Lars Jansen Lab
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jansenlab.bsky.social
Lars Jansen Lab
@jansenlab.bsky.social
Discovering Mechanisms of Chromatin Inheritance at the University of Oxford www.jansenlab.org
The discovery of CENP-A, the centromere-specific histone H3 variant turns 40 years!
Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out.
link.springer.com/article/10.1...
July 29, 2025 at 11:05 AM
Fresh of the press! rdcu.be/egmY0 We discovered key chromatin modifications that are heritably maintained through mitotic cell divisions in the absence of continued transcription. These hold a memory of past exposure to interferon-gamma, priming cells for future activation of gene expression.
April 4, 2025 at 10:22 AM
@bencarty.bsky.social and the team did a fantastic job in a wonderful collaboration with @naltemose.bsky.social as well as Dani Fachinetti and Simona Giunta’s teams to help define the molecular basis for maintaining centromeric chromatin size and position. www.biorxiv.org/content/10.1...
February 5, 2025 at 5:33 PM
Join our team www.jansenlab.org as a @wellcometrust.bsky.social -funded postdoctoral fellow and help us discover how chromatin at human centromeres is formed and inherited. Position now open at @oxfordbiochemistry.bsky.social! See: my.corehr.com/pls/uoxrecru... for details!
December 17, 2024 at 9:19 PM