Merci Léa 😘

Thank you so much Charles! 🤗

Thanks a lot Hyeonmin!! 🙏😊

Merci Baptiste 🙏😊

Thanks a lot for your kind words 🙏😊

Merci, my dear ❤️😊

10/ A huge THANK YOU to all co-authors for the amazing team effort! We are grateful for our funders @erc.europa.eu MSCA @dfg.de @agencerecherche.bsky.social

9/ Altogether our work demonstrates that ERS clade transcription factors have been acting as the transcriptional link between the CSP and the infectosome since the most recent common ancestor of land plants.

8/ Next, we investigated the link of ERS to other members of the CSP. We hypothesized that ERS act downstream of CYCLOPS.

We could show that ERS are induced by CYCLOPs in transactivation assays in N. bethamiana. @tatiana-vernie.bsky.social

7/ We hypothesized that ERS induce the so-called "infectosome" that includes LIN and is required for the formation of symbiosis-specific intracellular structures in angiosperms.

We could confirm an induction of LIN by ERS in transactivation assays in N. bethamiana @tatiana-vernie.bsky.social

6/ Thus, we named these transcription factors "Ethylene response factor required for symbiosis" (ERS).

We then asked how ERS are regulating different types of endosymbioses?

5/ We then generated double mutants of two paralogs of these TFs in #MyMarchantia and investigated their function during AMS.

We found that the double mutants were completely deficient in AMS - similarly to other members of the common symbiosis pathway (CSP; see also Vernie et al 2025, PNAS).

4/ To functionally dissect conserved gene modules, we then cross-referenced RNAseq data from C. fissa during ErM and #MyMarchantia during arbuscular mycorrhizal symbiosis (AMS).

We found a group of ethylene response transcription factors that were upregulated during both types of endosymbioses.

3/ We aimed to understand how different types of intracellular symbioses diversified during land plant evolution.

Initially, @leocastanedo.bsky.social, studied Ericoid mycorrhizae (ErM) in the leafy liverwort Calypogeia fissa

2/ Together with @leocastanedo.bsky.social @tatiana-vernie.bsky.social @kellerjeanphd.bsky.social @mbianc.bsky.social @pierremarcdelaux.bsky.social and many others @lrsv-toulouse.bsky.social