We got an opportunity to discuss the role of sleep, diet and exercise in maintaining mental health and preventing neurodegenerative disorders, such as Alzheimer’s disease.

Josie Pittiglio-Vivona
Christiane Wrann

Moustafa Algamal, Rebecca Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia Kastanenka.

Special thanks to our support teams at The National Institutes of Health, Japan Society for the Promotion of Science, Japan Agency for Medical Research and Development.

Many thanks to the Mass General Brigham Research team for highlighting this research!

Authors: Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown-Harding, Linda Liang, Alex Lovely,

Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka*. We are also deeply grateful for the support from the Japan Society for the Promotion of Science and the National Institutes of Health.
@mgbresearch.bsky.social

A huge thank you to all co-authors who made this possible: Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown-Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang,

This work provides proof-of-concept for stem-cell therapy to repair cortical networks in Alzheimer’s disease. Link to the paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...

Featuring Matthew Rowan, Brianne Kent, Rashad Hussain, and Bryce Mander.

Don’t miss this deep dive into the neural and glymphatic systems shaping the future of Alzheimer’s research.

Sleep isn’t just rest! It’s a window into brain’s health.

This session will explore how sleep impairments contribute to memory loss and Alzheimer’s pathology. The session will highlight mechanistic and translational insights into preserving cognitive function and reducing neuropathology.

Supported by NervGen Pharma
Virtual poster: cattendee.abstractsonline.com/meeting/2117...

On Tuesday, you can meet with Dr. Sema Aygar, and discuss her exciting work. This study reveals ISP helps neurons stay healthy and reduces Aβ levels. Sema encourages anyone to come check out the poster (LBP089) anytime during the session from 8:00AM to 12:00PM.

Our findings show that stem cell therapy restores sleep-dependent brain rhythms impaired in Alzheimer’s disease, offering a promising therapeutic strategy.

Looking forward to connecting with you all and exchanging ideas! See you there!

I look forward to insightful conversation with the esteemed Ciaran Murphy-Royal, Ph.D., Mayuko Arai, and Brianne Kent.
Special thanks to Dr. W Haung (Ho) Yu for organizing this symposium.

On Monday, you can meet with Md. Joynal Abedin, and discuss his exciting work. This study reveals compartment-specific disruptions of astrocytic calcium activity in an Alzheimer's mouse model. He encourages anyone to come check out his poster anytime during the session from 8AM to 12PM.