Katie Hardman
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katiehardman.bsky.social
Katie Hardman
@katiehardman.bsky.social
Postdoc in the Breeze and Muench groups @AstburyCentre.bsky.social @UniversityofLeeds.bsky.social
Reposted by Katie Hardman
Take a look at our new paper! We show that YbiO can achieve a conductance equivalent to MscL, the largest known gated ion channel. We also show the presence of several subconducting states. One state is consistent with a structure we determine using cryoEM.

www.cell.com/structure/fu...
The mechanosensitive channel YbiO has a conductance equivalent to the largest gated-pore
Lane et al. demonstrate that the mechanosensitive channel YbiO can achieve conductances equivalent to the largest gated-pore in nature when subjected to membrane tension. Single-channel analysis shows...
www.cell.com
February 15, 2025 at 12:42 PM