@jenswalter15.bsky.social
With big thanks to @isappscience.bsky.social for organizing the podcast and to @colinhillucc.bsky.social and Daniel Trancredi for being great hosts and for asking very interesting questions.
April 24, 2025 at 10:32 AM
With big thanks to @isappscience.bsky.social for organizing the podcast and to @colinhillucc.bsky.social and Daniel Trancredi for being great hosts and for asking very interesting questions.
Thank you to Dalimil Bujdos and Paul O'Toole from @ucc.ie, @uccmicrobiology.bsky.social, and @apcmicrobiomeirel.bsky.social for a fun collaboration that continues to teach me a lot.
March 25, 2025 at 4:31 PM
Thank you to Dalimil Bujdos and Paul O'Toole from @ucc.ie, @uccmicrobiology.bsky.social, and @apcmicrobiomeirel.bsky.social for a fun collaboration that continues to teach me a lot.
aurora was validated on model species. For example, differences in host predictions and proportion of autochthonous strains differ vastly between strictly host-adapted Limosilactobacillus reuteri and nomadic Lactiplantibacillus plantarum.
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
aurora: a machine learning gwas tool for analyzing microbial habitat adaptation - Genome Biology
A primary goal of microbial genome-wide association studies is identifying genomic variants associated with a particular habitat. Existing tools fail to identify known causal variants if the analyzed ...
genomebiology.biomedcentral.com
March 25, 2025 at 4:31 PM
aurora was validated on model species. For example, differences in host predictions and proportion of autochthonous strains differ vastly between strictly host-adapted Limosilactobacillus reuteri and nomadic Lactiplantibacillus plantarum.
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Register here for free tickets to the book launch with the Creators, March 10th, Lapps Quay, Cork, Ireland. bit.ly/3EVxa15
Find us on Instagram and Facebook under
@nimediet.
Find us on Instagram and Facebook under
@nimediet.
Microsoft Forms
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March 3, 2025 at 9:52 AM
Register here for free tickets to the book launch with the Creators, March 10th, Lapps Quay, Cork, Ireland. bit.ly/3EVxa15
Find us on Instagram and Facebook under
@nimediet.
Find us on Instagram and Facebook under
@nimediet.
I am indebted to the two co-leads, Dale Archer and Maria Elisa Perez-Munoz, the students and staff that helped with the experiments, and the many esteemed collaborators that contributed to this work.
February 28, 2025 at 2:44 PM
I am indebted to the two co-leads, Dale Archer and Maria Elisa Perez-Munoz, the students and staff that helped with the experiments, and the many esteemed collaborators that contributed to this work.
We think this work is important as it shows that even a bacterial species considered beneficial can have negative long-term effects on autoimmunity, and it establishes a molecular foundation for strain-specific differences. Relevant for the development of microbial therapeutics.
February 28, 2025 at 2:44 PM
We think this work is important as it shows that even a bacterial species considered beneficial can have negative long-term effects on autoimmunity, and it establishes a molecular foundation for strain-specific differences. Relevant for the development of microbial therapeutics.
We found considerable strain-level differences in the effects of L. reuteri to cause spontaneous RR-EAE. R2lc, a strain that activates AhR through the pks gene cluster, resulted in severe EAE, while a pks mutant of R2lc and a pks-negative strain (PB-W1) failed to exacerbate EAE.
February 28, 2025 at 2:44 PM
We found considerable strain-level differences in the effects of L. reuteri to cause spontaneous RR-EAE. R2lc, a strain that activates AhR through the pks gene cluster, resulted in severe EAE, while a pks mutant of R2lc and a pks-negative strain (PB-W1) failed to exacerbate EAE.
Big thanks also to the Weston Family Microbiome Initiative, PrecisionBiotics (now Novonesis), and @researchireland.bsky.social for funding, and @ualberta.bsky.social, @ucc.bsky.social, @apcmicrobiomeirel.bsky.social and all institutions involved for their support.
January 23, 2025 at 5:10 PM
Big thanks also to the Weston Family Microbiome Initiative, PrecisionBiotics (now Novonesis), and @researchireland.bsky.social for funding, and @ualberta.bsky.social, @ucc.bsky.social, @apcmicrobiomeirel.bsky.social and all institutions involved for their support.
Deeply indebted to the many brilliant collaborators and team members that contributed to this research. This was a team effort! Thanks to Fuyong Li and Anissa Armet for great teamwork as co-first authors, and Carla Prado for supervision of the project in Alberta after I left.
January 23, 2025 at 5:10 PM
Deeply indebted to the many brilliant collaborators and team members that contributed to this research. This was a team effort! Thanks to Fuyong Li and Anissa Armet for great teamwork as co-first authors, and Carla Prado for supervision of the project in Alberta after I left.
Given the rather exciting clinical effects, we decided to give this diet a name: Non-industrialized Microbiome Restore (NiMe™) Diet.
Recipes used in this trial, and additional information, are or will be freely available here: instagram.com/nimediet/
Recipes used in this trial, and additional information, are or will be freely available here: instagram.com/nimediet/
January 23, 2025 at 5:10 PM
Given the rather exciting clinical effects, we decided to give this diet a name: Non-industrialized Microbiome Restore (NiMe™) Diet.
Recipes used in this trial, and additional information, are or will be freely available here: instagram.com/nimediet/
Recipes used in this trial, and additional information, are or will be freely available here: instagram.com/nimediet/