Dave Kammeyer
@kammeyer.org
CEO mentality.ai. We build AI, computer vision, and high reliability learned systems for our customers. Glider pilot, amateur philosopher.
PCR can’t amplify RNA that’s not on the swab, and you need ~300 copies to work reliably. The question is will there be adequate RNA in the nose if replication is inhibited in the nose. Not saying I have the answer, it’s a question.
September 10, 2025 at 10:12 PM
PCR can’t amplify RNA that’s not on the swab, and you need ~300 copies to work reliably. The question is will there be adequate RNA in the nose if replication is inhibited in the nose. Not saying I have the answer, it’s a question.
My understanding of the protocol is that normally they only did a PCR if there was an antigen +. They also did PCR on everyone at the end. I'd expect all antigen+ to be PCR+. Do you think if the virus is replicating in the lungs but inhibited in the nose that this doesn't affect PCR performance?
September 10, 2025 at 9:30 PM
My understanding of the protocol is that normally they only did a PCR if there was an antigen +. They also did PCR on everyone at the end. I'd expect all antigen+ to be PCR+. Do you think if the virus is replicating in the lungs but inhibited in the nose that this doesn't affect PCR performance?
My question when I saw that paper was how much of the effect is azelastine just interfering with the test? I.e. if we grant that azelastine inhibits, what if you get COVID and then squirt some up your nose, and then later swab your nose, will the inhibition make the test go negative?
September 10, 2025 at 8:41 PM
My question when I saw that paper was how much of the effect is azelastine just interfering with the test? I.e. if we grant that azelastine inhibits, what if you get COVID and then squirt some up your nose, and then later swab your nose, will the inhibition make the test go negative?
Yeah this sounds awesome!
March 9, 2025 at 5:37 AM
Yeah this sounds awesome!
Scientifically proven: www.theatlantic.com/magazine/arc...
Nutrition Science’s Most Preposterous Result: Could Ice Cream Possibly Be Good for You?
Studies show a mysterious health benefit to ice cream. Scientists don’t want to talk about it.
www.theatlantic.com
November 18, 2024 at 6:08 PM
Scientifically proven: www.theatlantic.com/magazine/arc...