Katie Marlow
@katiegmarlow.bsky.social
Genetics PhD Student at UAB 🧬 Su Lab
Auburn University Alum
#tRNA. #Nanopore. #aging.
Auburn University Alum
#tRNA. #Nanopore. #aging.
Reposted by Katie Marlow
New manuscript from the Novoa lab was published this week in Genome Biology! You can give it a read here: rdcu.be/ebiIs
February 28, 2025 at 4:18 PM
New manuscript from the Novoa lab was published this week in Genome Biology! You can give it a read here: rdcu.be/ebiIs
Reposted by Katie Marlow
Very happy to share our updated #Nano3P-seq protocol, adapted to #nanopore R10 chemistry. After a lot of troubleshooting both in the wet lab protocol but also the computational analysis pipeline, we finally made it! :-) www.biorxiv.org/content/10.1...
Nano3P-seq: charting the coding and non-coding transcriptome at single molecule resolution
RNA polyadenylation is crucial for RNA maturation, stability and function, with polyA tail lengths significantly influencing mRNA translation, efficiency and decay. Here, we provide a step-by-step pro...
www.biorxiv.org
November 21, 2024 at 3:05 PM
Very happy to share our updated #Nano3P-seq protocol, adapted to #nanopore R10 chemistry. After a lot of troubleshooting both in the wet lab protocol but also the computational analysis pipeline, we finally made it! :-) www.biorxiv.org/content/10.1...
Reposted by Katie Marlow
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
Reposted by Katie Marlow
Best practices for germline variant and DNA methylation analysis of second- and third-generation sequencing data. #VariantAnalysis #Epigenetics #ShortRead #LongRead #Sequencing #Genomics #Bioinformatics #BestPractices #HumanGenomics 🧬🖥️
humgenomics.biomedcentral.com/articles/10....
humgenomics.biomedcentral.com/articles/10....
Best practices for germline variant and DNA methylation analysis of second- and third-generation sequencing data - Human Genomics
This comprehensive review provides insights and suggested strategies for the analysis of germline variants using second- and third-generation sequencing technologies (SGS and TGS). It addresses the cr...
humgenomics.biomedcentral.com
November 22, 2024 at 5:06 PM
Best practices for germline variant and DNA methylation analysis of second- and third-generation sequencing data. #VariantAnalysis #Epigenetics #ShortRead #LongRead #Sequencing #Genomics #Bioinformatics #BestPractices #HumanGenomics 🧬🖥️
humgenomics.biomedcentral.com/articles/10....
humgenomics.biomedcentral.com/articles/10....
Reposted by Katie Marlow
Very excited to dig into the paper - tool & methodology the authors developed could save lots of headaches for my current sequencing project.
Can anyone reach the linked GitHub URL on the published article though? Entire NanoConsensus repo seems to 404 on my end. 🖥️🧬
www.nature.com/articles/s41...
Can anyone reach the linked GitHub URL on the published article though? Entire NanoConsensus repo seems to 404 on my end. 🖥️🧬
www.nature.com/articles/s41...
Native RNA nanopore sequencing reveals antibiotic-induced loss of rRNA modifications in the A- and P-sites - Nature Communications
It remains unclear whether rRNA modifications can be naturally altered in response to antibiotics in bacteria. Here, the authors analyzed direct RNA nanopore sequencing data with an analytical pipelin...
www.nature.com
November 29, 2024 at 10:55 AM
Very excited to dig into the paper - tool & methodology the authors developed could save lots of headaches for my current sequencing project.
Can anyone reach the linked GitHub URL on the published article though? Entire NanoConsensus repo seems to 404 on my end. 🖥️🧬
www.nature.com/articles/s41...
Can anyone reach the linked GitHub URL on the published article though? Entire NanoConsensus repo seems to 404 on my end. 🖥️🧬
www.nature.com/articles/s41...
Reposted by Katie Marlow
First paper of our lab today @natureportfolio.bsky.social by Nussi!
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
December 4, 2024 at 8:53 PM
First paper of our lab today @natureportfolio.bsky.social by Nussi!
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
Reposted by Katie Marlow
👀 Working on a #StarterPack for early career researchers (PhD students & Postdocs) in #genomics & #bioinformatics 🧬🖥️ Please share! Happy to add those working in this area so please suggest. Seeing a lot of PIs on here but would love to see more students 🎓🚀
November 20, 2024 at 3:38 PM
👀 Working on a #StarterPack for early career researchers (PhD students & Postdocs) in #genomics & #bioinformatics 🧬🖥️ Please share! Happy to add those working in this area so please suggest. Seeing a lot of PIs on here but would love to see more students 🎓🚀