James Isbister
banner
james-isbister.bsky.social
James Isbister
@james-isbister.bsky.social
Scientist @Open Brain Institute @openbraininst🇨🇭
Postdoc @EPFL_en Blue Brain Project
DPhil @universityofoxford
Precise neural coding principles (time-warped spike time patterns)
Large biophysically-detailed brain models
Check out our work to fully extract spines from EM at booth 3631 at #sfn2025 and learn how to analyse them on our brand new platform for brain simulation openbraininstitute.org/sfn-2025
#sfn2025 | James Isbister
Travelling to #SfN2025 with a VR headset showing the incredible work of Marwan Abdellah and Michael Reimann who have developed algorithms to repair neuronal electron microscopy meshes and extract almo...
www.linkedin.com
November 13, 2025 at 9:02 PM
Excited for what’s coming over the next 6 months
Neuroscience is entering the digital age!

Today, we proudly launch the Open Brain Institute (OBI)—a revolutionary non-profit organization dedicated to advancing neuroscience from the physical realm into the virtual world.
March 19, 2025 at 10:40 AM
Reposted by James Isbister
Neuroscience is entering the digital age!

Today, we proudly launch the Open Brain Institute (OBI)—a revolutionary non-profit organization dedicated to advancing neuroscience from the physical realm into the virtual world.
March 18, 2025 at 1:27 PM
To conclude the Blue Brain Project last year, composer Hana Ajiashvili presented music she wrote when she came across our visualizations online. It felt like she was making tangible hypotheses about the brain, and reminded me of how we think when we enter the field: www.youtube.com/watch?v=2h3I...
Eye in the Sky by Hana Ajiashvili and Blue Brain Project
YouTube video by Hana Ajiashvili
www.youtube.com
March 6, 2025 at 9:58 AM
A beautiful video of the Blue Brain Project's improved CCFv3 annotation and Nissl atlas of the entire mouse brain building upon the @alleninstitute.bsky.social atlas. Recommend watching end-to-end. Great work by Sébastien Piluso @cyrillefavreau.bsky.social and others

www.youtube.com/watch?v=upul...
An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain
YouTube video by Blue Brain Project - EPFL
www.youtube.com
December 9, 2024 at 8:11 PM
An old news article describing our finding of time-warped cortical spike time patterns. Looking forward to sharing our exciting new results on this soon

actu.epfl.ch/news/neurons...
Neurons warp space and time
The messages sent between neurons look something like a Morse code, but the closer one looks the more mysterious the code becomes. The code is called the neural code and is the holy grail in neuroscie...
actu.epfl.ch
December 9, 2024 at 7:57 PM
Just a pretty video of our rat non-barrel somatosensory cortex model: actu.epfl.ch/news/empower...

www.youtube.com/watch?v=7g0q...
A morphologically-detailed model of rat somatosensory regions
YouTube video by Blue Brain Project - EPFL
www.youtube.com
December 9, 2024 at 7:48 PM
Reposted by James Isbister
Spike sorting biases and information loss in a detailed cortical model https://www.biorxiv.org/content/10.1101/2024.12.04.626805v1
December 8, 2024 at 1:15 AM