Joshua Kaste
@joshuakaste.bsky.social
Postdoctoral researcher. Working on metabolic modeling of plant systems to identify engineering targets for improved food security and sustainability. He/him
Reposted by Joshua Kaste
New Article: "Metabolic flux analysis in leaf metabolism quantifies the link between photorespiration and one carbon metabolism" rdcu.be/eDWLH
C flux quantification between two major plant metabolisms—photorespiration and C1 metabolism—using 13CO2 labelling and...
C flux quantification between two major plant metabolisms—photorespiration and C1 metabolism—using 13CO2 labelling and...
September 3, 2025 at 3:54 PM
New Article: "Metabolic flux analysis in leaf metabolism quantifies the link between photorespiration and one carbon metabolism" rdcu.be/eDWLH
C flux quantification between two major plant metabolisms—photorespiration and C1 metabolism—using 13CO2 labelling and...
C flux quantification between two major plant metabolisms—photorespiration and C1 metabolism—using 13CO2 labelling and...
New flux mapping study out in Nature Plants (doi.org/10.1038/s414...), led by Kelem Gashu, that puts some numbers on the connection between photorespiration and one carbon metabolism. I had the privilege of helping out with some of the modeling and statistics in the study.
Metabolic flux analysis in leaf metabolism quantifies the link between photorespiration and one carbon metabolism - Nature Plants
This paper quantified carbon flux between two major plant metabolisms—photorespiration and C1 metabolism—using 13CO2 labelling and isotopically non-stationary metabolic flux analysis.
doi.org
September 3, 2025 at 5:13 PM
New flux mapping study out in Nature Plants (doi.org/10.1038/s414...), led by Kelem Gashu, that puts some numbers on the connection between photorespiration and one carbon metabolism. I had the privilege of helping out with some of the modeling and statistics in the study.
Hi - I’m looking for roles inside and outside of academia in Canada, and would appreciate any leads or contacts y’all may have. I’m a computational and molecular biologist with a broad range of prior experience in both wet lab and dry lab work. If you or someone you know is hiring, get in touch!
May 10, 2025 at 8:02 PM
Hi - I’m looking for roles inside and outside of academia in Canada, and would appreciate any leads or contacts y’all may have. I’m a computational and molecular biologist with a broad range of prior experience in both wet lab and dry lab work. If you or someone you know is hiring, get in touch!
New article that I played a small part in, headed up by Yuan Xu, now out in Scientific Reports: doi.org/10.1038/s415.... Yuan gathered some great labeling data in Camelina sativa under high light and high CO2 conditions and compared the INST-MFA estimated central carbon fluxes to control conditions
The effects of photosynthetic rate on respiration in light, starch/sucrose partitioning, and other metabolic fluxes within photosynthesis - Scientific Reports
Scientific Reports - The effects of photosynthetic rate on respiration in light, starch/sucrose partitioning, and other metabolic fluxes within photosynthesis
doi.org
March 11, 2025 at 3:36 PM
New article that I played a small part in, headed up by Yuan Xu, now out in Scientific Reports: doi.org/10.1038/s415.... Yuan gathered some great labeling data in Camelina sativa under high light and high CO2 conditions and compared the INST-MFA estimated central carbon fluxes to control conditions
Nice article about work I collaborated on in MSU's Plant Research Laboratory newsletter: prl.natsci.msu.edu/news-and-eve...
MSU researchers glean photosynthetic insights from volcanic hot springs
Expanding knowledge of the carbon concentrating mechanism in the extremophilic algae C. merolae allows scientists to better understand and possibly improve photosynthesis.
prl.natsci.msu.edu
February 7, 2025 at 5:21 PM
Nice article about work I collaborated on in MSU's Plant Research Laboratory newsletter: prl.natsci.msu.edu/news-and-eve...
🚨Preprint alert🚨We present models of real and hypothetical maize symbioses (with AMF and rhizobia, respectively) individually and in tandem to assess the costs-and-benefits of these to maize growth. Check it out here: www.biorxiv.org/content/10.1...
