Jeff Hsiao
@jeffreychsiao.bsky.social
Postdoc in the Peter Tsvetkov Lab at Beth Israel Deaconess Medical Center / Broad Institute
Reposted by Jeff Hsiao
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis https://www.biorxiv.org/content/10.1101/2025.09.09.674576v1
September 12, 2025 at 8:30 PM
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis https://www.biorxiv.org/content/10.1101/2025.09.09.674576v1
Reposted by Jeff Hsiao
New preprint out!
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis
A quick twitorial 🧵
www.biorxiv.org/content/10.1...
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis
A quick twitorial 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org
September 13, 2025 at 2:07 PM
New preprint out!
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis
A quick twitorial 🧵
www.biorxiv.org/content/10.1...
Deep Mutational Scanning of FDX1 Identifies Key Structural Determinants of Lipoylation and Cuproptosis
A quick twitorial 🧵
www.biorxiv.org/content/10.1...
Reposted by Jeff Hsiao
Check out our lab's latest paper describing a mutually inhibitory complex between DPP9 and KEAP1
www.jbc.org/article/S002...
www.jbc.org/article/S002...
The Serine Protease DPP9 and the Redox Sensor KEAP1 Form a Mutually Inhibitory Complex
Synthetic inhibitors of the serine protease DPP9 activate the related NLRP1 and CARD8
inflammasomes and stimulate powerful innate immune responses. Thus, it seems plausible
that a biomolecule similarl...
www.jbc.org
November 29, 2024 at 5:14 PM
Check out our lab's latest paper describing a mutually inhibitory complex between DPP9 and KEAP1
www.jbc.org/article/S002...
www.jbc.org/article/S002...