Jean-Ehrland RICCI
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jer-06.bsky.social
Jean-Ehrland RICCI
@jer-06.bsky.social
450 followers 580 following 38 posts
INSERM research director & metabolism-lover, studying metabolism in cancer & immunity, Nice, France.
Editor-in-Chief of Oncogenesis www.nature.com/oncsis
#cancermetabolism #immunometabolism #mitophagy #CAR-T - www.c3m-nice.fr/en/Teams/team-03/
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Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check how this study demonstrates that targeting KAT2A with a PROTAC degrader decreases MYCN activity and inhibits NB cell proliferation, which hold the potential to make a significant impact on the management of this aggressive childhood cancer.
November 13, 2025 at 8:40 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
“MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma”

🔵 Groundbreaking research led by Carol J. Thielehas been featured in #Oncogenesis.

▶️ Read the full open access article here: www.nature.com/articles/s41...
November 13, 2025 at 8:39 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check how their findings reveal that targeting NFATc1 simultaneously restricts biosynthetic precursors and impairs cell cycle progression in CRC, suggesting that NFATc1 inhibition is a promising therapeutic strategy.
November 11, 2025 at 10:41 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
“NFATc1-mediated activation of the pentose phosphate pathway and cell cycle dysregulation collectively drive tumor progression”

🔵 Can Huang’s latest research is now available to read in #Oncogenesis.

▶️ Read the full open access article here: www.nature.com/articles/s41...
November 11, 2025 at 10:41 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check how this study unveils the involvement of the EPHA5-STAT3 signaling pathway in Follicular Thyroid Cancer and how this discovery offers a promising new target for genetic intervention in the its treatment.
November 7, 2025 at 9:53 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
“EPHA5 promotes cell proliferation and inhibits apoptosis in Follicular Thyroid Cancer via the STAT3 signaling pathway”

🔵 Interesting research led by Yongfu Zhao has been featured in #Oncogenesis.

▶️ Read the full open access article here: www.nature.com/articles/s41...
November 7, 2025 at 9:53 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check how this study highlights LINC01432 as a potential therapeutic target for overcoming resistance in high-risk multiple myeloma.
November 4, 2025 at 8:02 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
"Investigation of lncRNA expression in newly diagnosed multiple myeloma reveals a LINC01432-CELF2 axis as an inhibitor of apoptosis"

🔵 Jessica Silva-Fisher latest and outstanding research is now available to read in #Oncogenesis.

▶️ Read the open access article here: www.nature.com/articles/s41...
November 4, 2025 at 8:02 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check how this study demonstrates that SYT7 functions as an oncoprotein in NPC, driving tumor progression through its regulation of ALDH1A3-mediated glycolysis and STAT3 signaling pathways, revealing its potential as a biomarker for the prediction and treatment of NPC.
October 30, 2025 at 8:19 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
“SYT7 accelerates nasopharyngeal carcinoma progression via ALDH1A3-mediated STAT3 signaling activation”

🔵 Interesting research led by Xinxin Xiang has been featured in #Oncogenesis.

▶️ Read the full open access article here: www.nature.com/articles/s41...
October 30, 2025 at 8:19 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Special thanks to the Scientific Committee:
Laurent Le Cam, @fredericbost.bsky.social, Alice Carrier, Nathalie Mazure, @jer-06.bsky.social, Stéphane Rocchi, Rodrigue Rossignol, Jean-Emmanuel Sarry & Sophie Vasseur.
October 27, 2025 at 2:35 PM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
📢 Coming soon: Oncogenesis will publish a meeting report and launch a Special Issue on Metabolism and Cancer, featuring insights from 13 leading experts. Stay tuned! 👀
October 27, 2025 at 2:29 PM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
🔬 Oncogenesis at the 6th Metabolism & Cancer Meeting 🔬

We were proud to support the 6th Metabolism & Cancer Meeting, held on 8–10 October in La Grande-Motte, France.

#CancerResearch #Metabolism #Oncogenesis #ScientificMeeting
October 27, 2025 at 2:27 PM
Reposted by Jean-Ehrland RICCI
fondationarc.bsky.social
Romain RISCAL (IRCM - Institut de Recherche en Cancérologie de Montpellier) et Eric Solary (Gustave Roussy, Vice‑président de la Fondation ARC pour la recherche sur le cancer).
October 22, 2025 at 9:18 AM
Reposted by Jean-Ehrland RICCI
fondationarc.bsky.social
Jacqueline Lehmann-Che (Institut de Recherche Saint-Louis (IRSL/UMR 1342), Paris), Camille Lobry (Institut de Recherche Saint-Louis (IRSL/UMR 1342), Thomas Mercher ( @gustaveroussy.fr
Research, Villejuif), Julie Pannequin (Institut de Génomique Fonctionnelle - IGF, Montpellier)
October 22, 2025 at 9:18 AM
Reposted by Jean-Ehrland RICCI
fondationarc.bsky.social
Ce matin, nous avons ouvert les 𝟐𝟗ᵉ 𝐉𝐨𝐮𝐫𝐧𝐞́𝐞𝐬 𝐉𝐞𝐮𝐧𝐞𝐬 𝐂𝐡𝐞𝐫𝐜𝐡𝐞𝐮𝐫𝐬 𝐞𝐧 𝐜𝐚𝐧𝐜𝐞́𝐫𝐨𝐥𝐨𝐠𝐢𝐞 sous le signe du partage scientifique.💡 Nous sommes fiers de soutenir cette nouvelle génération de chercheurs passionnés et audacieux.✨
#FondationARC #JournéesJeunesChercheurs #RechercheContreLeCancer #ScienceEtPartage
October 22, 2025 at 9:02 AM
Reposted by Jean-Ehrland RICCI
aliciakowaltowski.bsky.social
Our newest publication is out, and it is most certainly a colorful one!!

Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners.

febs.onlinelibrary.wiley.com/doi/10.1002/...
October 20, 2025 at 9:39 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check the working model the author propose where HOTAIR serves as a scaffold enhancing the interaction between MEST and super-enhancers, increasing MEST expression, promoting glioblastoma cell proliferation and invasive migration, and ultimately contributing to tumor progression.
October 16, 2025 at 9:19 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
“A HOTAIR-associated super-enhancer orchestrates glioblastoma malignancy via MEST”

🔵 Interesting research led by Jiandang Shi has been featured in #Oncogenesis.

▶️ Read the full open access article here: www.nature.com/articles/s41...
October 16, 2025 at 9:18 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
Check how this study underscored the significant role of glycoRNAs in glioma proliferation and provided a foundation for further research into their potential as novel biomarkers and therapeutic targets for glioma.
October 14, 2025 at 7:11 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
“GlycoRNAs are abundant in glioma and involved in glioma cell proliferation”

🔵 Lin Wang latest research is now available to read in #Oncogenesis.

▶️ Read the full open access article here: www.nature.com/articles/s41...
October 14, 2025 at 7:11 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
In my role as AE for Oncogenesis, I look for translation potential and solid experimental work in a manuscript. I believe such studies are key to advancing science as well as cancer care.

–Maarten

Delighted to have him on our team at #Oncogenesis! 🤝
October 9, 2025 at 8:58 AM
Reposted by Jean-Ehrland RICCI
oncogenesisnature.bsky.social
But also aim to ascertain efficacy from novel interventions or stratification modalities in early phase clinical studies.
October 9, 2025 at 8:57 AM