Josh Osowicki
@joshosowicki.bsky.social
Melbourne 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘱𝘺𝘰𝘨𝘦𝘯𝘦𝘴 researchers have been dealing with a similar challenge too…
www.theguardian.com/australia-ne...
www.theguardian.com/australia-ne...
Buruli ulcer: flesh-eating bacteria spreads in Melbourne suburb amid warning about rise in cases
Increase in cases ‘linked to Ascot Vale’ leads health officials to warn the disease is ‘spreading geographically’
www.theguardian.com
September 20, 2025 at 10:26 AM
Melbourne 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘱𝘺𝘰𝘨𝘦𝘯𝘦𝘴 researchers have been dealing with a similar challenge too…
www.theguardian.com/australia-ne...
www.theguardian.com/australia-ne...
Some NICUs don’t specifically cover anaerobes for NEC, although more to do with understanding of the developing GI microbiome. Your Q isn’t whether anaerobes are there, more what happens if we don’t go out of our way to treat them? There are some cholangitis & asp pneumonia studies 🤷♂️
August 22, 2025 at 7:55 PM
Some NICUs don’t specifically cover anaerobes for NEC, although more to do with understanding of the developing GI microbiome. Your Q isn’t whether anaerobes are there, more what happens if we don’t go out of our way to treat them? There are some cholangitis & asp pneumonia studies 🤷♂️
🤔 could consider when clindamycin was abandoned for IAI (because rising Bacteroides-R). If this was preceded by ⬆️ refractory cases that would be convincing-ish. And how about before any of these drugs were available? Anaerobic culture standards probably haven’t been consistent enough to be useful.
August 22, 2025 at 7:55 PM
🤔 could consider when clindamycin was abandoned for IAI (because rising Bacteroides-R). If this was preceded by ⬆️ refractory cases that would be convincing-ish. And how about before any of these drugs were available? Anaerobic culture standards probably haven’t been consistent enough to be useful.
August 13, 2025 at 5:41 PM
Reposted by Josh Osowicki
Thanks for the reference! And of course there's this classic from @tonybreu.bsky.social x.com/tony_breu/st...
Tony Breu on X: "1/ Why hasn't syphilis developed resistance to penicillin (PCN)? It took staph aureus about a year to demonstrate resistance. After 75 years, there has never been a reported case of treponema pallidum resistant to PCN. Let’s have a look at why this might be..." / X
1/ Why hasn't syphilis developed resistance to penicillin (PCN)? It took staph aureus about a year to demonstrate resistance. After 75 years, there has never been a reported case of treponema pallidum resistant to PCN. Let’s have a look at why this might be...
x.com
July 18, 2025 at 11:50 AM
Thanks for the reference! And of course there's this classic from @tonybreu.bsky.social x.com/tony_breu/st...
Many, perhaps most, of the deaths from ‘nephropathies’ (8%) and heart disease (12%) would have been infection-related so >2/3 deaths likely infection-related. Many, probably most, due to APSGN & RHD (i.e. #StrepA). Guess what? 🇺🇸 made a vaccine (it worked). 🌏 needs to do it again.
July 13, 2025 at 6:22 PM
Many, perhaps most, of the deaths from ‘nephropathies’ (8%) and heart disease (12%) would have been infection-related so >2/3 deaths likely infection-related. Many, probably most, due to APSGN & RHD (i.e. #StrepA). Guess what? 🇺🇸 made a vaccine (it worked). 🌏 needs to do it again.
It becomes the Thesis of Theseus.
June 24, 2025 at 10:32 AM
It becomes the Thesis of Theseus.