Irma Jayawardana
irmusjay.bsky.social
Irma Jayawardana
@irmusjay.bsky.social
PhD student @grosselab
📍Freiburg, DE
From Napoli 🇮🇹
Reposted by Irma Jayawardana
Irma's @irmusjay.bsky.social paper is under the Christmas tree 'in press': Nuclear Myosin VI cooperates with actin to promote transcriptional cluster formation at androgen receptors doi: doi.org/10.1016/j.jb... including SIM imaging of myosin IV with actin on androgen receptors and RNA-Pol2
December 23, 2025 at 10:08 AM
Reposted by Irma Jayawardana
@manuelholst.bsky.social from our team had some fun and assembled this cool spatiotemporal juxtaposition of a actin-binding protein moving on a nuclear receptor - paper from our PhD student @irmusjay.bsky.social out soon!
December 22, 2025 at 4:03 PM
Reposted by Irma Jayawardana
We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast
cancer cells. www.biorxiv.org/content/10.1...

We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.
November 14, 2025 at 9:33 AM
Reposted by Irma Jayawardana
Hi all, check out our new preprint where we uncover:"Regulation of YAP activity by nuclear G-actin binding", www.biorxiv.org/cgi/content/...
#actin #YAP/TAZ #transcription #nucleus with help from Sonja-Verena Albers
‪@archaellum.bsky.social‬
Regulation of YAP activity by nuclear G-actin binding
The Yes-associated protein YAP belongs to the TEAD (TEA/ATTS domain) transcriptional co-activators that shuttle between cytoplasm and nuclear compartment. YAP and its paralog TAZ (transcriptional co-a...
www.biorxiv.org
July 31, 2025 at 6:34 AM