@jakecolautti.bsky.social
Excited to share our recent work on the structure of a membrane-depolarizing toxin secreted by the human pathogen Pseudomonas aeruginosa! Hugely grateful to @alexanderbelyy.bsky.social and @dshatskiy.bsky.social for their work on this project, and to John Whitney for his support and guidance.
Cryo-EM structure of a type VI secretion system delivered membrane-depolarizing toxin involved in bacterial antagonism https://www.biorxiv.org/content/10.1101/2025.04.30.651342v1
May 2, 2025 at 12:24 AM
Excited to share our recent work on the structure of a membrane-depolarizing toxin secreted by the human pathogen Pseudomonas aeruginosa! Hugely grateful to @alexanderbelyy.bsky.social and @dshatskiy.bsky.social for their work on this project, and to John Whitney for his support and guidance.
Thrilled to share our recent work on a family of antibacterial proteins that can kill a wide range of Gram-positive bacteria by a number of different mechanisms of action. Extremely grateful to @stephenrgarrett.bsky.social and John Whitney for their guidance.
Proteolytically activated antibacterial toxins inhibit the growth of diverse Gram-positive bacteria https://www.biorxiv.org/content/10.1101/2025.04.13.648598v1
April 14, 2025 at 8:11 PM
Thrilled to share our recent work on a family of antibacterial proteins that can kill a wide range of Gram-positive bacteria by a number of different mechanisms of action. Extremely grateful to @stephenrgarrett.bsky.social and John Whitney for their guidance.