Joern Pezoldt
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joern-pezoldt.bsky.social
Joern Pezoldt
@joern-pezoldt.bsky.social
PostDoc@EPFL 🇨🇭 | Product development with phenomic single cell profiling
Getting integrated imaging and sequencing per cell off the ground with IRIS took a lot of grind. Countless iterations across every component. 📸+🧬=😍
I want to highlight three key craftspeople who built, established, and coded what made IRIS work (preprint at thread end).
December 22, 2025 at 11:42 AM
Building IRIS meant turning a 'simple' idea into an integrated deterministic microfluidic instrument that combines imaging<>transcriptomes per cell. Those five years were full of “0→1” moments; each essential for making IRIS reality.
December 10, 2025 at 1:45 PM
Now IRIS brings imaging<>transcriptome data together on a per-cell basis | #phenomic data at scale bridging the gap between molecular signatures and functional phenotype.

We spent five years building a technology rooted in who we are: Techies.
www.biorxiv.org/content/10.1...
Single-cell phenomics through integrated imaging and molecular profiling
Single-cell technologies such as transcriptomics, microscopy, and flow cytometry have revolutionized the study of cellular identity and function. While each of these technologies is powerful on its ow...
www.biorxiv.org
December 4, 2025 at 12:48 PM