js
@jspaul2003.bsky.social
i like computers and cells!
caltech cs + bio double major ‘25. current stanford chemE phd.
caltech cs + bio double major ‘25. current stanford chemE phd.
Reposted by js
The machine-guided humanization paper is out after peer review! doi.org/10.1016/j.ce... Key contributions from current and previous international students on visas, representing 5+ countries.
June 3, 2025 at 5:26 PM
The machine-guided humanization paper is out after peer review! doi.org/10.1016/j.ce... Key contributions from current and previous international students on visas, representing 5+ countries.
Reposted by js
So we beat on. Gene/cell therapies would benefit many patients, but often use proteins that could be recognized as non-self by our immune system and cause problems. We combine algorithms to build proteins that are therapeutically relevant and can masquerade as our own parts doi.org/10.1101/2025...
Machine-Guided Dual-Objective Protein Engineering for Deimmunization and Therapeutic Functions
Cell and gene therapies often rely on the expression of exogenous proteins derived from nonhuman organisms. An emerging consensus is to reduce the potential immunogenicity of such therapies by instead...
doi.org
March 1, 2025 at 4:09 AM
So we beat on. Gene/cell therapies would benefit many patients, but often use proteins that could be recognized as non-self by our immune system and cause problems. We combine algorithms to build proteins that are therapeutically relevant and can masquerade as our own parts doi.org/10.1101/2025...