Jesper Svejstrup
@jsvejstrup.bsky.social
Professor@UCPH, interested in transcription, DNA, RNA, DNA repair, gene expression, ubiquitin cellular stress, damage signaling, European Research Council + life in the lab from the Svejstrup lab at University of Copenhagen
I'm very happy to share this review, written with Dan Blears, on a new interpretation of promoter-proximal pausing in the context of a transcription checkpoint. We're not the only ones with these ideas, but they've not been sufficiently explored the way we do here: genesdev.cshlp.org/content/earl...
Transcription quality control at the promoter-proximal checkpoint
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
September 26, 2025 at 12:32 PM
I'm very happy to share this review, written with Dan Blears, on a new interpretation of promoter-proximal pausing in the context of a transcription checkpoint. We're not the only ones with these ideas, but they've not been sufficiently explored the way we do here: genesdev.cshlp.org/content/earl...
Extremely proud to share the impressive work done by Anouk Olthof et al. on how cells maintain healthy levels of RNAPII, and how they respond when levels are too low. Fascinating stuff, we think www.biorxiv.org/content/10.1...
Systems-level feedback loops maintain gene expression homeostasis following RNA polymerase II dosage perturbation
Transcription is regulated by sequence-specific transcription factors and enzymes allowing access to genes in chromatin. However, recent data indicate that the abundance of RNA polymerase II (RNAPII) ...
www.biorxiv.org
September 19, 2025 at 10:55 AM
Extremely proud to share the impressive work done by Anouk Olthof et al. on how cells maintain healthy levels of RNAPII, and how they respond when levels are too low. Fascinating stuff, we think www.biorxiv.org/content/10.1...
Excited to share our latest paper, now online in Molecular Cell. First, it shows that the RNAPII-CTD kinases CDK9 and CDK12 are Ser5-Ser2 kinases. Secondly, it describes the activation mechanism of CDK12/13 by PAF1C complex. Congratulations to David López Martínez and coauthors!
lnkd.in/d_nbfMht
lnkd.in/d_nbfMht
LinkedIn
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lnkd.in
May 3, 2025 at 11:17 AM
Excited to share our latest paper, now online in Molecular Cell. First, it shows that the RNAPII-CTD kinases CDK9 and CDK12 are Ser5-Ser2 kinases. Secondly, it describes the activation mechanism of CDK12/13 by PAF1C complex. Congratulations to David López Martínez and coauthors!
lnkd.in/d_nbfMht
lnkd.in/d_nbfMht
Reposted by Jesper Svejstrup
Danes offer to buy California to spite Trump’s Greenland aims: ‘We’ll bring hygge to Hollywood’
Danes offer to buy California to spite Trump’s Greenland aims: ‘We’ll bring hygge to Hollywood’
Satirical petition from Denmark, which owns Greenland, racks up 200,000 signatures as Trump eyes Arctic island
Since returning to the presidency last month, Donald Trump has called for Canada to become the 51st US state, suggested he might take over the…
www.theguardian.com
February 11, 2025 at 8:57 PM
Danes offer to buy California to spite Trump’s Greenland aims: ‘We’ll bring hygge to Hollywood’
Looking for 2 or more highly motivated PhD students to join our quest to understand the interplay between gene expression, genome instability, and human disease
jobportal.ku.dk/phd/?show=16...
Deadline: March 6, 2025
Please share
jobportal.ku.dk/phd/?show=16...
Deadline: March 6, 2025
Please share
PhD fellowships at the Center for Gene Expression
jobportal.ku.dk
February 13, 2025 at 5:54 PM
Looking for 2 or more highly motivated PhD students to join our quest to understand the interplay between gene expression, genome instability, and human disease
jobportal.ku.dk/phd/?show=16...
Deadline: March 6, 2025
Please share
jobportal.ku.dk/phd/?show=16...
Deadline: March 6, 2025
Please share
Setting up shop in advance of closing our profile on X.
February 13, 2025 at 4:16 PM
Setting up shop in advance of closing our profile on X.