Jason Wong
@jwhwong.bsky.social
Professor at the School of Biomedical Sciences, University of Hong Kong. Uses genomics data to understand DNA repair and cancer.
Now out at #jbiolchem www.sciencedirect.com/science/arti...
May 28, 2025 at 2:52 PM
Now out at #jbiolchem www.sciencedirect.com/science/arti...
Reposted by Jason Wong
Our full-day mini AI hackathon on genomic language models starts soon: 8.30am-8.30pm! With a whole team, we aim to test how gLMs work for two tasks:
1. SNP2GEX: personal variants to gene expression (unseen individuals & genes);
2. Seq2CellxTF: short regulatory to TF binding (unseen cell & TFs).
1. SNP2GEX: personal variants to gene expression (unseen individuals & genes);
2. Seq2CellxTF: short regulatory to TF binding (unseen cell & TFs).
April 2, 2025 at 12:22 AM
Our full-day mini AI hackathon on genomic language models starts soon: 8.30am-8.30pm! With a whole team, we aim to test how gLMs work for two tasks:
1. SNP2GEX: personal variants to gene expression (unseen individuals & genes);
2. Seq2CellxTF: short regulatory to TF binding (unseen cell & TFs).
1. SNP2GEX: personal variants to gene expression (unseen individuals & genes);
2. Seq2CellxTF: short regulatory to TF binding (unseen cell & TFs).
Great to finally see LocusMasterTE in print by PhD student, Sojung Lee. We developed a bioinformatics method to leverage long read sequencing data to improve expression quantification of transposable elements genomebiology.biomedcentral.com/articles/10.... #GenomeBiology
LocusMasterTE: integrating long-read RNA sequencing improves locus-specific quantification of transposable element expression - Genome Biology
Transposable elements (TEs) can influence human diseases by disrupting genome integrity, yet their quantification has been challenging due to the repetitive nature of these sequences across the genome...
genomebiology.biomedcentral.com
March 27, 2025 at 4:21 AM
Great to finally see LocusMasterTE in print by PhD student, Sojung Lee. We developed a bioinformatics method to leverage long read sequencing data to improve expression quantification of transposable elements genomebiology.biomedcentral.com/articles/10.... #GenomeBiology
First post on Bluesky 🦋. Happy to share some new work on the epigenetic regulation of a human endogenous retrovirus (HERV) in cancer. @biorxivpreprint.bsky.social bsky.app/profile/bior... 🧵 (1/n)
A tumor necrosis factor-α responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7 https://www.biorxiv.org/content/10.1101/2025.03.09.642286v1
March 17, 2025 at 6:36 AM
First post on Bluesky 🦋. Happy to share some new work on the epigenetic regulation of a human endogenous retrovirus (HERV) in cancer. @biorxivpreprint.bsky.social bsky.app/profile/bior... 🧵 (1/n)