Joshua Pajak
@joshuapajak.bsky.social
American Cancer Society Postdoctoral fellow and structural biologist in the @briankelch.bsky.social lab at UMass Chan Medical school. I study ATPases and DNA replication/repair. Phage and MD simulations were my first scientific love. he/him/his
2. We dramatically reworked both text and the figure explaining the setup and results from our MANT-ATP assay for improved clarity.
Thanks again to everyone involved in this project, and to the anonymous reviewers whose critique strengthened the final manuscript!
Onto the next one!
Thanks again to everyone involved in this project, and to the anonymous reviewers whose critique strengthened the final manuscript!
Onto the next one!
November 13, 2025 at 7:13 PM
2. We dramatically reworked both text and the figure explaining the setup and results from our MANT-ATP assay for improved clarity.
Thanks again to everyone involved in this project, and to the anonymous reviewers whose critique strengthened the final manuscript!
Onto the next one!
Thanks again to everyone involved in this project, and to the anonymous reviewers whose critique strengthened the final manuscript!
Onto the next one!
1. We now include a mutual information based analysis of our molecular dynamics data to predict how RFC subunits sense and respond to ATP hydrolysis. We highlight the "sensor II" arginine as a hub of allosteric communication.
November 13, 2025 at 7:13 PM
1. We now include a mutual information based analysis of our molecular dynamics data to predict how RFC subunits sense and respond to ATP hydrolysis. We highlight the "sensor II" arginine as a hub of allosteric communication.
I met Prof. McIntosh at the American Cancer Society Jilers conference in Nov of last year. He was so incredibly kind to all the trainees and talked with all of us at our posters (particularly those of us doing basic science). He had a knack for telling stories. Can't wait to read his perspective :)
October 16, 2025 at 11:46 AM
I met Prof. McIntosh at the American Cancer Society Jilers conference in Nov of last year. He was so incredibly kind to all the trainees and talked with all of us at our posters (particularly those of us doing basic science). He had a knack for telling stories. Can't wait to read his perspective :)