James Gallagher
@jamesgallagher.bsky.social
Dynamic catalysis and nonequilibrium chemistry.
Postdoc Toste Group at UC Berkeley, PhD Leigh Group at UoM.
Postdoc Toste Group at UC Berkeley, PhD Leigh Group at UoM.
Pinned
Structure-performance relationships for catalysis-driven molecular machinery
Molecular machine properties such as speed, efficiency, power, and torque depend upon
particular features of structure, mechanism, and chemistry. The graphical abstract
shows a Top Trumps-style repres...
www.cell.com
In biology, molecular machines exist to perform useful functions. Artificial molecular machines now move in the same way as those in biology, but they do not yet perform tasks. Out now in Chem, a guide to task performance in molecular machinery. www.cell.com/chem/fulltex...
@cp-chem.bsky.social
@cp-chem.bsky.social
Reposted by James Gallagher
Online now: Structure-performance relationships for catalysis-driven molecular machinery
Structure-performance relationships for catalysis-driven molecular machinery
Molecular machine properties such as speed, efficiency, power, and torque depend upon particular features of structure, mechanism, and chemistry. The graphical abstract shows a Top Trumps-style representation of key performance indicators, illustrating how the first generation of synthetic catalysis-driven small-molecule machines compare with their biomolecular analogs. The understanding of how molecular machine design affects properties should aid technological advancements and a deeper understanding of the fundamental principles that link physics, chemistry, and biology.
dlvr.it
October 3, 2025 at 3:34 PM
Online now: Structure-performance relationships for catalysis-driven molecular machinery
The physics of molecular machinery can be confusing. We developed a plug-and-play interactive tool based on trajectory thermodynamics. The user can now visualise how/why motors move directionally or respond to a force (see video), without knowledge of the physics or maths.
github.com/JoaquinBaixe...
github.com/JoaquinBaixe...
October 3, 2025 at 6:13 PM
The physics of molecular machinery can be confusing. We developed a plug-and-play interactive tool based on trajectory thermodynamics. The user can now visualise how/why motors move directionally or respond to a force (see video), without knowledge of the physics or maths.
github.com/JoaquinBaixe...
github.com/JoaquinBaixe...
In biology, molecular machines exist to perform useful functions. Artificial molecular machines now move in the same way as those in biology, but they do not yet perform tasks. Out now in Chem, a guide to task performance in molecular machinery. www.cell.com/chem/fulltex...
@cp-chem.bsky.social
@cp-chem.bsky.social
Structure-performance relationships for catalysis-driven molecular machinery
Molecular machine properties such as speed, efficiency, power, and torque depend upon
particular features of structure, mechanism, and chemistry. The graphical abstract
shows a Top Trumps-style repres...
www.cell.com
October 3, 2025 at 2:47 PM
In biology, molecular machines exist to perform useful functions. Artificial molecular machines now move in the same way as those in biology, but they do not yet perform tasks. Out now in Chem, a guide to task performance in molecular machinery. www.cell.com/chem/fulltex...
@cp-chem.bsky.social
@cp-chem.bsky.social
Reposted by James Gallagher
Information ratchets drive many molecular motors, but we can also use them for other nonequilibrium processes like performing error correction in a molecular recognition process to increase selectivity. Published today in @natnano.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An information ratchet improves selectivity in molecular recognition under non-equilibrium conditions - Nature Nanotechnology
An abiotic information ratchet mechanism increases selectivity for the correct DNA duplex from 2:1 at equilibrium to 6:1 under energy-dissipating conditions.
www.nature.com
August 1, 2025 at 9:51 AM
Information ratchets drive many molecular motors, but we can also use them for other nonequilibrium processes like performing error correction in a molecular recognition process to increase selectivity. Published today in @natnano.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by James Gallagher
I’m excited to share that I will be moving to the University of Ulm as a junior group leader and I have a fully-funded open PhD position co-supervised by me and Max von Delius @mvdelius.bsky.social . Apply at benjamin.roberts@unipd.it, any shares would be appreciated!
www.bmwrlab.com/work-with-us
www.bmwrlab.com/work-with-us
Work with us | The Roberts Lab
www.bmwrlab.com
February 24, 2025 at 4:02 PM
I’m excited to share that I will be moving to the University of Ulm as a junior group leader and I have a fully-funded open PhD position co-supervised by me and Max von Delius @mvdelius.bsky.social . Apply at benjamin.roberts@unipd.it, any shares would be appreciated!
www.bmwrlab.com/work-with-us
www.bmwrlab.com/work-with-us
Reposted by James Gallagher
Peng-Lai, @stefanborsley.bsky.social, Martin & our collaborators Alessandro and @giusepponelab.bsky.social demonstrate how a catalyst transduces chemical energy to perform mechanical work in www.nature.com/articles/s41... in @nature.com. tinyurl.com/jny7nen5. Animation @scicommstudios.bsky.social😀
January 15, 2025 at 4:08 PM
Peng-Lai, @stefanborsley.bsky.social, Martin & our collaborators Alessandro and @giusepponelab.bsky.social demonstrate how a catalyst transduces chemical energy to perform mechanical work in www.nature.com/articles/s41... in @nature.com. tinyurl.com/jny7nen5. Animation @scicommstudios.bsky.social😀