Dr Jaime Pitts
@jaimedoesxlms.bsky.social
Research fellow, Scarff group in LICAMM. Crosslinking-MS and integrative structural biology for inherited heart disease. Ex-kinase nerd. (She/Her)
Reposted by Dr Jaime Pitts
3.5 yr funded PhD studentship available in my lab October start. Exploring cardiac myosin modulators with cryoEM and mass spec. Get in touch if interested. Apply before 28th July. www.findaphd.com/phds/project...
Unravelling the mechanisms of action of cardiac myosin modulators in health and heart disease at University of Leeds on FindAPhD.com
PhD Project - Unravelling the mechanisms of action of cardiac myosin modulators in health and heart disease at University of Leeds, listed on FindAPhD.com
www.findaphd.com
June 16, 2025 at 6:54 PM
3.5 yr funded PhD studentship available in my lab October start. Exploring cardiac myosin modulators with cryoEM and mass spec. Get in touch if interested. Apply before 28th July. www.findaphd.com/phds/project...
Reposted by Dr Jaime Pitts
Swinging lever mechanism of myosin shown by time-resolved cryoEM www.nature.com/articles/s41... so glad to finally be able to share this with the community! @astburycentre.bsky.social @astbury-bsl.bsky.social @stemuench.bsky.social @snmcmillan.bsky.social @davidklebl.bsky.social
Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM - Nature
A study using time-resolved cryogenic electron microscopy reveals the swinging lever mechanism of myosin, providing information on the molecular basis behind the production of force and movement by my...
www.nature.com
April 9, 2025 at 5:19 PM
Swinging lever mechanism of myosin shown by time-resolved cryoEM www.nature.com/articles/s41... so glad to finally be able to share this with the community! @astburycentre.bsky.social @astbury-bsl.bsky.social @stemuench.bsky.social @snmcmillan.bsky.social @davidklebl.bsky.social
Really proud of the qXL-MS work developed to build this story with the beautiful Cryo-EM structures from @snmcmillan.bsky.social
Mechanism of mavacamten inhibition of myosin - check out our preprint here: www.biorxiv.org/content/10.1...
Mavacamten inhibits myosin activity by stabilising the myosin interacting-heads motif and stalling motor force generation
Most sudden cardiac deaths in young people arise from hypertrophic cardiomyopathy, a genetic disease of the heart muscle, with many causative mutations found in the molecular motor beta-cardiac myosin...
www.biorxiv.org
February 18, 2025 at 11:31 AM
Really proud of the qXL-MS work developed to build this story with the beautiful Cryo-EM structures from @snmcmillan.bsky.social
Starting the year off right with a very pretty spectrum from an experiment showing no interaction between two proteins that should be interacting.
January 2, 2025 at 9:00 AM
Starting the year off right with a very pretty spectrum from an experiment showing no interaction between two proteins that should be interacting.
My gaming laptop was bought six years ago to mostly play CS:GO now its fragging of a different kind. 9 hours to searching....
June 10, 2024 at 9:51 AM
My gaming laptop was bought six years ago to mostly play CS:GO now its fragging of a different kind. 9 hours to searching....
Thank you to the angels who updated MSFragger and Skyline so analysis of MeroX data is somewhat practical just in time for my birthday!
I’m just a women standing in front of buckets of qXL-MS needing to be analysed and not wanting to use xlinkx….
I’m just a women standing in front of buckets of qXL-MS needing to be analysed and not wanting to use xlinkx….
April 12, 2024 at 5:31 PM
Thank you to the angels who updated MSFragger and Skyline so analysis of MeroX data is somewhat practical just in time for my birthday!
I’m just a women standing in front of buckets of qXL-MS needing to be analysed and not wanting to use xlinkx….
I’m just a women standing in front of buckets of qXL-MS needing to be analysed and not wanting to use xlinkx….
Last week the Scarff group hosted the Don of adenovirus myosin expression, this week I have to decipher my notes I took. Very excited to crack on with it!
November 20, 2023 at 9:43 AM
Last week the Scarff group hosted the Don of adenovirus myosin expression, this week I have to decipher my notes I took. Very excited to crack on with it!
UoLeeds are looking for a facility manager to join our team. If you want to be responsible for the day-to-day running of our mass spectrometry research service and facility equipment have a look at ad! Happy to answer queries!
jobs.leeds.ac.uk/vacancy.aspx...
jobs.leeds.ac.uk/vacancy.aspx...
Job Opportunity at University of Leeds: Mass Spectrometry Facility Manager
jobs.leeds.ac.uk
November 16, 2023 at 9:16 PM
UoLeeds are looking for a facility manager to join our team. If you want to be responsible for the day-to-day running of our mass spectrometry research service and facility equipment have a look at ad! Happy to answer queries!
jobs.leeds.ac.uk/vacancy.aspx...
jobs.leeds.ac.uk/vacancy.aspx...
Boy, would I love to chat to someone who’s got #skyline working for quantitative crosslinking ms! Please! Anyone! Because it looks like Wednesday is going to be watching YouTube videos about skyline with a lot of coffee.
November 7, 2023 at 7:54 PM
Boy, would I love to chat to someone who’s got #skyline working for quantitative crosslinking ms! Please! Anyone! Because it looks like Wednesday is going to be watching YouTube videos about skyline with a lot of coffee.
Rip the bird app; hello it’s replacement. I’m Jaime, I adore roller derby and Mass Spectrometry.
October 26, 2023 at 9:04 PM
Rip the bird app; hello it’s replacement. I’m Jaime, I adore roller derby and Mass Spectrometry.