Joe Zaki
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joezaki.bsky.social
Joe Zaki
@joezaki.bsky.social
mysterious af. Postdoc studying sleep and memory. PhD in Neuroscience from Denise Cai’s lab at Mount Sinai
Reposted by Joe Zaki
Interested in how neural communication breaks down in a model of Alzheimer's pathology?

In a new preprint, we found desynchronization in medial entorhinal–hippocampal circuits that coincided with the onset of spatial memory deficits in 3xTg mice. (1/6)

www.biorxiv.org/content/10.1...
January 22, 2025 at 4:34 PM
Reposted by Joe Zaki
📣 As promised, here is our protocol paper on chemotagging! This new technique combines calcium imaging with chemogenetics to identify cell types in commonly used Miniscope recordings & can be used to tag ANY CELL TYPE! #Neuroskyence

Read about the technique here: www.biorxiv.org/content/10.1...
January 15, 2025 at 6:35 PM
Reposted by Joe Zaki
A special thanks to NIH Director Dr. Monica Bertagnolli for featuring the Icahn School of Medicine's @denisejcai.bsky.social's & lead author @joezaki.bsky.social's latest research in the NIH Director's Blog👉 tinyurl.com/bdf8y2vt

SEE THE PAPER HERE👉 www.nature.com/articles/s41...
December 5, 2024 at 10:43 PM
Reposted by Joe Zaki
Thank you to NIH Director Dr. Bertagnolli for sharing our recent work in her latest blog post! I’m so proud of the team and first author @joezaki.bsky.social for all their hard work on these exciting new findings examining stress & memory-linking 🧠

Read here 👇
directorsblog.nih.gov/2024/12/05/s...
Study Suggests New Experiences Can Refresh Memories of Past Events, with Implications for Understanding PTSD
Your memories of life experiences are encoded in collections of neurons in the brain that were active at the time the event took place. Later, those same patterns of neural activity are replayed in…
directorsblog.nih.gov
December 5, 2024 at 9:54 PM
Reposted by Joe Zaki
❓ Do you know what the anterior hypothalamic nucleus (AHN) does? No? Neither did we! 🧠

In a new preprint from the Cai Lab, learn how we discovered the AHN’s central role in regulating stress vulnerability.

Read the paper here: www.biorxiv.org/content/10.1... (1/6)
November 22, 2024 at 7:32 PM
Reposted by Joe Zaki
Honored to be featured alongside @sjo09.bsky.social in a recent article from The Transmitter! We love studying #memory stability & flexibility and how #stress can modify these processes! 🧠

Thank you for writing a lovely piece highlighting my lab’s work, @claudia-lopez.bsky.social!
November 20, 2024 at 3:19 PM
Reposted by Joe Zaki
🌟 Cai Lab Nature (@natureportfolio.bsky.social) paper alert! In work led by Joe Zaki, we find that rest periods after learning not only stabilize new memories BUT ALSO integrate new memories with older ones from days past! (1/10)

Read it here: www.nature.com/articles/s41...
November 19, 2024 at 4:50 PM