Joseph Sun Lab
@josephsunlab.bsky.social
Professor at Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College. My lab is interested in immune responses against cancer and infection.
https://www.mskcc.org/research/ski/labs/joseph-sun
https://www.mskcc.org/research/ski/labs/joseph-sun
Greetings from Stockholm. We celebrated the 50th year anniversary of NK cells, and the legacy of Eva and George Klein… in the Klein lecture hall at the Karolinska Institute! Historical tributes and entertaining stories from Hans Wigzell, Rolf Kiessling, Klas Karre, Wayne Yokoyama, and Lewis Lanier!!
October 16, 2025 at 9:41 PM
Greetings from Stockholm. We celebrated the 50th year anniversary of NK cells, and the legacy of Eva and George Klein… in the Klein lecture hall at the Karolinska Institute! Historical tributes and entertaining stories from Hans Wigzell, Rolf Kiessling, Klas Karre, Wayne Yokoyama, and Lewis Lanier!!
Reposted by Joseph Sun Lab
Working with rare immune populations? We describe an optimized low-input ATAC-seq workflow for tissue ILCs, allowing for reproducible epigenetic profiling. Technical report now out at EJI @EurJImmunol: onlinelibrary.wiley.com/doi/10.1002/.... Have a look!
Low‐Input Assay for Transposase‐Accessible Chromatin Identifies Epigenetic Signatures of Liver Group 1 Innate Lymphoid Cells
Assessing chromatin accessibility in rare cell populations within tissue remains a key challenge. To address this, we present a low-input ATAC workflow optimized for liver ILCs. The protocol is valid...
onlinelibrary.wiley.com
October 6, 2025 at 7:06 AM
Working with rare immune populations? We describe an optimized low-input ATAC-seq workflow for tissue ILCs, allowing for reproducible epigenetic profiling. Technical report now out at EJI @EurJImmunol: onlinelibrary.wiley.com/doi/10.1002/.... Have a look!
Have a look at this new study by Dr. Celeste Dang in @natimmunol.nature.com showing an interesting new role for the transcription factor TCF19 in driving antiviral NK cell function. Congrats Celeste for driving this one to the finish line! @mskcancercenter.bsky.social
TCF19 drives a broad transcriptional program that potentiates optimal innate and adaptive functions of antiviral NK cells - Nature Immunology
Sun and colleagues report that the transcription factor TCF19 regulates calcium signaling and cell cycling progression in NK cells and is required for innate and adaptive NK cell responses to viral in...
www.nature.com
August 8, 2025 at 1:17 PM
Have a look at this new study by Dr. Celeste Dang in @natimmunol.nature.com showing an interesting new role for the transcription factor TCF19 in driving antiviral NK cell function. Congrats Celeste for driving this one to the finish line! @mskcancercenter.bsky.social
These curious-looking flyers appeared in our hallways this week! They announce Celeste Dang’s thesis defense on Monday. Good luck Celeste!!
July 19, 2025 at 3:02 AM
These curious-looking flyers appeared in our hallways this week! They announce Celeste Dang’s thesis defense on Monday. Good luck Celeste!!
Wonderful to catch up with two former @wcm-imp.bsky.social grad students at this @faseborg.bsky.social meeting! So proud of alum who are now faculty running their own labs- Priya Issuree (U Iowa) and Ruth Franklin @ruthfranklinlab.bsky.social (Harvard). Nothing makes a program director more happy!
June 30, 2025 at 2:27 PM
Wonderful to catch up with two former @wcm-imp.bsky.social grad students at this @faseborg.bsky.social meeting! So proud of alum who are now faculty running their own labs- Priya Issuree (U Iowa) and Ruth Franklin @ruthfranklinlab.bsky.social (Harvard). Nothing makes a program director more happy!
Check out this new study and TCR Tg mouse generated by Endi Santosa @endicytosis.bsky.social. If you are interested in studying classic and inflationary CD8+ T cell memory to MCMV infection, we’re happy to share this mouse, and @laboxenius.bsky.social is extremely generous with her Tg lines as well.
Defining molecular circuits of CD8+ T cell responses in tissues during latent viral infection | Journal of Experimental Medicine | Rockefeller University Press
Our findings reveal a divergent transcriptomic and epigenetic landscape between conventional and inflationary memory responses in spleen and liver during l
rupress.org
May 20, 2025 at 1:51 PM
Check out this new study and TCR Tg mouse generated by Endi Santosa @endicytosis.bsky.social. If you are interested in studying classic and inflationary CD8+ T cell memory to MCMV infection, we’re happy to share this mouse, and @laboxenius.bsky.social is extremely generous with her Tg lines as well.
Reposted by Joseph Sun Lab
(1/2) In a study published in @cp-immunity.bsky.social, MSK's @josephsunlab.bsky.social and Dr. Rebecca Delconte found that fasting can supercharge the immune system's “natural killer” cells, a type of white blood cells that can kill #cancer cells.
