JKNowak Lab
@jknowaklab.bsky.social
Institute of Biochemistry and Biophysics PAS, Warsaw, POLAND
We study the mechanisms that are responsible for the synthesis of developmentally regulated non-coding RNAs and their role in programmed genome rearrangements.
We study the mechanisms that are responsible for the synthesis of developmentally regulated non-coding RNAs and their role in programmed genome rearrangements.
Reposted by JKNowak Lab
🧬mRNA vaccines played a key role in controlling the spread of the pandemic. However, mRNA itself is an exceptionally unstable molecule. This limits its effectiveness - for example, by shortening the duration of action. In our research, we examined these limitations
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Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines - Nature
Upon intramuscular administration, COVID-19 mRNA vaccines are primarily taken up by macrophages, in which the cellular machinery extends their poly(A) tails, thereby increasing mRNA stability and tran...
www.nature.com
April 16, 2025 at 6:00 PM
🧬mRNA vaccines played a key role in controlling the spread of the pandemic. However, mRNA itself is an exceptionally unstable molecule. This limits its effectiveness - for example, by shortening the duration of action. In our research, we examined these limitations
👨🔬👩🔬
👨🔬👩🔬