/9A4IFSABzU - fab collaboration to be a part of - led by Verity Hartill using data from the 100,000 Genomes Project
https://rdcu.be/d1rI4
t.co
November 27, 2024 at 3:41 PM
Delighted that we were able to contribute to this paper