Jake Leyhr
jakeleyhr.bsky.social
Jake Leyhr
@jakeleyhr.bsky.social
Postdoc in Sherwood Lab @ Duke University. Worms and cell invasion.
Previously vertebrate skeletal/craniofacial Evo-Devo PhD @ Uppsala University.
#Embryo23
Here's some rendered anterior and ventral views of the crazy jaw and toothplates in a young juvenile 🤩 (Lower jaw in red, upper jaw in sky blue)
January 18, 2025 at 11:23 PM
To my knowledge, this is the first detailed 3D imaging of the triple ligament that tethers together the OSS, tripus, and the anterior face of the swim bladder. 12/
January 17, 2025 at 4:02 PM
We described the juvenile-adult development of ICL1 along with the other Weberian ligaments, showing they are all mature by 10mm SL. 11/
January 17, 2025 at 4:02 PM
Histologically, ICL1 closely resembles the interossicular ligament (IOL), with densely packed, taut collagen-1 fibers (unlike the elastin-rich suspensor ligament; SUS), suggesting it strains to hold rib 4/oss in place. 10/
January 17, 2025 at 4:02 PM
We found that ICL1 bridges features of Weberian and posterior intercostal ligaments, with a unique medial attachment at a steep angle aligned with the os suspensorium (OSS), unlike the slack, flattened posterior ICLs (green). 9/
January 17, 2025 at 4:02 PM
While I was segmenting the area slice by slice, working in axial/sagittal/coronal views, I noticed a small hint of soft tissue running backwards from the fourth rib, and when I segmented it, I saw that it connected rib 4 to rib 5. 6/
January 17, 2025 at 4:02 PM
The Weberian apparatus (WA) refers primarily to the four heavily modified cervical vertebrae of Otophysan fish (10,000 species) that form a chain of small bones and interconnecting ligaments to connect the swim bladder to the inner ear. 2/
January 17, 2025 at 4:02 PM