@julienbryois.bsky.social
Senior scientist leveraging human genetics and single cell genomics for drug discovery
Reposted
First time on Bsky and first big announcement!
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
Estimation and mapping of the missing heritability of human phenotypes - Nature
WGS data were used from 347,630 individuals with European ancestry in the UK Biobank to obtain high-precision estimates of coding and non-coding rare variant heritability for 34 co...
www.nature.com
November 12, 2025 at 5:57 PM
First time on Bsky and first big announcement!
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
Reposted
Proud that the third GWAS for Alzheimer's dementia from the PGC-ALZ working group was just posted online! Huge amounts of work, and what a great collaboration! Check out our exciting findings below 👇 @pgcgenetics.bsky.social #ctglab #alzheimer #dementia #GWAS
🚨 The preprint for our GWAS of Alzheimer’s disease (AD) is out
Preprint: medrxiv.org/content/10.1...
🧵
Preprint: medrxiv.org/content/10.1...
🧵
Genomic analyses reveal new insights into Alzheimer's disease
Alzheimer's disease (AD) is the most common cause of dementia, with global case numbers projected to reach 153 million in 2050. AD is highly heritable, with twin-based heritability estimates of 60-80%...
medrxiv.org
October 14, 2025 at 7:24 AM
Proud that the third GWAS for Alzheimer's dementia from the PGC-ALZ working group was just posted online! Huge amounts of work, and what a great collaboration! Check out our exciting findings below 👇 @pgcgenetics.bsky.social #ctglab #alzheimer #dementia #GWAS
Reposted
I made a bot that posts pre-prints of single cell papers:
@prepub-singlecell.bsky.social
(I posted about it a little while ago when no one was here, so posting again now :D)
It's pretty dumb so very open to suggestions for improvements!
@prepub-singlecell.bsky.social
(I posted about it a little while ago when no one was here, so posting again now :D)
It's pretty dumb so very open to suggestions for improvements!
November 14, 2024 at 6:52 AM
I made a bot that posts pre-prints of single cell papers:
@prepub-singlecell.bsky.social
(I posted about it a little while ago when no one was here, so posting again now :D)
It's pretty dumb so very open to suggestions for improvements!
@prepub-singlecell.bsky.social
(I posted about it a little while ago when no one was here, so posting again now :D)
It's pretty dumb so very open to suggestions for improvements!
Reposted
Over the past week or so there's been a flurry of papers based on one big dataset from the Roussos lab.
Great to see single nuclei datasets of the brain with really meaningful numbers of donors!
Great to see single nuclei datasets of the brain with really meaningful numbers of donors!
November 8, 2024 at 9:18 AM
Over the past week or so there's been a flurry of papers based on one big dataset from the Roussos lab.
Great to see single nuclei datasets of the brain with really meaningful numbers of donors!
Great to see single nuclei datasets of the brain with really meaningful numbers of donors!