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ischemia1327.bsky.social
Ischemia
@ischemia1327.bsky.social
Inserm UMR 1327 ISCHEMIA
Membrane Signalling and Inflammation in reperfusion injuries
University of Tours, France
Director: Sébastien Roger
https://umr1327.univ-tours.fr/
Our PhD student, Johanna Augros, represented our lab exceptionally well at the International Society on Thrombosis and Haemostasis @isth.org meeting that took place in Washington. See you next year at the ISTH next meeting in Paris!
July 2, 2025 at 10:29 AM
Members of INSERM UMR1327 Ischemia: Mohammed ELMALLAH, Marylou PICHONNIERE and Oumnia BENOUNA were pleased to present their work yesterday, at the Annual meeting of the @frenchpurine.bsky.social in Paris. A meeting enriched by relevant scientific discussions.
July 1, 2025 at 1:41 PM
We thank the organizers of the PRESTO COST action meeting (Dublin, Ireland, 22-24/05), on the topic "Purinergic signalling: from bench-to-bedside, where are we now?"

Congratulations to our unit members W. ECHCHIH, M. PICHONNIERE, M. ElMALLAH, A. HERAUD-MELEY and O. BENOUNA for their presentations.
May 26, 2025 at 2:17 PM
Reposted by Ischemia
Synthèse sur "Les anticorps monoclonaux dans les maladies immuno-inflammatoires" dans le dernier N° de La Lettre du Pharmacologue, consacré à la pharmacologie de l'inflammation

par G. Paintaud, O. Le Tilly, D. Ternant, C. Desvignes et @theodorabejan.bsky.social

www.edimark.fr/revues/la-le...
Les anticorps monoclonaux dans les maladies immuno-inflammatoires | G. Paintaud, O. Le Tilly, D. Ternant, C. Desvignes, T. Bejan-Angoulvant
En 26 ans, 44 anticorps monoclonaux (AcMo), se fixant sur 28 antigènes cibles différents, ont obtenu une indication dans au moins une maladie immuno-inf
www.edimark.fr
May 14, 2025 at 8:01 AM
Yesterday, Oumnia Benouna, Ana Valéria Vinhais da Silva, Johanna Augros, Marylou Pichonnière, Claire Hosemans and Wiam Echchih (UMR1327), participated to a 10 km "Parcours du cœur" at Bergeonnerie Lake (Tours), a walk dedicated to raising awareness about heart health.

Thanks to the organizers!
May 12, 2025 at 2:01 PM
Reposted by Ischemia
Nous avons le plaisir de participer au programme "Ma thèse en BD" de l'université de Tours.

Les planches 2024-2025, réalisées par 3 dessinatrices/teurs avec 5 doctorant.es, sont téléchargeables et feront l'objet de plusieurs expos, notamment lors du festival 2025

saps.univ-tours.fr/decouvrez-le...
Découvrez les planches de la nouvelle édition "Ma thèse en BD" (2024-25)
Suite à un appel à participation lancé en septembre dernier, 5 doctorants et doctorantes ont été sélectionnés pour la 3e édition de 'Ma thèse en BD'. Le défi : illustrer ses travaux de recherche et so...
saps.univ-tours.fr
April 11, 2025 at 5:29 AM
Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy

Denis Angoulvant @dangoulvant.bsky.social is coauthor of this paper by Yishu Wang et al., published in NPJ Digit Med

rdcu.be/ehav0
Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy
npj Digital Medicine - Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy
rdcu.be
April 10, 2025 at 9:12 AM
Prognosis of patients with acute myocardial infarction in the setting of COVID-19: A French nationwide observational study

by Ahmad Abou Hamed, Maeva Gourraud, Thibaud Genet, François Barbier, Denis Angoulvant, Laurent Fauchier and Fabrice Ivanes

www.sciencedirect.com/science/arti...
Prognosis of patients with acute myocardial infarction in the setting of COVID-19: A French nationwide observational study
The prognosis of patients with acute myocardial infarction (AMI) in the setting of coronavirus disease 2019 (COVID-19) remains uncertain.To evaluate p…
www.sciencedirect.com
April 4, 2025 at 1:59 PM
Conférences Sport & Santé
le 21 mars à MAME (Tours) à 17h30

Un événement organisé par Tours Autogreffe
March 14, 2025 at 10:24 AM
Reposted by Ischemia
Nous sommes à la recherche de candidat.es pour notre poste d'Assistant Hospitalo-universitaire, qui sera disponible en novembre 2025.

Contacts : Theodora Bejan-Angoulvant @theodorabejan.bsky.social ou David Ternant

Merci de reposter !
March 12, 2025 at 1:03 PM
Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes:
protocol for a nationwide observational comparative study in routine care
bmjopen.bmj.com/content/15/1...
March 11, 2025 at 4:04 PM
Reposted by Ischemia
Publication of the PHARBEVACOL study protocol:
Bevacizumab-based chemotherapy adaptive to PK of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized phase III trial study
www.sciencedirect.com/science/arti...
Bevacizumab-based chemotherapy adaptive to pharmacokinetic of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized ph...
Bevacizumab shows inter-individual pharmacokinetic variability, with an exposure-response relationship in metastatic colorectal cancer (mCRC) patients…
www.sciencedirect.com
March 6, 2025 at 1:49 PM
Reposted by Ischemia
Bonjour, une action est signalée à Tours : standupforscience.fr/tous-les-eve... 👍
Tous les évènements | Stand Up For Science France
standupforscience.fr
March 4, 2025 at 12:40 PM
Outcomes in Atrial Fibrillation Patients with Different Clinical Phenotypes: Insights from the French Population

