3/5 We show that the genes repressed and activated by DOT1L are in distinct chromatin environments: repressed genes are in H3k27me3+ regions while activated genes are in H3k27ac+/H3k79me2+ regions. Interestingly many DOT1L-activated genes in spermatids are on the X chromosome...
January 29, 2025 at 8:29 AM
3/5 We show that the genes repressed and activated by DOT1L are in distinct chromatin environments: repressed genes are in H3k27me3+ regions while activated genes are in H3k27ac+/H3k79me2+ regions. Interestingly many DOT1L-activated genes in spermatids are on the X chromosome...
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January 17, 2025 at 3:34 PM
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