Jack B. Roberts
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jackbroberts.bsky.social
Jack B. Roberts
@jackbroberts.bsky.social
Epigenetics | Gene Regulation | Osteoarthritis | Cartilage | Genetics

I’m a postdoc at Newcastle University working with Dr Sarah Rice 🧬🦴👨‍🔬
Pinned
A little late to sharing this, but we've recently published a report providing an overview of the research discussed at last year's OA epigenetics workshop in Toronto! A brilliant collaborative effort; read it here: www.sciencedirect.com/science/arti...
From mechanism to medicine: The progress and potential of epigenetics in osteoarthritis
Osteoarthritis (OA) is a chronic, degenerative disease of the articular joints. The disease presents an enormous clinical and economic burden globally…
www.sciencedirect.com
Reposted by Jack B. Roberts
Please share/repost widely: I have a postdoc position available. Please see ad below and reach out to apply.

academicpositions.harvard.edu/postings/15449
Postdoctoral Fellow in the Capellini Laboratory of Developmental and Evolutionary Genetics
The Department of Human Evolutionary Biology at Harvard University invites applications for a Postdoctoral Fellow in the Evolutionary and Developmental Genetics Laboratory of Dr. Terence D. Capellini....
academicpositions.harvard.edu
October 24, 2025 at 3:39 PM
Reposted by Jack B. Roberts
Truly an honor to be invited by #OARSI and @oacjournal.bsky.social to summarize all the amazing work in the genetics, genomics, and epigenetics of #osteoarthritis over the last year. A tough job with many great papers not included, but our review is now online: www.oarsijournal.com/article/S106...
September 20, 2025 at 2:40 AM
Reposted by Jack B. Roberts
Grateful @natrevchem.nature.com for the opportunity to share my #labdaptations with the scientific community!

Check out the article here: www.nature.com/articles/s41...

Also linked on my website, labdaptations.com
September 16, 2025 at 1:09 AM
Reposted by Jack B. Roberts
Super excited and thrilled to see this work come out in Nature today. 🥹@tdcapellini.bsky.social Thank you so much for your amazing mentorship throughout the project, and to all my co-authors who helped take this work to the next level.
August 27, 2025 at 4:08 PM
A little late to sharing this, but we've recently published a report providing an overview of the research discussed at last year's OA epigenetics workshop in Toronto! A brilliant collaborative effort; read it here: www.sciencedirect.com/science/arti...
From mechanism to medicine: The progress and potential of epigenetics in osteoarthritis
Osteoarthritis (OA) is a chronic, degenerative disease of the articular joints. The disease presents an enormous clinical and economic burden globally…
www.sciencedirect.com
May 16, 2025 at 10:13 AM
Reposted by Jack B. Roberts
Many congratulations to the newly elected chairs @thehopefulscie1.bsky.social , @jackbroberts.bsky.social for GRS Cartilage 2027.. Great to see the GRS is in safe hands..
March 24, 2025 at 7:28 PM
Reposted by Jack B. Roberts
We're advertising a fully-funded BBSRC PhD studentship @newcastleuni.bsky.social to work on understanding the biology of COLGALT2 in cartilage using/developing cool model systems w/ Dr James Henstock at @northumbriauni.bsky.social. Pls reach out if you are interested in applying! bit.ly/3DiqHN9
Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University on FindAPhD.com
PhD Project - Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University, listed on FindAPhD.com
bit.ly
March 3, 2025 at 2:06 PM
Reposted by Jack B. Roberts
1/11 Pleased to see our article by the terrific Dr. Daniel Richard
finally out in January 9th the journal Cell: www.cell.com/cell/fulltex...
Functional genomics of human skeletal development and the patterning of height heritability
A framework for understanding complex-trait genetic uncovers regulatory networks underpinning human height variability.
www.cell.com
January 10, 2025 at 11:47 AM
Reposted by Jack B. Roberts
We are advertising a fully funded PhD project starting September 2025. We’ve been excited for this for a long time- biologically unravelling the results of genetic studies to understand the mechanism of cartilage breakdown conferred by SNPs. Reach out if interested! www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University, listed on F...
www.findaphd.com
November 14, 2024 at 8:39 AM
Reposted by Jack B. Roberts
Here it is! The first paper from my lab is out today in #AJHG

In brief, we quantified the changing methylome through a large window of prenatal human articular cartilage development and identified methylation QTLs co-localising with 24 OA risk signals www.cell.com/ajhg/fulltex...
The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk
Emerging evidence supports developmental factors impacting osteoarthritis risk in older age. Here, we quantify the methylome of 72 human fetal knee cartilage samples and identify 24 independent osteoa...
www.cell.com
November 22, 2024 at 8:04 PM
Yesterday I successfully defended my PhD thesis! Massively grateful to my supervisory team Prof John Loughlin and @grainofscience.bsky.social for their mentorship, guidance and support over the last few years. And thank you to @mcdeandres.bsky.social for making the long journey over from A Coruña!!
November 22, 2024 at 6:57 PM
Reposted by Jack B. Roberts
Today we have the seminar of @mcdeandres.bsky.social who has very kindly stayed on to tell us all about the world of chondrocytes 😃
November 22, 2024 at 9:13 AM
Reposted by Jack B. Roberts
Congratulations Dr @jackbroberts.bsky.social! Very proud to witness the first in person viva of one of my students (I know you weren’t really mine but I’ve claimed you!). Thanks so much to @mcdeandres.bsky.social and Luke Gaughan for examining 🥂
November 22, 2024 at 9:01 AM