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We found strong conservation of the ARF DNA-binding residues and most variation leads to loss of function. B3 domains from different plant lineages were able to functionally complement MpARF1, showing that DNA-binding is strongly conserved across evolution.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
A conserved ARF–DNA interface underlies auxin-triggered transcriptional response | PNAS
Auxin Response Factor (ARF) plant transcription factors are the key effectors in auxin
signaling. Their DNA-Binding Domain (DBD) contains a B3 doma...
www.pnas.org
April 2, 2025 at 11:46 AM
We found strong conservation of the ARF DNA-binding residues and most variation leads to loss of function. B3 domains from different plant lineages were able to functionally complement MpARF1, showing that DNA-binding is strongly conserved across evolution.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...