April 18, 2025 at 5:33 PM
(1/2) In a study published in @cp-immunity.bsky.social, MSK's @josephsunlab.bsky.social and Dr. Rebecca Delconte found that fasting can supercharge the immune system's “natural killer” cells, a type of white blood cells that can kill #cancer cells.
Congratulations to Dr. Endi Santosa @endicytosis.bsky.social on his latest study on cooperativity of IRF4 and IRF8 in antiviral NK cells!
On a side note, this is the 10th paper I’ve published in @jimmunol.bsky.social throughout my career - very proud to support @aai.org and our society journal!
On a side note, this is the 10th paper I’ve published in @jimmunol.bsky.social throughout my career - very proud to support @aai.org and our society journal!
Cutting Edge: Cooperative interferon regulatory factor network shapes the NK-cell antiviral response
Abstract. Natural killer (NK) cells are innate lymphocytes that exhibit adaptive traits particularly evident during cytomegalovirus (CMV) infection. Follow
academic.oup.com
April 5, 2025 at 1:40 PM
Congratulations to Dr. Endi Santosa @endicytosis.bsky.social on his latest study on cooperativity of IRF4 and IRF8 in antiviral NK cells!
On a side note, this is the 10th paper I’ve published in @jimmunol.bsky.social throughout my career - very proud to support @aai.org and our society journal!
On a side note, this is the 10th paper I’ve published in @jimmunol.bsky.social throughout my career - very proud to support @aai.org and our society journal!
Thrilled that Dr. Adriana Mujal has been awarded the Kravis WiSE postdoctoral fellowship! There is no one more deserving! @mskcancercenter.bsky.social
Read about Adriana’s scientific journey here:
www.mskcc.org/news/meet-4-...
Read about Adriana’s scientific journey here:
www.mskcc.org/news/meet-4-...
Meet the Winners of the 2025 Kravis WiSE Fellowships
MSK is proud to announce that four Sloan Kettering Institute (SKI) researchers have been named 2025 Marie-Josée Kravis Women in Science Endeavor (Kravis WiSE) fellowship grant recipients.
www.mskcc.org
March 25, 2025 at 2:28 PM
Thrilled that Dr. Adriana Mujal has been awarded the Kravis WiSE postdoctoral fellowship! There is no one more deserving! @mskcancercenter.bsky.social
Read about Adriana’s scientific journey here:
www.mskcc.org/news/meet-4-...
Read about Adriana’s scientific journey here:
www.mskcc.org/news/meet-4-...
Reposted by Joseph Sun Lab
So happy to see this story come together. Check it out! Kathleen Mills and many collaborators - GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus | Science Immunology www.science.org/doi/10.1126/...
GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus
During mold infection, epithelial-derived GM-CSF licenses neutrophil killing of fungal cells, leading to improved survival.
www.science.org
March 21, 2025 at 7:57 PM
So happy to see this story come together. Check it out! Kathleen Mills and many collaborators - GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus | Science Immunology www.science.org/doi/10.1126/...
Fun visit to UCLA today, where my former postdoc (Professor Tim O’Sullivan) gave me a nice welcome, and I had a wonderful dinner and discussions with scientific “grandkids” 😊 In the current and difficult environment we are all going through, it was an important reminder of why we love what we do!!
March 14, 2025 at 6:05 AM
Fun visit to UCLA today, where my former postdoc (Professor Tim O’Sullivan) gave me a nice welcome, and I had a wonderful dinner and discussions with scientific “grandkids” 😊 In the current and difficult environment we are all going through, it was an important reminder of why we love what we do!!
Celebrate the amazing women in your labs!! #InternationalWomensDay
March 9, 2025 at 4:38 AM
Celebrate the amazing women in your labs!! #InternationalWomensDay
Incredibly proud of our NYC scientific community for standing up for SCIENCE! @standupforscience.bsky.social
March 7, 2025 at 9:15 PM
Incredibly proud of our NYC scientific community for standing up for SCIENCE! @standupforscience.bsky.social
Reposted by Joseph Sun Lab
MSK has been recognized as one of the national's top workplaces for inclusion and diversity by @newsweek.com magazine. 🎉
MSK earned five stars, the highest ranking, among mid to large employers in America. Learn more: www.newsweek.com/rankings/ame...
MSK earned five stars, the highest ranking, among mid to large employers in America. Learn more: www.newsweek.com/rankings/ame...
America's Greatest Workplaces for Inclusion & Diversity 2025
Newsweek is partnering with Plant-A Insights Group to honor America's Greatest Workplaces for Inclusion & Diversity 2025. These companies are committed to fostering an inclusive and diverse work envir...
www.newsweek.com
March 4, 2025 at 6:36 PM
MSK has been recognized as one of the national's top workplaces for inclusion and diversity by @newsweek.com magazine. 🎉
MSK earned five stars, the highest ranking, among mid to large employers in America. Learn more: www.newsweek.com/rankings/ame...
MSK earned five stars, the highest ranking, among mid to large employers in America. Learn more: www.newsweek.com/rankings/ame...
Congratulations to Dr. Adriana Mujal on this @cp-immunity.bsky.social study demonstrating a new role for an age old cytokine! www.cell.com/immunity/ful...
Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells
NK cells possess innate and adaptive features, but unlike T and B cells, NK cells
are not thought to require priming in lymphoid organs. Mujal et al. demonstrate that
the spleen supports enhanced expa...
www.cell.com
February 28, 2025 at 6:25 PM
Congratulations to Dr. Adriana Mujal on this @cp-immunity.bsky.social study demonstrating a new role for an age old cytokine! www.cell.com/immunity/ful...
Reposted by Joseph Sun Lab
Can dietary restriction enhance the efficacy of cancer #immunotherapy? MSK cancer immunologist Dr. Rebecca Delconte shares insights from a recent study (via The Scientist). #medsky
Timing Nutrition to Boost Antitumor Immunity
Intermittent fasting in mice enhances natural killer cells’ cancer-fighting abilities.
www.the-scientist.com
February 20, 2025 at 7:32 PM
Can dietary restriction enhance the efficacy of cancer #immunotherapy? MSK cancer immunologist Dr. Rebecca Delconte shares insights from a recent study (via The Scientist). #medsky
Reposted by Joseph Sun Lab
We're hiring at all levels! Feel free to reach out if you have questions:
academicjobsonline.org/ajo/jobs/29722
academicjobsonline.org/ajo/jobs/29722
Cornell University, Microbiology & Immunology
Full service online faculty recruitment and application management system for academic institutions worldwide. We offer unique solutions tailored for academic communities.
academicjobsonline.org
February 14, 2025 at 5:30 PM
We're hiring at all levels! Feel free to reach out if you have questions:
academicjobsonline.org/ajo/jobs/29722
academicjobsonline.org/ajo/jobs/29722
Reposted by Joseph Sun Lab
“Americans who value the spirit of discovery — and eagerly await new ways to confront disease, strengthen our economy and improve the quality of human life — need to issue a strong outcry… This is not a fight that our country can afford to lose.” Indeed
www.nytimes.com/2025/02/14/o...
www.nytimes.com/2025/02/14/o...
Opinion | American Science is Under Attack
The Trump administration hobbles research and endangers the public health.
www.nytimes.com
February 15, 2025 at 12:55 PM
“Americans who value the spirit of discovery — and eagerly await new ways to confront disease, strengthen our economy and improve the quality of human life — need to issue a strong outcry… This is not a fight that our country can afford to lose.” Indeed
www.nytimes.com/2025/02/14/o...
www.nytimes.com/2025/02/14/o...
Reposted by Joseph Sun Lab
Happy International day of women and girls in science! Thanks @josephsunlab.bsky.social for celebrating us today and every day!!
February 11, 2025 at 6:07 PM
Happy International day of women and girls in science! Thanks @josephsunlab.bsky.social for celebrating us today and every day!!
Reposted by Joseph Sun Lab
🚀 New to Bluesky? Dive into the Immunology & Microbial Pathogenesis (IMP) community! 🌟 Follow our starter pack of IMP faculty accounts to stay connected, learn, and engage with the latest in research & updates: go.bsky.app/97vN2qB
December 12, 2024 at 9:07 PM
🚀 New to Bluesky? Dive into the Immunology & Microbial Pathogenesis (IMP) community! 🌟 Follow our starter pack of IMP faculty accounts to stay connected, learn, and engage with the latest in research & updates: go.bsky.app/97vN2qB
Reposted by Joseph Sun Lab
Merry Christmas from the @josephsunlab.bsky.social 🎄🎅🏼 Another year of fun with the BEST colleagues. White elephant, cookie exchange and hot pot!! What a treat and with huge thanks to #MSKFunFund 🙏🏽
December 19, 2024 at 1:51 PM
Merry Christmas from the @josephsunlab.bsky.social 🎄🎅🏼 Another year of fun with the BEST colleagues. White elephant, cookie exchange and hot pot!! What a treat and with huge thanks to #MSKFunFund 🙏🏽
Reposted by Joseph Sun Lab
In 2024, Researchers at MSK continued to make discoveries to advance the global understand of #cancer and develop new therapies.
Here's a look back at some of the most exciting scientific discoveries reported over the past year, in chronological order ⬇️
Here's a look back at some of the most exciting scientific discoveries reported over the past year, in chronological order ⬇️
Top Cancer Research Advances at MSK in 2024
MSK researchers continued to make strides against cancer in 2024. Learn about some of their top discoveries.
www.mskcc.org
December 19, 2024 at 9:47 PM
In 2024, Researchers at MSK continued to make discoveries to advance the global understand of #cancer and develop new therapies.
Here's a look back at some of the most exciting scientific discoveries reported over the past year, in chronological order ⬇️
Here's a look back at some of the most exciting scientific discoveries reported over the past year, in chronological order ⬇️
We have moved our graduate school account to Bluesky… check us out! @wcm-imp.bsky.social
November 23, 2024 at 3:15 PM
We have moved our graduate school account to Bluesky… check us out! @wcm-imp.bsky.social
hello to everyone on bluesky!
November 18, 2024 at 9:21 AM
hello to everyone on bluesky!