Kausar Raza
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kausarraza.bsky.social
Kausar Raza
@kausarraza.bsky.social
160 followers 370 following 10 posts
Assistant Professor@UWL| Eberly Fellow@psu_chemistry: Fe-S clusters| Postdoc @Caltech: DNA Signalling Ph.D. @IISc: in vitro_in vivo_Chemo-PDT| Metals_in Medicine_Biology
#chembio #bioinorg
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kausarraza.bsky.social
I’m pleased to share that my highlight article has just appeared in @ChemBioChem @wiley.com
Five‐In‐One Antibacterial Strategy: A Mn(I) Complex Lights Up the Fight Against Tuberculosis
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#metals_in_medicine #infectiousdiseases #PDT
Five‐In‐One Antibacterial Strategy: A Mn(I) Complex Lights Up the Fight Against Tuberculosis
A light-activated Mn(I) complex combats tuberculosis (TB) through a five-in-one antibacterial strategy, releasing carbon monoxide (CO), generating reactive oxygen species, disrupting membranes, formi....
chemistry-europe.onlinelibrary.wiley.com
September 29, 2025 at 11:16 PM
kausarraza.bsky.social
Our latest review highlights the potential of mitochondria-targeted vanadium complexes in #photodynamic therapy for cancer, ROS generation & DNA crosslinking for targeted treatments @ChemBioChem. #BioinorganicChemistry #VanadiumComplexes #PDT
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Vanadium Complexes for Mitochondria‐Targeted Photodynamic Therapy
This highlight covers recent advances in mitochondria-targeted vanadium complexes for photodynamic therapy (PDT) in cancer treatment. These complexes demonstrate selective in vitro cytotoxicity towar...
chemistry-europe.onlinelibrary.wiley.com
January 29, 2025 at 2:26 AM
kausarraza.bsky.social
And the last one on ‘Role of Iron-Sulfur Cluster in the Zinc-binding domain of the SARS-CoV-2 Helicase.’
www.pnas.org/doi/10.1073/...
#bioinorganic #metals_in_medicine #metals_in_biology #covid-19 #FeS_cluster
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
November 24, 2024 at 2:57 AM
kausarraza.bsky.social
Another from my postdoc work on [Fe-S] clusters in DNA charge transport and enzymatic signaling.
pubs.acs.org/doi/10.1021/...
#bioinorganic #metals_in_biology
@amerchemsociety.bsky.social @caltechcce.bsky.social
Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase
DNA synthesis during replication begins with the generation of an ∼10-nucleotide primer by DNA primase. Primase contains a redox-active 4Fe-4S cluster in the C-terminal domain of the p58 subunit (p58C...
pubs.acs.org
November 24, 2024 at 2:48 AM
kausarraza.bsky.social
Finally here on BlueSky! Sharing one of my earlier research works pubs.acs.org/doi/10.1021/..., a step into understanding mito-targeting Pt-BODIPY in PDT.
Looking forward to engaging with this amazing community!
#ChemSky #bioinorganic #metals_in_medicine
Pyriplatin-Boron-Dipyrromethene Conjugates for Imaging and Mitochondria-Targeted Photodynamic Therapy
Monofunctional pyriplatin analogues cis-[Pt(NH3)2(L)Cl](NO3) (1–3) having boron-dipyrromethene (BODIPY) pendants (L) with 1,3,5,7-tetramethyl-8-(4-pyridyl)-4,4′-difluoroboradiazaindacene moieties were...
pubs.acs.org
November 24, 2024 at 2:38 AM