Ioannis Parodis
@ioannisparodis.bsky.social
MD PhD | Associate Professor of Rheumatology at Karolinska Institutet with a passion for #lupus and #autoimmunity
Reposted by Ioannis Parodis
Lupus nephritis is a type of immune-mediated glomerulonephritis and a serious complication of systemic lupus erythematosus that can affect up to 60% of patients with this condition.
https://www.nature.c...
https://www.nature.c...
October 1, 2025 at 7:00 PM
Lupus nephritis is a type of immune-mediated glomerulonephritis and a serious complication of systemic lupus erythematosus that can affect up to 60% of patients with this condition.
https://www.nature.c...
https://www.nature.c...
Reposted by Ioannis Parodis
Kidney biopsy findings guide lupus nephritis management and treatment is tailored to inflammation severity and chronic damage, incorporating immunosuppressive and adjunctive measures to protect renal function.
https://www.nature.c...
https://www.nature.c...
September 29, 2025 at 6:56 AM
Kidney biopsy findings guide lupus nephritis management and treatment is tailored to inflammation severity and chronic damage, incorporating immunosuppressive and adjunctive measures to protect renal function.
https://www.nature.c...
https://www.nature.c...
Reposted by Ioannis Parodis
Comorbid conditions of lupus nephritis and adverse events associated with its treatment, for example infections, cardiovascular issues, and osteoporosis, require active management according to guidelines.
https://www.nature.c...
https://www.nature.c...
September 30, 2025 at 5:58 AM
Comorbid conditions of lupus nephritis and adverse events associated with its treatment, for example infections, cardiovascular issues, and osteoporosis, require active management according to guidelines.
https://www.nature.c...
https://www.nature.c...
Reposted by Ioannis Parodis
Our NEW Primer on Lupus nephritis is live today! By Parodis, Rovin, Tektonidou, Anders, Malvar, Mok & Mohan. Check it out here:
Lupus nephritis - Nature Reviews Disease Primers
Lupus nephritis is an autoimmune-mediated glomerulonephritis and a serious complication of systemic lupus erythematosus. In this Primer, Parodis and colleagues describe the epidemiology and pathophysiology of this disease, discuss current diagnosis and management, and highlight the effects on patient quality of life as well as future areas of research.
www.nature.com
September 25, 2025 at 8:57 AM
Our NEW Primer on Lupus nephritis is live today! By Parodis, Rovin, Tektonidou, Anders, Malvar, Mok & Mohan. Check it out here:
Reposted by Ioannis Parodis
Get Primed on Lupus nephritis with our NEW PrimeView! FREE to download this week! https://www.nature.c... #medsky
September 25, 2025 at 6:00 PM
Get Primed on Lupus nephritis with our NEW PrimeView! FREE to download this week! https://www.nature.c... #medsky
Reposted by Ioannis Parodis
Adaptive immune cells in lupus nephritis are activated through various pathways, including via B cell and T cell receptors, and cytokine signalling, with multiple therapeutic targets identified for potential intervention.
https://www.nature.c...
https://www.nature.c...
September 26, 2025 at 8:41 AM
Adaptive immune cells in lupus nephritis are activated through various pathways, including via B cell and T cell receptors, and cytokine signalling, with multiple therapeutic targets identified for potential intervention.
https://www.nature.c...
https://www.nature.c...
Reposted by Ioannis Parodis
Calcineurin inhibitors target shared signalling pathways in lymphocytes and podocytes, reducing cytokine and autoantibody production and preventing podocyte loss and glomerulosclerosis in lupus nephritis.
https://www.nature.c...
https://www.nature.c...
September 27, 2025 at 8:45 AM
Calcineurin inhibitors target shared signalling pathways in lymphocytes and podocytes, reducing cytokine and autoantibody production and preventing podocyte loss and glomerulosclerosis in lupus nephritis.
https://www.nature.c...
https://www.nature.c...
Reposted by Ioannis Parodis
Both immune and non-immune factors contribute to proteinuria in lupus nephritis, influenced by genetic, intrinsic, and extrinsic factors, leading to chronic kidney disease progression.
https://www.nature.c...
https://www.nature.c...
September 28, 2025 at 6:50 AM
Both immune and non-immune factors contribute to proteinuria in lupus nephritis, influenced by genetic, intrinsic, and extrinsic factors, leading to chronic kidney disease progression.
https://www.nature.c...
https://www.nature.c...
Happy to share our recent work:
www.sciencedirect.com/science/arti...
Still a lot we don’t know about #lupus
www.sciencedirect.com/science/arti...
Still a lot we don’t know about #lupus
Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN...
