Julia Vorhauser
juliavorhauser.bsky.social
Julia Vorhauser
@juliavorhauser.bsky.social
Postdoc in the Wredenberg lab at Karolinska Institute. Interested in redox biology and metabolism :D
Reposted by Julia Vorhauser
„Man kann sich mit dem Nationalsozialismus geistig nicht auseinander-setzen, weil er ungeistig ist."
Alexander Schmorell, Mitbegründer der Widerstandsgruppe Weiße Rose, Verfasser bekannter Flugblätter der Gruppe, wurde am 16 September 1917 geboren.
Guten Morgen
September 16, 2025 at 5:28 AM
Reposted by Julia Vorhauser
The findings highlight a new way of thinking about how cell growth is controlled – one that could eventually be harnessed to improve cancer treatment ⤵️
Subtle chemical tweak helps determine whether cells grow, potentially affecting cancer risk
Subtle chemical tweak helps determine whether cells grow, potentially affecting cancer risk
www.icr.ac.uk
August 27, 2025 at 9:23 AM
I am very happy to share that my PhD work in the Mansfeld lab (www.mansfeldlab.com) was published yesterday! 🎉 In this study, we characterized a novel redox switch on p21 that regulates proliferation: www.cell.com/molecular-ce...
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk
A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision
ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al. show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine 41 (C41) during the G2 phase contro...
www.cell.com
August 26, 2025 at 7:18 AM
Reposted by Julia Vorhauser
New research from Steve Cutty and @alexisbarr.bsky.social published in the British Journal of Cancer shows the protein p21 promotes survival in lung cancer cells strengthening the rationale for targeting p21 as a cancer treatment. This work was also funded by @cancerresearchuk.org
Blocking the cell cycle inhibitor p21 prevents regrowth in lung cancer cells
Blocking the activity of a protein called p21 stops lung cancer cells entering a ‘sleep-like’ state that allows them to survive chemotherapy. Blocking p21 causes more cancer cells to die and reduces t...
lms.mrc.ac.uk
January 3, 2025 at 11:33 AM