Jason Keagy
@jasonkeagy.bsky.social
Animal behavior, cognition, and genomics; dad; biker (of the pedal variety); likes finding and watching critters; keagylab.com
There’s a corresponding Penn State News article here: www.psu.edu/news/researc... (6/6)
Threatened by warming waters, brook trout may be able to adapt to hotter weather | Penn State University
Brook trout may have a genetic trick up their scales when it comes to adapting, with limitations, to heatwaves that threaten their existence. A novel study led by researchers at Penn State suggests th...
www.psu.edu
April 9, 2025 at 9:26 PM
There’s a corresponding Penn State News article here: www.psu.edu/news/researc... (6/6)
Also from a personal side of things, this was a massive undertaking that, quite frankly, I still can’t believe we pulled off. Kudos to grad student Sarah Batchelor for leading the field and lab work and @marathon-rana.bsky.social for some creative analysis of a truly insane dataset. (5/n)
April 9, 2025 at 9:26 PM
Also from a personal side of things, this was a massive undertaking that, quite frankly, I still can’t believe we pulled off. Kudos to grad student Sarah Batchelor for leading the field and lab work and @marathon-rana.bsky.social for some creative analysis of a truly insane dataset. (5/n)
* Overall change in expression patterns was more intense during the second heatwave. We think the first heatwave "primed" response for the second heatwave.
* This is an example of the landscape transcriptomics approach we've been advocating: onlinelibrary.wiley.com/doi/10.1111/... (4/n)
* This is an example of the landscape transcriptomics approach we've been advocating: onlinelibrary.wiley.com/doi/10.1111/... (4/n)
Landscape transcriptomics as a tool for addressing global change effects across diverse species
Landscape transcriptomics is an emerging field studying how genome-wide expression patterns reflect dynamic landscape-scale environmental drivers, including habitat, weather, climate, and contaminant....
onlinelibrary.wiley.com
April 9, 2025 at 9:26 PM
* Overall change in expression patterns was more intense during the second heatwave. We think the first heatwave "primed" response for the second heatwave.
* This is an example of the landscape transcriptomics approach we've been advocating: onlinelibrary.wiley.com/doi/10.1111/... (4/n)
* This is an example of the landscape transcriptomics approach we've been advocating: onlinelibrary.wiley.com/doi/10.1111/... (4/n)
* Many of the genes we identified as responding to heatwaves have been identified in lab work as potential biomarkers. We show these likely have utility in wild pops where things are "messier". (3/n)
April 9, 2025 at 9:26 PM
* Many of the genes we identified as responding to heatwaves have been identified in lab work as potential biomarkers. We show these likely have utility in wild pops where things are "messier". (3/n)
Some key points:
* Across the four pops of brook trout sampled we saw consistent and strong transcriptomic response to the heat waves.
* There was also some variability bw pops in gene expression response and some of this variability can be attributed to genetic differences between the pops. (2/n)
* Across the four pops of brook trout sampled we saw consistent and strong transcriptomic response to the heat waves.
* There was also some variability bw pops in gene expression response and some of this variability can be attributed to genetic differences between the pops. (2/n)
April 9, 2025 at 9:26 PM
Some key points:
* Across the four pops of brook trout sampled we saw consistent and strong transcriptomic response to the heat waves.
* There was also some variability bw pops in gene expression response and some of this variability can be attributed to genetic differences between the pops. (2/n)
* Across the four pops of brook trout sampled we saw consistent and strong transcriptomic response to the heat waves.
* There was also some variability bw pops in gene expression response and some of this variability can be attributed to genetic differences between the pops. (2/n)
Every time I moved and transitioned to a new job, this paper got put on the backburner, and then it took awhile to find a journal that saw its potential (thanks Proc B!), but NEVER GIVE UP! (6/6)
August 22, 2024 at 7:48 PM
Every time I moved and transitioned to a new job, this paper got put on the backburner, and then it took awhile to find a journal that saw its potential (thanks Proc B!), but NEVER GIVE UP! (6/6)
This was my first foray into transcriptomics which has become an important tool for my current lab. It also was the first large grant I ever wrote AND received (thanks BEACON Center!) (5/6)
August 22, 2024 at 7:47 PM
This was my first foray into transcriptomics which has become an important tool for my current lab. It also was the first large grant I ever wrote AND received (thanks BEACON Center!) (5/6)
There’s a lot in this paper, but the most interesting result was that gene expression in the brains of female stickleback fish changed dynamically depending on the male traits the female was exposed to, and this response differed between sympatric closely-related species. (4/6)
August 22, 2024 at 7:46 PM
There’s a lot in this paper, but the most interesting result was that gene expression in the brains of female stickleback fish changed dynamically depending on the male traits the female was exposed to, and this response differed between sympatric closely-related species. (4/6)
We used the benthic-limnetic species-pair stickleback system to characterize gene expression in the brains of females making mate choice decisions. (3/6)
August 22, 2024 at 7:43 PM
We used the benthic-limnetic species-pair stickleback system to characterize gene expression in the brains of females making mate choice decisions. (3/6)
Mate choice plays a key role in the generation and maintenance of new species, but little is known about the molecular mechanisms influencing these important decisions. (2/6)
August 22, 2024 at 7:42 PM
Mate choice plays a key role in the generation and maintenance of new species, but little is known about the molecular mechanisms influencing these important decisions. (2/6)