IUSM SNRI Stem Cell Research Group
iustemcell.bsky.social
IUSM SNRI Stem Cell Research Group
@iustemcell.bsky.social
Updates and information about the Stem Cell Research Group at the Indiana University School of Medicine Stark Neurosciences Research Institute
New collaborative paper by #IUStemCell members Feng Guo and Scott Canfield, "Engineering blood–brain barrier microphysiological systems to model Alzheimer's disease monocyte penetration and infiltration"

pubs.rsc.org/en/content/a...
Engineering blood–brain barrier microphysiological systems to model Alzheimer's disease monocyte penetration and infiltration
Alzheimer's disease (AD) is a progressive and neurodegenerative disease, predominantly causing dementia. Despite increasing clinical evidence suggesting the involvement of peripheral immune cells such...
pubs.rsc.org
May 26, 2025 at 1:59 PM
Check out the latest research from the lab of #IUStemCell member Scott Canfield! In this study, they demonstrate that excessive alcohol levels impair the integrity of the blood-brain barrier in human stem cell-derived models, contributing to the onset or worsening of neurological disorders.
Alcohol diminishes barrier integrity in human stem cell-derived brain microvascular endothelial cells: Role of reactive oxygen species
The World Health Organization has linked alcohol consumption to over 200 diseases including neurodegenerative diseases. A dysfunctional blood–brain ba…
www.sciencedirect.com
May 19, 2025 at 12:16 PM
Congratulations to Feng Guo and his lab for their recent exciting publication in @cp-cellstemcell.bsky.social where they pursue the use of diffusible scaffolds for functional maturation of midbrain organoids! Very cool work!
Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids
Guo and colleagues developed vascular network-inspired diffusible (VID) scaffolds for engineering midbrain organoids, providing a versatile technology for organoid development and therapeutic innovati...
www.cell.com
May 4, 2025 at 12:49 AM
Happy to have hosted an informational session from @miltenyibiotec.bsky.social today! Great turnout to hear about some of the latest tools for stem cell research
April 10, 2025 at 12:16 AM
@iustemcell.bsky.social representing at the Wisconsin Stem Cell Symposium today! #IUStemCell
April 2, 2025 at 9:19 PM