Prof Joseph F Hayes
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jfhayes.bsky.social
Prof Joseph F Hayes
@jfhayes.bsky.social
Searching for better mental health treatments
Prof of Psychiatry, Division of Psychiatry, UCL
Honorary General Adult Psychiatrist, NLFT
Group Leader, aiMH-lab
Co-founder & CMO, juli Inc
This is not to say no one experiences symptoms on discontinuation of antidepressants, but trial data don’t show us this and they are the best method we have to find a causal association between antidepressants cessation and symptoms.
July 9, 2025 at 7:28 PM
Why would researchers want to inflate the problem? It’s probably both ideological and financial www.wired.com/story/taperi...
‘Uber for Getting Off Antidepressants’ Launches in the US
Outro, which is now available in seven states, wants to help people taper off antidepressants without experiencing debilitating side effects.
www.wired.com
July 9, 2025 at 7:25 PM
Certainly from trials we see there is a unique profile of discontinuation symptoms, but the clinical impact is far less than some researchers would have you believe.
July 9, 2025 at 7:23 PM
What about the lack of spell checker for comments? Shows me how much of my typing is just mashing the keyboard.
March 5, 2025 at 5:17 PM
This target trial emulation study of >25k patients finds no difference in total cholesterol at one year, but lower BMI and BP. And no difference in psychiatric hospital admission rates journals.plos.org/plosmedicine...
Comparative cardiometabolic safety and effectiveness of aripiprazole in people with severe mental illness: A target trial emulation
In a target trial emulation, Alvin Richards-Belle and colleagues compare the efficacy and safety profile of aripiprazole and other second-generation antipsychotics in patients diagnosed with severe me...
journals.plos.org
January 27, 2025 at 1:42 PM
Great work from @Alvin Richards-Belle et al.
December 18, 2024 at 10:09 PM
High dose prescribing is more likely for: people with schizophrenia, minoritized ethic groups, younger people, men and people from more deprived areas
December 18, 2024 at 10:09 PM
If bipolar then it’s quetiapine:
December 18, 2024 at 10:09 PM
The patterns differ by diagnosis. If you have a schizophrenia, you are most likely to get olanzapine:
December 18, 2024 at 10:09 PM
Hi there! Yes please
November 16, 2024 at 1:18 PM