Another preprint: We explored how the antibody framework (i.e. parts of variable region away from Ab-Ag interface) can be exploited to fine-tune antibody effector functions. www.biorxiv.org/content/10.1...

#ImmunoSky Happy to share our new work led by recently graduated Dongjun Guo - exploring how #antibody heavy and light chains form specific pairs. Fine-tuning an antibody language model, we asked how pairing propensities change in #bcell maturation and in diseases. 📄 www.biorxiv.org/content/10.1...