Infectious Diseases Fellowship at Indiana University
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Infectious Diseases Fellowship at Indiana University
@iuidfellowship.bsky.social
#idboardreview #idfellows #idfellowship #IDsky #HIVsky #idmeded
#adenovirus treatment supportive care & decrease in immunosuppression. Antiviral tx is not supported by prospective RCT. However IV cidofovir is considered standard practice for severe, progressive, or disseminated adenovirus disease in most transplant centers. www.mdpi.com/2076-2607/11...
www.mdpi.com
November 14, 2025 at 12:43 AM
t.co/eyHRJoTWPY #adenovirus in immunocompromised @asm.org
https://cmr.asm.org/content/21/4/704
t.co
November 14, 2025 at 12:41 AM
#adenovirus dx
-positive serum adenovirus PCR with clinical and laboratory findings of hepatitis favors a probable diagnosis of adenoviral hepatitis.
-Definitive diagnosis requires a liver biopsy demonstrating viral inclusions.
November 14, 2025 at 12:41 AM
#adenovirus Immunocompromised host acquired by 1)reactivation of latent infection secondary to immunosuppression or 2)primary adenovirus infection; acquired from either ill contacts or from donor organ
November 14, 2025 at 12:40 AM
#adenovirus #hepatitis #Adenovirus affects epithelial cells in GI GU & respiratory tracts. In immunocompromised hosts: wide range of clinical presentations, including pneumonia, hepatitis, nephritis & hemorrhagic cystitis with a case fatality of 50%.
November 14, 2025 at 12:40 AM
sometimes we through ID mimics too
November 13, 2025 at 1:38 AM
ddx Also case reports of leishmania associated with tattoo in hiv or Iraqi war veteran; also small pox inoculation in tattoo by veterans post vaccine
November 12, 2025 at 11:31 PM
Red ink in tattoos can cause reactions, including non-infectious granulomatous reactions. Also in above article, there are reports of leprosy, TB, and syphilis being inoculated via tattoos as well!
November 12, 2025 at 11:30 PM
Treatment includes 2 agents for 4 months based on susceptibility (FQ, clarithro/azithro, doxy, linezolid, tmp/smx) for M fortuitum group
November 12, 2025 at 11:29 PM
M fortuitum and M abscessus has also been associated with LE folliculitis post pedicures
November 12, 2025 at 11:29 PM
Most of these infections are post traumatic injury: stepping on nail, motor vehicle accident, injuries to lower extremities
November 12, 2025 at 11:29 PM
#NTM M #fortuitum #SSTI pts generally don’t have any predisposing immunosuppression (as oppose to M chelonae/M abscessus)
November 12, 2025 at 11:29 PM
Rapidly growing mycobacteria #RGM M abscessus, M chelonae and M fortuitum are most common NTM causing SSTI in US. M fortuitum is responsible for 60% of localized infections in previously healthy pts
November 12, 2025 at 11:28 PM
#Mycobacterium fortuitum #NTM rare cause of tattoo associated infections: either ink mixed with tap water or outbreaks associated w/ contaminateded gray ink at the manufacturing plant
November 12, 2025 at 11:28 PM
treatment is discontinuation or dose reduction of sirolimus
November 11, 2025 at 10:50 PM