Gísli
@ipfdoc.bsky.social
Scientist, clinician, cyclist, Spurs, SFGiants
#CureIPF
https://www.imperial.ac.uk/mtw-centre-fibrosing-lung-disease/
Editor-In-Chief BMJ Open Respiratory Research
#CureIPF
https://www.imperial.ac.uk/mtw-centre-fibrosing-lung-disease/
Editor-In-Chief BMJ Open Respiratory Research
The most exciting papers of the year! Could these observers provide insights into the potential of immunotherapy in other conditions? 🤔
October 29, 2025 at 1:59 PM
The most exciting papers of the year! Could these observers provide insights into the potential of immunotherapy in other conditions? 🤔
This is a really great thread 🧵 about an important study using mixed methodology to understand a subject that rarely gets the attention it deserves. Kudos to the team @ucalgary.bsky.social guided by the brilliant @kerrijohannson.bsky.social
The Impact of Pulmonary Fibrosis on Sex and Sexual Function - A Multinational Mixed Methods Study
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
October 15, 2025 at 12:02 AM
This is a really great thread 🧵 about an important study using mixed methodology to understand a subject that rarely gets the attention it deserves. Kudos to the team @ucalgary.bsky.social guided by the brilliant @kerrijohannson.bsky.social
TETON-2 data looking good! 96ml of FVC ‘saved’ by inhaled treprostinil at 12 months. Devil will be in detail but all very promising.
September 28, 2025 at 12:36 PM
TETON-2 data looking good! 96ml of FVC ‘saved’ by inhaled treprostinil at 12 months. Devil will be in detail but all very promising.
youtu.be/zTs3PDEkB2w
Interesting story.
1) Brexit actually increased migration.
2) Students r source of UKs immigration‘problem’, likely due to our outstanding universities
3) Cumulative asylum seeker retention builds up
4) A ‘hostile environment’ might work but at what cost & for what impact? 😬
Interesting story.
1) Brexit actually increased migration.
2) Students r source of UKs immigration‘problem’, likely due to our outstanding universities
3) Cumulative asylum seeker retention builds up
4) A ‘hostile environment’ might work but at what cost & for what impact? 😬
UK immigration: What the numbers really show
YouTube video by Sky News
youtu.be
September 26, 2025 at 8:29 PM
youtu.be/zTs3PDEkB2w
Interesting story.
1) Brexit actually increased migration.
2) Students r source of UKs immigration‘problem’, likely due to our outstanding universities
3) Cumulative asylum seeker retention builds up
4) A ‘hostile environment’ might work but at what cost & for what impact? 😬
Interesting story.
1) Brexit actually increased migration.
2) Students r source of UKs immigration‘problem’, likely due to our outstanding universities
3) Cumulative asylum seeker retention builds up
4) A ‘hostile environment’ might work but at what cost & for what impact? 😬
Pogacar vs Vingegaard?
Alcaraz vs Sinner?
Tottenham vs Arsenal?
Giants vs Dodgers?
Nemesis vs motivation?
Alcaraz vs Sinner?
Tottenham vs Arsenal?
Giants vs Dodgers?
Nemesis vs motivation?
September 8, 2025 at 9:00 PM
Pogacar vs Vingegaard?
Alcaraz vs Sinner?
Tottenham vs Arsenal?
Giants vs Dodgers?
Nemesis vs motivation?
Alcaraz vs Sinner?
Tottenham vs Arsenal?
Giants vs Dodgers?
Nemesis vs motivation?
I think this is a great idea, might be tricky to operationalise.
The current system is breaking if not already broken.
Incentivises research fraud.
Will prevent people seeing the wood because of all the dodgy trees.
#LessIsMore
The current system is breaking if not already broken.
Incentivises research fraud.
Will prevent people seeing the wood because of all the dodgy trees.
#LessIsMore
PROPOSAL to address issue of publication flooding
Limit individuals to publishing a MAXIMUM of 10 articles/year
🌟 Quality > quantity
🌟 Forced to choose valuable work to which they have meaningfully contributed
🌟 Requires change in academic metrics
@benpatrickwill.bsky.social
@ipfdoc.bsky.social
Limit individuals to publishing a MAXIMUM of 10 articles/year
🌟 Quality > quantity
🌟 Forced to choose valuable work to which they have meaningfully contributed
🌟 Requires change in academic metrics
@benpatrickwill.bsky.social
@ipfdoc.bsky.social
a man in a suit and tie is standing in front of a door that says change is good
Alt: Captain Holt standing in front of a door that says change is good
media.tenor.com
September 7, 2025 at 8:25 PM
I think this is a great idea, might be tricky to operationalise.
