💫 Practical advice for intraventricular meds (Part 5):
Flush with PF saline? Sure. But what if it’s not compatible with your drug, like amphotericin B? Simple—just flush with the CSF you definitely took out before giving the drug (right?). Who needs saline when you got the good stuff? Problem solved

💫 Practical advice for intraventricular meds (Part 4):
🐌 How slow can you go? Administer drug slowly over a couple minutes. Drug should be prepared in smallest size syringe 💉 that can hold the drug volume—>helps provider better control the admin rate = less pressure and gentler administration

💫 Practical advice for interventricular Meds (Part 3):
Volume of CSF removed prior to administration = drug volume. In the cranial vault, small volumes can have big impact especially when ICPs are of concern. In this case, every drop really does count 💧⚖️💧

#neurocrit #pharmsky

💫 Part 2:
Best to keep intraventricular meds < 2-3 mL/dose, ideally. Preservatives? No thanks! 👎 They can cause ADEs in the 🧠 Some are probably safer than others, but until we get better data, the rule of thumb is to avoid them in intraventricular meds and use preservative-free flush 💦

Yes! 👍

I’m so jealous 😟 🎁