This method enables noninvasive PET imaging of atherosclerosis without using antibodies and may have potential for targeted drug delivery to atherosclerotic plaques.

👏 Congratulations to all the authors for this remarkable contribution to nanomedicine and molecular imaging! (4/4)

#Nanomedicine

The study shows that functionalized sphingomyelin solid lipid nanoparticles accumulate in atherosclerotic plaques, enabling binding of radiolabeled nanotracers for precise PET imaging.
In mice, a clear aortic arch signal appeared only in animals receiving the complete pretargeting strategy. (3/4)

In this work, the team introduces an innovative nanoparticle-to-nanoparticle pretargeted #PET imaging strategy for the noninvasive detection of #atherosclerosis — a fully nanomaterial-based approach that eliminates the need for antibodies as targeting agents. (2/4)

Segundo día de exposición por parte de los investigadores predoctorales del IQM 👏🏼

Daniel Cabrera Torrejón winner of the 2025 Chemistry Europe Prize to the best Flash Communication.