The current system is breaking if not already broken.
Incentivises research fraud.
Will prevent people seeing the wood because of all the dodgy trees.
#LessIsMore
The current system is breaking if not already broken.
Incentivises research fraud.
Will prevent people seeing the wood because of all the dodgy trees.
#LessIsMore
This makes me sad (not altogether sure why), but I would like thank #DanielLevy for his hard work over last 25 yrs. The Stadium, European Glory Nights, Great teams, superstar players! 😍 There were some lows I’m sure but I don’t remember those. #COYS
September 4, 2025 at 5:24 PM
This makes me sad (not altogether sure why), but I would like thank #DanielLevy for his hard work over last 25 yrs. The Stadium, European Glory Nights, Great teams, superstar players! 😍 There were some lows I’m sure but I don’t remember those. #COYS
Phenomenal result! FIRST positive 52 week study of inhaled therapy in #IPF. Benefits were independent of background therapy! 🤩
Along with Nerandomilast this shows importance of cAMP/PDE4 pathways in fibrosis & opens door 4 other therapies targeting these pathways!
#FutureLooksBright #CureIPF
Along with Nerandomilast this shows importance of cAMP/PDE4 pathways in fibrosis & opens door 4 other therapies targeting these pathways!
#FutureLooksBright #CureIPF
TETON-2 phase 2 RCT of nebulized treprostinil for IPF 🫁
Positive trial 🗞️
Change in FVC at 52 weeks difference of 95.6mL (!), and 2* endpoints like K-BILD
@ipfdoc.bsky.social @kaminskimed.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
www.theglobeandmail.com/investing/ma...
Positive trial 🗞️
Change in FVC at 52 weeks difference of 95.6mL (!), and 2* endpoints like K-BILD
@ipfdoc.bsky.social @kaminskimed.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
www.theglobeandmail.com/investing/ma...
September 2, 2025 at 3:24 PM
Phenomenal result! FIRST positive 52 week study of inhaled therapy in #IPF. Benefits were independent of background therapy! 🤩
Along with Nerandomilast this shows importance of cAMP/PDE4 pathways in fibrosis & opens door 4 other therapies targeting these pathways!
#FutureLooksBright #CureIPF
Along with Nerandomilast this shows importance of cAMP/PDE4 pathways in fibrosis & opens door 4 other therapies targeting these pathways!
#FutureLooksBright #CureIPF
Reposted by Gísli
TETON-2 phase 2 RCT of nebulized treprostinil for IPF 🫁
Positive trial 🗞️
Change in FVC at 52 weeks difference of 95.6mL (!), and 2* endpoints like K-BILD
@ipfdoc.bsky.social @kaminskimed.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
www.theglobeandmail.com/investing/ma...
Positive trial 🗞️
Change in FVC at 52 weeks difference of 95.6mL (!), and 2* endpoints like K-BILD
@ipfdoc.bsky.social @kaminskimed.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
www.theglobeandmail.com/investing/ma...
September 2, 2025 at 2:56 PM
TETON-2 phase 2 RCT of nebulized treprostinil for IPF 🫁
Positive trial 🗞️
Change in FVC at 52 weeks difference of 95.6mL (!), and 2* endpoints like K-BILD
@ipfdoc.bsky.social @kaminskimed.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
www.theglobeandmail.com/investing/ma...
Positive trial 🗞️
Change in FVC at 52 weeks difference of 95.6mL (!), and 2* endpoints like K-BILD
@ipfdoc.bsky.social @kaminskimed.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
www.theglobeandmail.com/investing/ma...