Metabolic modeling reveals synergistic growth benefits of engineering maize symbiosis with rhizobia and arbuscular mycorrhizal fungi
Engineering N2-fixing rhizobia symbiosis in cereals and enhancing association with arbuscular mycorrhizal fungi (AMF) are two strategies being pursued to improve agricultural sustainability. However, ...
www.biorxiv.org
February 2, 2025 at 4:52 PM
🚨Preprint alert🚨We present models of real and hypothetical maize symbioses (with AMF and rhizobia, respectively) individually and in tandem to assess the costs-and-benefits of these to maize growth. Check it out here: www.biorxiv.org/content/10.1...
Reposted by Joshua Kaste
www.nature.com/articles/s41...
They "identified many highly conserved positions that tolerate mutation and rare mutations that improve CO2 affinity. These data indicate that non-trivial biochemical changes are readily accessible"
#PlantScience
They "identified many highly conserved positions that tolerate mutation and rare mutations that improve CO2 affinity. These data indicate that non-trivial biochemical changes are readily accessible"
#PlantScience
A map of the rubisco biochemical landscape - Nature
A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible, signposting further e...
www.nature.com
January 24, 2025 at 11:56 AM
www.nature.com/articles/s41...
They "identified many highly conserved positions that tolerate mutation and rare mutations that improve CO2 affinity. These data indicate that non-trivial biochemical changes are readily accessible"
#PlantScience
They "identified many highly conserved positions that tolerate mutation and rare mutations that improve CO2 affinity. These data indicate that non-trivial biochemical changes are readily accessible"
#PlantScience
Very nice 'news & views' write-up about the C. merolae modeling work @anne-steensma.bsky.social, me, and our wonderful co-authors presented in Plant Phys: doi.org/10.1093/plph...
Metabolic modeling suggested non-canonical algal carbon concentrating mechanism in Cyanidioschyzon merolae
Maneesh Lingwan; Metabolic modeling suggested non-canonical algal carbon concentrating mechanism in Cyanidioschyzon merolae, Plant Physiology, , kiaf019, h
doi.org
January 20, 2025 at 5:00 PM
Very nice 'news & views' write-up about the C. merolae modeling work @anne-steensma.bsky.social, me, and our wonderful co-authors presented in Plant Phys: doi.org/10.1093/plph...
Reposted by Joshua Kaste
New paper alert 😎🔔🚨. We present a standardized protocol for the polyextremophile Cyanidioschizon merolae 🦠 transformation🧬! Together with our team at ASU AzCATI🇺🇸, and Uni Northern BC 🇨🇦 #openaccess #algae #Biotechnology
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
December 7, 2024 at 3:36 AM
New paper alert 😎🔔🚨. We present a standardized protocol for the polyextremophile Cyanidioschizon merolae 🦠 transformation🧬! Together with our team at ASU AzCATI🇺🇸, and Uni Northern BC 🇨🇦 #openaccess #algae #Biotechnology
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
How do you effectively photosynthesize in hell (figuratively speaking)? See our new article, just published in Plant Physiology: doi.org/10.1093/plph...
doi.org
December 5, 2024 at 5:13 PM
How do you effectively photosynthesize in hell (figuratively speaking)? See our new article, just published in Plant Physiology: doi.org/10.1093/plph...
Reposted by Joshua Kaste
A starter pack for scientists involved in developing computational algorithms, software, models, and tools to advance #plantscience.
Let me know in the comments or DM if you'd like to be added.
go.bsky.app/KcVXefi
Let me know in the comments or DM if you'd like to be added.
go.bsky.app/KcVXefi
November 20, 2024 at 5:18 PM
A starter pack for scientists involved in developing computational algorithms, software, models, and tools to advance #plantscience.
Let me know in the comments or DM if you'd like to be added.
go.bsky.app/KcVXefi
Let me know in the comments or DM if you'd like to be added.
go.bsky.app/KcVXefi