Joanne Bright
@joannebright.bsky.social
ME Sufferer. Mild from Glandular Fever 1986, Severe from Flu 2000. Chronic Lyme too. Currently Borrelia free. 6 DecodeME genes mutated, 5of6 SNP'S too. Biggest threat is Persistent Infections. Alternative medicine detects my infections, the NHS does not!
If she's been a nurse for nearly 40 years, let's hope she hasn't got that long before she retires! 🤞 Good riddance to her ignorance & cruelty. Most sick people enter hospital for appropriate testing & treatment to alleviate their suffering. No such luck for #pwME
August 18, 2025 at 8:25 PM
If she's been a nurse for nearly 40 years, let's hope she hasn't got that long before she retires! 🤞 Good riddance to her ignorance & cruelty. Most sick people enter hospital for appropriate testing & treatment to alleviate their suffering. No such luck for #pwME
Found a paper on NAD+. With Curcumin, I am currently ⬆️dosages of Nicotinamide Riboside instead (it's NAD+ precusor VitB3- better 4 immune function?) Niacin (histamine🚩) deficiency can cause cognitive impairment. Not yet sure if plain Nicotinamide is ok for MCAS pmc.ncbi.nlm.nih.gov/articles/PMC...
NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway
Microglial-mediated neuroinflammation plays an important role in vascular dementia, and modulating neuroinflammation has emerged as a promising treatment target. Nicotinamide adenine dinucleotide (NAD...
pmc.ncbi.nlm.nih.gov
August 11, 2025 at 11:37 AM
Found a paper on NAD+. With Curcumin, I am currently ⬆️dosages of Nicotinamide Riboside instead (it's NAD+ precusor VitB3- better 4 immune function?) Niacin (histamine🚩) deficiency can cause cognitive impairment. Not yet sure if plain Nicotinamide is ok for MCAS pmc.ncbi.nlm.nih.gov/articles/PMC...
Thought of 1 more thing. @itsmepz.bsky.social makes a good point about LDN (which I don't think I would tolerate), as I get terrible cognition if I catch Epstein Barr & it's left undiagnosed & untreated. Get rid of infections.
August 11, 2025 at 9:11 AM
Thought of 1 more thing. @itsmepz.bsky.social makes a good point about LDN (which I don't think I would tolerate), as I get terrible cognition if I catch Epstein Barr & it's left undiagnosed & untreated. Get rid of infections.
Hope you get lots of answers as a difficult question. Depends on cause of brain fog. Phosphatidylcholine supplement supports acetylcholine production for cognitive function, Curcumin/Turmeric will bring down brain inflamation if that's the cause of fog. could need Vit B12, low Estrogen levels. etc.
August 11, 2025 at 8:23 AM
Hope you get lots of answers as a difficult question. Depends on cause of brain fog. Phosphatidylcholine supplement supports acetylcholine production for cognitive function, Curcumin/Turmeric will bring down brain inflamation if that's the cause of fog. could need Vit B12, low Estrogen levels. etc.
Thanks so much. Found it invaluable information without the RS no's. Let's hope it will do some good with those hospitals who are currently abusing patients.
August 8, 2025 at 3:22 PM
Thanks so much. Found it invaluable information without the RS no's. Let's hope it will do some good with those hospitals who are currently abusing patients.
Have you seen anywhere Naomi please people quoting RS marker numbers for the 8/9 genes, because all the genes appear on 23andme raw data, but lots of lines for each gene name? I'm guessing it's only one marker, not all e.g. 57 of the same gene name? Didn't see id. marker nos on DecodeME website. x
August 8, 2025 at 10:53 AM
Have you seen anywhere Naomi please people quoting RS marker numbers for the 8/9 genes, because all the genes appear on 23andme raw data, but lots of lines for each gene name? I'm guessing it's only one marker, not all e.g. 57 of the same gene name? Didn't see id. marker nos on DecodeME website. x
Grateful for you posting this Naomi as I'm not in a position to spend too much time on socials or research to fully understand what's going on. David Putrino's post yesterday was great too.
August 8, 2025 at 7:37 AM
Grateful for you posting this Naomi as I'm not in a position to spend too much time on socials or research to fully understand what's going on. David Putrino's post yesterday was great too.