I think there is no clinical need to update the classification, and I just can’t wait for the next update! 🥱
August 8, 2025 at 8:35 PM
I think there is no clinical need to update the classification, and I just can’t wait for the next update! 🥱
I’ve just been struck by how structurally (if not functionally) similar broccoli 🥦 is to the lungs 🫁! 😍🤣
August 8, 2025 at 8:29 PM
I’ve just been struck by how structurally (if not functionally) similar broccoli 🥦 is to the lungs 🫁! 😍🤣
Reposted by Gísli
This isn’t about Republicans or Democrats or anything to do with politics
This is about men exploiting and committing sexual violence against women and girls
THIS is the issue to bring to the forefront address
This is about men exploiting and committing sexual violence against women and girls
THIS is the issue to bring to the forefront address
July 23, 2025 at 3:57 PM
This isn’t about Republicans or Democrats or anything to do with politics
This is about men exploiting and committing sexual violence against women and girls
THIS is the issue to bring to the forefront address
This is about men exploiting and committing sexual violence against women and girls
THIS is the issue to bring to the forefront address
Reposted by Gísli
People’s brains aged faster during the COVID pandemic — even the uninfected @nature.com
www.nature.com/articles/d41...
@natcomms.nature.com @alirezamnk.bsky.social
@spmic-uon.bsky.social @ipfdoc.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/d41...
@natcomms.nature.com @alirezamnk.bsky.social
@spmic-uon.bsky.social @ipfdoc.bsky.social
www.nature.com/articles/s41...
July 22, 2025 at 8:33 PM
People’s brains aged faster during the COVID pandemic — even the uninfected @nature.com
www.nature.com/articles/d41...
@natcomms.nature.com @alirezamnk.bsky.social
@spmic-uon.bsky.social @ipfdoc.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/d41...
@natcomms.nature.com @alirezamnk.bsky.social
@spmic-uon.bsky.social @ipfdoc.bsky.social
www.nature.com/articles/s41...
Reposted by Gísli
1. Kevin Gross and I just posted a new science-of-science preprint.
This one explores the looming peer review crisis. As many of you know, it's becoming significantly more difficult for journal editors to find scholars willing to serve as peer reviewers for submitted manuscripts.
This one explores the looming peer review crisis. As many of you know, it's becoming significantly more difficult for journal editors to find scholars willing to serve as peer reviewers for submitted manuscripts.
Will anyone review this paper? Screening, sorting, and the feedback cycles that imperil peer review
Scholarly publishing relies on peer review to identify the best science. Yet finding willing and qualified reviewers to evaluate manuscripts has become an increasingly challenging task, possibly even ...
arxiv.org
July 16, 2025 at 3:13 AM
1. Kevin Gross and I just posted a new science-of-science preprint.
This one explores the looming peer review crisis. As many of you know, it's becoming significantly more difficult for journal editors to find scholars willing to serve as peer reviewers for submitted manuscripts.
This one explores the looming peer review crisis. As many of you know, it's becoming significantly more difficult for journal editors to find scholars willing to serve as peer reviewers for submitted manuscripts.
Reposted by Gísli
Incidence, Prevalence & Mortality of ILDs in Alberta, Canada
Derived, tested case definitions performed well, created a dataset of ILD. Incidence was stable, prevalence increased, mortality decreased for ILD & IPF sub-group
@kerrijohannson.bsky.social
@agrantorser.bsky.social
tinyurl.com/5n7x5w2h
Derived, tested case definitions performed well, created a dataset of ILD. Incidence was stable, prevalence increased, mortality decreased for ILD & IPF sub-group
@kerrijohannson.bsky.social
@agrantorser.bsky.social
tinyurl.com/5n7x5w2h
July 16, 2025 at 4:26 PM
Incidence, Prevalence & Mortality of ILDs in Alberta, Canada
Derived, tested case definitions performed well, created a dataset of ILD. Incidence was stable, prevalence increased, mortality decreased for ILD & IPF sub-group
@kerrijohannson.bsky.social
@agrantorser.bsky.social
tinyurl.com/5n7x5w2h
Derived, tested case definitions performed well, created a dataset of ILD. Incidence was stable, prevalence increased, mortality decreased for ILD & IPF sub-group
@kerrijohannson.bsky.social
@agrantorser.bsky.social
tinyurl.com/5n7x5w2h
Reposted by Gísli
🎙️ Just published a #NEW episode of Out of the Blue: An AJRCCM Podcast: Approach to the Evaluation and Management of Interstitial Lung Abnormalities
@atscommunity.bsky.social #medsky
Have a listen: outoftheblue.transistor.fm
@atscommunity.bsky.social #medsky
Have a listen: outoftheblue.transistor.fm
Out of the Blue: An AJRCCM Podcast
The Out of the Blue podcast takes you out of the pages of the American Journal of Respiratory and Critical Care Medicine and into the minds of the most brilliant researchers in the fields of respirato...
