John Maciejowski
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johnmaciejowski.bsky.social
John Maciejowski
@johnmaciejowski.bsky.social
Associate Member at MSKCC
New preprint from the lab led by Yanyang Chen identifies BAF as a key regulator of TREX1 activity at micronuclei.
ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei https://www.biorxiv.org/content/10.1101/2025.04.14.648782v1
April 16, 2025 at 11:39 AM
Reposted by John Maciejowski
@johnmaciejowski.bsky.social we are looking forward to your presentation at #IOSCD25 in Malta🌞 Please share with your followers to let them know early bird registration & talk submission close on 01 May!
Find out more: bit.ly/IOSCD25_Talk...
March 18, 2025 at 12:43 PM
Reposted by John Maciejowski
Our new #IOSCD25 series highlights inter-organelle crosstalk through the lens of stress responses - bringing together experts in genome stability, organelle biology, inflammation & disease to spark collaboration & new discoveries🔬✨
Submit an abstract ➡️ bit.ly/IOSCD25_Subm...
February 20, 2025 at 9:46 AM
Please check out our preprint where we find that mitotic transcription helps ensure ecDNA inheritance through chromosomal tethering:

www.biorxiv.org/content/10.1...
www.biorxiv.org
February 17, 2025 at 11:04 AM