Ivan Mindlin
ivanmindlin.bsky.social
Ivan Mindlin
@ivanmindlin.bsky.social
Finishing PhD candidate at Paris Brain Institute. Enjoying the ride from computer science to complex systems and biology :)
🔗 fastDMF-powered implementation: github.com/Picardian14/...
pure Python version by Carlos :) github.com/carlosmig/Ho...

Thanks to all co-authors for the collaboration, and my colleague and friend @rherzoga.bsky.social for leading this work.

Feedback, reuse, and extensions are very welcome.
5/5
GitHub - Picardian14/fastHDMF-code
Contribute to Picardian14/fastHDMF-code development by creating an account on GitHub.
github.com
January 14, 2026 at 7:03 PM
Because inhibitory control is local and homeostatic, adaptiveness can be heterogeneous across regions while remaining stable. This enables coexisting SW and asynchronous regimes—chimeric-like—suggesting a potential mechanism to cognitive states such as local-sleep–related attentional lapses. 4/5
January 14, 2026 at 7:03 PM
In a high-coupling regime, the adaptive inhibitory feedback gives rise to bistable UP–DOWN dynamics (delta-range slow waves (SW) ), while faster adaptation supports asynchronous activity.
3/5
January 14, 2026 at 7:03 PM
In the DMF, resting-state activity emerges from noisy firing rates stabilized by feedback inhibitory control (FIC).
Previous implementations (e.g. fastDMF) use static inhibition. Here, we introduce a local plastic inhibitory rule that can dynamically self adjust toward homeostasis.

2/5
January 14, 2026 at 7:03 PM