outoftheblue.transistor.fm
July 17, 2025 at 3:15 PM
🎙️ Just published a #NEW episode of Out of the Blue: An AJRCCM Podcast: Approach to the Evaluation and Management of Interstitial Lung Abnormalities
@atscommunity.bsky.social #medsky
Have a listen: outoftheblue.transistor.fm
@atscommunity.bsky.social #medsky
Have a listen: outoftheblue.transistor.fm
July 14, 2025 at 12:30 PM
Great article from @theguardian.com which nicely summarises a real problem. As I’m fond of saying ‘if you are looking for a needle in a haystack, stop adding more hay!’
Thanks for sharing @kerrijohannson.bsky.social @bmj.com
Thanks for sharing @kerrijohannson.bsky.social @bmj.com
Tips for academic sustainability:
Only review for journals you know
Do not submit to predatory journals
Do NOT contribute to this crap
Stop thinking about 'getting papers' and think about 'advancing your field' - this needs to change for promotion and merit
www.theguardian.com/science/2025...
Only review for journals you know
Do not submit to predatory journals
Do NOT contribute to this crap
Stop thinking about 'getting papers' and think about 'advancing your field' - this needs to change for promotion and merit
www.theguardian.com/science/2025...
Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published
Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention
www.theguardian.com
July 13, 2025 at 5:32 PM
Great article from @theguardian.com which nicely summarises a real problem. As I’m fond of saying ‘if you are looking for a needle in a haystack, stop adding more hay!’
Thanks for sharing @kerrijohannson.bsky.social @bmj.com
Thanks for sharing @kerrijohannson.bsky.social @bmj.com
Reposted by Gísli
Tips for academic sustainability:
Only review for journals you know
Do not submit to predatory journals
Do NOT contribute to this crap
Stop thinking about 'getting papers' and think about 'advancing your field' - this needs to change for promotion and merit
www.theguardian.com/science/2025...
Only review for journals you know
Do not submit to predatory journals
Do NOT contribute to this crap
Stop thinking about 'getting papers' and think about 'advancing your field' - this needs to change for promotion and merit
www.theguardian.com/science/2025...
Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published
Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention
www.theguardian.com
July 13, 2025 at 5:06 PM
Tips for academic sustainability:
Only review for journals you know
Do not submit to predatory journals
Do NOT contribute to this crap
Stop thinking about 'getting papers' and think about 'advancing your field' - this needs to change for promotion and merit
www.theguardian.com/science/2025...
Only review for journals you know
Do not submit to predatory journals
Do NOT contribute to this crap
Stop thinking about 'getting papers' and think about 'advancing your field' - this needs to change for promotion and merit
www.theguardian.com/science/2025...
How many people ask permission from proposed reviewer when they ‘recommend’ a reviewer for submitted publication? Fairly standard when requesting professional reference and might reduced the number of declined reviews from ‘recommended reviewers’?
#AnswersOnAPostcard
#AnswersOnAPostcard
July 10, 2025 at 4:59 PM
How many people ask permission from proposed reviewer when they ‘recommend’ a reviewer for submitted publication? Fairly standard when requesting professional reference and might reduced the number of declined reviews from ‘recommended reviewers’?
#AnswersOnAPostcard
#AnswersOnAPostcard
NEWSFLASH, any reviewer for BMJOpenRespRes gets a 25% discount on the APC for manuscripts submitted to BMJOpenRespRes within 12 months.
There maybe further positive moves in future #SmallSteps. #GettingThere 🙏🙏
There maybe further positive moves in future #SmallSteps. #GettingThere 🙏🙏
July 8, 2025 at 3:43 PM
NEWSFLASH, any reviewer for BMJOpenRespRes gets a 25% discount on the APC for manuscripts submitted to BMJOpenRespRes within 12 months.
There maybe further positive moves in future #SmallSteps. #GettingThere 🙏🙏
There maybe further positive moves in future #SmallSteps. #GettingThere 🙏🙏
Wow! 🤩 Some really important messages in here!