This study aimed to identify and validate novel autoantibodies that reflect global and organ-specific disease activity in systemic lupus erythematosus…
www.sciencedirect.com
May 14, 2025 at 7:33 PM
Happy to share our recent work:
www.sciencedirect.com/science/arti...
Still a lot we don’t know about #lupus
www.sciencedirect.com/science/arti...
Still a lot we don’t know about #lupus
Reposted by Ioannis Parodis
📍Estamos en Viena en #RheumaPreg25
Nuestra vicepresidenta trae la voz de pacientes al panel sobre los desafíos en la investigación en embarazo y lactancia con @lauraandreoli.bsky.social, Klara Rosta @rheproat.bsky.social, @karenschreiber.bsky.social Judit Sandor y @nelson-piercy.bsky.social
Nuestra vicepresidenta trae la voz de pacientes al panel sobre los desafíos en la investigación en embarazo y lactancia con @lauraandreoli.bsky.social, Klara Rosta @rheproat.bsky.social, @karenschreiber.bsky.social Judit Sandor y @nelson-piercy.bsky.social
May 9, 2025 at 8:45 AM
📍Estamos en Viena en #RheumaPreg25
Nuestra vicepresidenta trae la voz de pacientes al panel sobre los desafíos en la investigación en embarazo y lactancia con @lauraandreoli.bsky.social, Klara Rosta @rheproat.bsky.social, @karenschreiber.bsky.social Judit Sandor y @nelson-piercy.bsky.social
Nuestra vicepresidenta trae la voz de pacientes al panel sobre los desafíos en la investigación en embarazo y lactancia con @lauraandreoli.bsky.social, Klara Rosta @rheproat.bsky.social, @karenschreiber.bsky.social Judit Sandor y @nelson-piercy.bsky.social
Reposted by Ioannis Parodis
Delighted to share our review on #HealthDisparities in #rheumatology management in #JointBoneSpine.
Here, we discuss aspects such as social, societal & structural barriers to care and optimal management in #RMDs, & how we may tackle them.
🔗 www.sciencedirect.com/science/arti...
Here, we discuss aspects such as social, societal & structural barriers to care and optimal management in #RMDs, & how we may tackle them.
🔗 www.sciencedirect.com/science/arti...
April 12, 2025 at 3:32 PM
Delighted to share our review on #HealthDisparities in #rheumatology management in #JointBoneSpine.
Here, we discuss aspects such as social, societal & structural barriers to care and optimal management in #RMDs, & how we may tackle them.
🔗 www.sciencedirect.com/science/arti...
Here, we discuss aspects such as social, societal & structural barriers to care and optimal management in #RMDs, & how we may tackle them.
🔗 www.sciencedirect.com/science/arti...
Reposted by Ioannis Parodis
Genetic Testing in Biopsy-Confirmed Kidney Disease
www.kidneymedicinejournal.org
April 5, 2025 at 3:52 PM
Genetic Testing in Biopsy-Confirmed Kidney Disease
Reposted by Ioannis Parodis
AI for Education: Trends and Insights
"the shift from perception to cognition, the transition from generalized to personalized learning, and the rise of multimodal systems"
www.sciencedirect.com/science/arti...
"the shift from perception to cognition, the transition from generalized to personalized learning, and the rise of multimodal systems"
www.sciencedirect.com/science/arti...
March 30, 2025 at 6:00 PM
AI for Education: Trends and Insights
"the shift from perception to cognition, the transition from generalized to personalized learning, and the rise of multimodal systems"
www.sciencedirect.com/science/arti...
"the shift from perception to cognition, the transition from generalized to personalized learning, and the rise of multimodal systems"
www.sciencedirect.com/science/arti...
Happy New Year! 🎆
December 31, 2024 at 5:34 PM
Happy New Year! 🎆
Time is kidney!
Timely diagnosis of #lupusnephritis with a #kidneybiopsy and prompt initiation of immune and non-immune treatment to dampen inflammation and protect the kidney tissue is crucial.
#RheumSky #MedSky #lupus
Timely diagnosis of #lupusnephritis with a #kidneybiopsy and prompt initiation of immune and non-immune treatment to dampen inflammation and protect the kidney tissue is crucial.
#RheumSky #MedSky #lupus
December 15, 2024 at 3:41 PM
Time is kidney!
Timely diagnosis of #lupusnephritis with a #kidneybiopsy and prompt initiation of immune and non-immune treatment to dampen inflammation and protect the kidney tissue is crucial.
#RheumSky #MedSky #lupus
Timely diagnosis of #lupusnephritis with a #kidneybiopsy and prompt initiation of immune and non-immune treatment to dampen inflammation and protect the kidney tissue is crucial.
#RheumSky #MedSky #lupus