Julia Beets
@juliabeets.bsky.social
PhD Student | FlyCADD | Genetic variation in life-history adaptation in Drosophila melanogaster | Single nucleotide polymorphisms | @ALIFE_VU VU Amsterdam
With @geneticjulia.bsky.social @bernardkim.bsky.social @jellers.bsky.social Katja Hoedjes, Mirte Bosse
March 7, 2025 at 2:18 PM
With @geneticjulia.bsky.social @bernardkim.bsky.social @jellers.bsky.social Katja Hoedjes, Mirte Bosse
FlyCADD was developed by applying the CADD framework (Kircher et al. 2014) for the first time to an insect genome, using available genome annotations for D. melanogaster and a drosophilid whole genome alignment.
All FlyCADD impact prediction scores are available on Zenodo!
All FlyCADD impact prediction scores are available on Zenodo!
March 7, 2025 at 2:17 PM
FlyCADD was developed by applying the CADD framework (Kircher et al. 2014) for the first time to an insect genome, using available genome annotations for D. melanogaster and a drosophilid whole genome alignment.
All FlyCADD impact prediction scores are available on Zenodo!
All FlyCADD impact prediction scores are available on Zenodo!
FlyCADD provides impact prediction scores for any SNP on the D. melanogaster genome! We show FlyCADDs abilities in:
- ranking candidate SNPs (from GWAS/E&R) for variant prioritization
- interpretation of naturally occuring SNPs
- refining of CRISPR-Cas9 experimental design
- ranking candidate SNPs (from GWAS/E&R) for variant prioritization
- interpretation of naturally occuring SNPs
- refining of CRISPR-Cas9 experimental design
March 7, 2025 at 2:17 PM
FlyCADD provides impact prediction scores for any SNP on the D. melanogaster genome! We show FlyCADDs abilities in:
- ranking candidate SNPs (from GWAS/E&R) for variant prioritization
- interpretation of naturally occuring SNPs
- refining of CRISPR-Cas9 experimental design
- ranking candidate SNPs (from GWAS/E&R) for variant prioritization
- interpretation of naturally occuring SNPs
- refining of CRISPR-Cas9 experimental design