The burden of ILD is higher than thought AND rising.
Burden in rural communities higher than cities! 🤔?🌾🚜🐤
Mortality 📉 suggests Dx and Mx improving 🥳
Kudos to @kerrijohannson.bsky.social & team!
The burden of ILD is higher than thought AND rising.
Burden in rural communities higher than cities! 🤔?🌾🚜🐤
Mortality 📉 suggests Dx and Mx improving 🥳
Kudos to @kerrijohannson.bsky.social & team!
Incidence, Prevalence, and Mortality of Interstitial Lung Diseases in Alberta, Canada: A Population-based Study
www.atsjournals.org/doi/suppl/10...
🧵👇
📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.
www.atsjournals.org/doi/suppl/10...
🧵👇
📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.
July 5, 2025 at 1:14 PM
Wow! 🤩 Some really important messages in here!
The burden of ILD is higher than thought AND rising.
Burden in rural communities higher than cities! 🤔?🌾🚜🐤
Mortality 📉 suggests Dx and Mx improving 🥳
Kudos to @kerrijohannson.bsky.social & team!
The burden of ILD is higher than thought AND rising.
Burden in rural communities higher than cities! 🤔?🌾🚜🐤
Mortality 📉 suggests Dx and Mx improving 🥳
Kudos to @kerrijohannson.bsky.social & team!
Reposted by Gísli
Important!
A population based study of trends in incidence, prevalence, mortality of ILD over 10 yrs.
Good news: Mortality ⬇️.
Expected news: Incidence unchanged, Prevalence ⬆️
Important News: there are a lot of ILD patients
👏🏼 Drs Johannson, Fisher & team!!!
www.atsjournals.org/doi/full/10....
A population based study of trends in incidence, prevalence, mortality of ILD over 10 yrs.
Good news: Mortality ⬇️.
Expected news: Incidence unchanged, Prevalence ⬆️
Important News: there are a lot of ILD patients
👏🏼 Drs Johannson, Fisher & team!!!
www.atsjournals.org/doi/full/10....
July 4, 2025 at 7:26 PM
Important!
A population based study of trends in incidence, prevalence, mortality of ILD over 10 yrs.
Good news: Mortality ⬇️.
Expected news: Incidence unchanged, Prevalence ⬆️
Important News: there are a lot of ILD patients
👏🏼 Drs Johannson, Fisher & team!!!
www.atsjournals.org/doi/full/10....
A population based study of trends in incidence, prevalence, mortality of ILD over 10 yrs.
Good news: Mortality ⬇️.
Expected news: Incidence unchanged, Prevalence ⬆️
Important News: there are a lot of ILD patients
👏🏼 Drs Johannson, Fisher & team!!!
www.atsjournals.org/doi/full/10....
Reposted by Gísli
Kudos to the amazing team from University of Calgary Centre for Health Informatics, support from the AB ILD UHF grant (without whom this would not be possible), and collaborators including @agrantorser.bsky.social Dr. Jolene Fisher & @annalsats.bsky.social for appreciating the value of this work 💪🫁😊
a blue and white penguin says thank you
ALT: a blue and white penguin says thank you
media.tenor.com
July 4, 2025 at 2:35 PM
Kudos to the amazing team from University of Calgary Centre for Health Informatics, support from the AB ILD UHF grant (without whom this would not be possible), and collaborators including @agrantorser.bsky.social Dr. Jolene Fisher & @annalsats.bsky.social for appreciating the value of this work 💪🫁😊
Reposted by Gísli
Incidence, Prevalence, and Mortality of Interstitial Lung Diseases in Alberta, Canada: A Population-based Study
www.atsjournals.org/doi/suppl/10...
🧵👇
📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.
www.atsjournals.org/doi/suppl/10...
🧵👇
📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.
July 4, 2025 at 2:35 PM
Incidence, Prevalence, and Mortality of Interstitial Lung Diseases in Alberta, Canada: A Population-based Study
www.atsjournals.org/doi/suppl/10...
🧵👇
📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.
www.atsjournals.org/doi/suppl/10...
🧵👇
📣 TL:DR Incidence stable, prevalence rising, improved survival for ILD & IPF over 10 years.
Numbers much higher than prior reports for ILD & IPF.