by A.M. Fawzy, A. Bisson, L. Lochon, T. Lenormand, G.Y.H. Lip and L. Fauchier

@liverpoolccs.bsky.social @chrudetours.bsky.social @chuorleans.bsky.social
www.mdpi.com/3171158
Outcomes in Atrial Fibrillation Patients with Different Clinical Phenotypes: Insights from the French Population
Background: Atrial fibrillation (AF) patients represent a clinically complex, heterogeneous population comprising multiple homogeneous cohorts. Purpose: We aimed to identify the common clinical phenot...
www.mdpi.com
March 4, 2025 at 3:35 PM
@dangoulvant.bsky.social is coauthor of

Quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial
www.sciencedirect.com/science/arti...
Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUAT...
Antithrombotic management in patients with chronic coronary syndrome and previous stent implantation who require long-term oral anticoagulation is hig…
www.sciencedirect.com
March 3, 2025 at 10:44 AM
TMA from peptide receptor radionuclide therapy

P Delalande, M Bobot, M Essig, C Simon, AP Jonville-Béra, C Barbet, B Sautenet, V Maisons, T Carsuzaa, F Bruyère and JM Halimi

@aphm-chu-marseille.bsky.social @hopambroisepare.bsky.social @chrudetours.bsky.social

www.sciencedirect.com/science/arti...
Thrombotic Microangiopathy From Peptide Receptor Radionuclide Therapy
www.sciencedirect.com
February 27, 2025 at 11:50 AM
Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes

in Eur J Prev Cardiol 2025

by A. Bisson and D. Angoulvant, Inserm UMR1327 and Departments of Cardiology of @chrudetours.bsky.social and @chuorleans.bsky.social

academic.oup.com/eurjpc/artic...
Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes
Arnaud Bisson, Denis Angoulvant; Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes, European Journal o
academic.oup.com
February 26, 2025 at 5:11 PM
Imaging flow cytometry for the diagnosis of HIT

by Carré J, Demont Y, Mouton C, Vayne C, Guéry EA, Voyer A, Garçon L, Le Guyader M, Demagny J
@chuamiens.bsky.social @chu-bordeaux.fr @chrudetours.bsky.social
in Br J Haematol 2025 @bsochaem.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...
Imaging flow cytometry as a novel approach for the diagnosis of heparin‐induced thrombocytopenia
Imaging flow cytometry (IFC) combines the advantages of flow cytometry (FC) and microscopy to provide detailed morphological insights into platelets. In this study, we evaluated the performance of mo...
onlinelibrary.wiley.com
February 20, 2025 at 8:34 AM
Reposted by Ischemia
Nous avons le plaisir de vous inviter aux 3ᵉ Journées Scientifiques du French Purine Club !
📅 30 juin à 14h au 1er juillet à 12h
📍 ESPCI, 10 rue Vauquelin, 75005 Paris
🔗 docs.google.com/forms/d/e/1F...

💡 Pensez aussi à votre cotisation annuelle
➡️ bit.ly/4hOcar6

Nous espérons vous y voir nombreux !
3e Journées Scientifiques du French Purine Club
ESPCI, 10 rue Vauquelin, 75005 Paris
docs.google.com
February 12, 2025 at 8:52 PM
A clinician viewpoint on the 2024 European guidelines on the management of patients with atrial fibrillation

by L Fauchier UMR1327 and @chrudetours.bsky.social, JC Deharo @aphm-chu-marseille.bsky.social, F Sacher @chu-bordeaux.fr and A Cohen @ap-hp.bsky.social
www.sciencedirect.com/science/arti...
A clinician viewpoint on the 2024 European guidelines on the management of patients with atrial fibrillation
www.sciencedirect.com
February 14, 2025 at 2:19 PM
Reposted by Ischemia
Evaluation of efficacy and safety of rituximab in patients with progressive interstitial lung disease with inflammatory component (EvER-ILD2): A multicentre double-blind placebo-controlled randomized trial

by M Ferreira, T Bejan-Angoulvant, S Marchand-Adam et al.
pubmed.ncbi.nlm.nih.gov/39693827/
Evaluation of efficacy and safety of rituximab in patients with progressive interstitial lung disease (ILD) with inflammatory component (EvER-ILD2): A multicentre double-blind placebo-controlled rando...
NCT05596786 (clinicaltrials.gov), EU-CT number 2022-500,375-31-00 (European Medicines agency).
pubmed.ncbi.nlm.nih.gov
February 3, 2025 at 9:23 AM
P2 purinergic receptors at the heart of pathological left ventricular remodeling following acute myocardial infarction

a review by AV Vinhais da Silva, S Chesseron, O Benouna, J Rollin, S Roger, T Bourguignon, S Chadet and F Ivanes

Am J Physiol Heart Circ Physiol
pubmed.ncbi.nlm.nih.gov/39884315/
P2 purinergic receptors at the heart of pathological left ventricular remodeling following acute myocardial infarction - PubMed
Pathological left ventricular remodeling is a complex process following an acute myocardial infarction, leading to architectural disorganization of the cardiac tissue. This phenomenon is characterized...
pubmed.ncbi.nlm.nih.gov
February 3, 2025 at 9:17 AM