Cancer Screening & Prevention Research Group
@imperial-csprg.bsky.social
@imperialcollegeldn.bsky.social gastrointestinal cancer research group. Led by Professor Amanda Cross & Dr Gwen Murphy @imperialsandc.bsky.social.
Funded by @cancerresearchuk.org & @nihr.bsky.social.
https://csprg.org.uk/
https://tinyurl.com/8v6y7zms
Funded by @cancerresearchuk.org & @nihr.bsky.social.
https://csprg.org.uk/
https://tinyurl.com/8v6y7zms
Our @imperialcollegeldn.bsky.social colleagues were gathered this week for @who.int IARC EPIC annual meeting to share and discover the wide range of #cancerresearch studies being carried out across this important cohort.
@wcrf.org
@wcrf.org
October 8, 2025 at 1:09 PM
Our @imperialcollegeldn.bsky.social colleagues were gathered this week for @who.int IARC EPIC annual meeting to share and discover the wide range of #cancerresearch studies being carried out across this important cohort.
@wcrf.org
@wcrf.org
Also at EPIC is @imperialmed.bsky.social
#PhD candidate Rawan Maawadh (supervisor Prof Amanda Cross) giving a talk on 'Proteomic Signatures of #Obesity and their Associations with #ColorectalCancer in a Case-Cohort Study in EPIC'
#PhD candidate Rawan Maawadh (supervisor Prof Amanda Cross) giving a talk on 'Proteomic Signatures of #Obesity and their Associations with #ColorectalCancer in a Case-Cohort Study in EPIC'
October 7, 2025 at 3:00 PM
Also at EPIC is @imperialmed.bsky.social
#PhD candidate Rawan Maawadh (supervisor Prof Amanda Cross) giving a talk on 'Proteomic Signatures of #Obesity and their Associations with #ColorectalCancer in a Case-Cohort Study in EPIC'
#PhD candidate Rawan Maawadh (supervisor Prof Amanda Cross) giving a talk on 'Proteomic Signatures of #Obesity and their Associations with #ColorectalCancer in a Case-Cohort Study in EPIC'
Our @imperialmed.bsky.social #PhD candidate Nefeli Taravira is at Rome today for @who.int IARC EPIC annual meeting presenting her research on 'The impact of #education, #smoking and #alcohol on oesophageal squamous cell #carcinoma risk in the EPIC cohort'
October 7, 2025 at 2:56 PM
Our @imperialmed.bsky.social #PhD candidate Nefeli Taravira is at Rome today for @who.int IARC EPIC annual meeting presenting her research on 'The impact of #education, #smoking and #alcohol on oesophageal squamous cell #carcinoma risk in the EPIC cohort'
Congrats to @imperialsandc.bsky.social postdoc Dr Rhea Harewood on receiving the @cancerresearchuk.org Bridge to Academic Leadership Award! This award will support Rhea in building skills to pursue independent research & transition to group leadership in the field of proximal bowel cancer aetiology
September 23, 2025 at 2:57 PM
Congrats to @imperialsandc.bsky.social postdoc Dr Rhea Harewood on receiving the @cancerresearchuk.org Bridge to Academic Leadership Award! This award will support Rhea in building skills to pursue independent research & transition to group leadership in the field of proximal bowel cancer aetiology
Thrilled to share that Fangqing Li has been awarded a China Scholarship Council @imperialcollegeldn.bsky.social Scholarship!
She'll rejoin CSPRG in July as a fully funded PhD student, focusing on early-onset colorectal cancer.
Welcome back Fangqing!
#PhD #CancerResearch @imperialsandc.bsky.social
She'll rejoin CSPRG in July as a fully funded PhD student, focusing on early-onset colorectal cancer.
Welcome back Fangqing!
#PhD #CancerResearch @imperialsandc.bsky.social
July 3, 2025 at 12:43 PM
Thrilled to share that Fangqing Li has been awarded a China Scholarship Council @imperialcollegeldn.bsky.social Scholarship!
She'll rejoin CSPRG in July as a fully funded PhD student, focusing on early-onset colorectal cancer.
Welcome back Fangqing!
#PhD #CancerResearch @imperialsandc.bsky.social
She'll rejoin CSPRG in July as a fully funded PhD student, focusing on early-onset colorectal cancer.
Welcome back Fangqing!
#PhD #CancerResearch @imperialsandc.bsky.social
@imperialbrc.bsky.social-funded Dr Rhea Harewood & Kelly Gleason led a great #BowelCancerAwareness online session, supported by @imperialsandc.bsky.social, with Harrow THCOGIC Church members last week!
They covered bowel cancer causes, public involvement in research, & Rhea's future research plans
They covered bowel cancer causes, public involvement in research, & Rhea's future research plans
July 1, 2025 at 10:25 AM
@imperialbrc.bsky.social-funded Dr Rhea Harewood & Kelly Gleason led a great #BowelCancerAwareness online session, supported by @imperialsandc.bsky.social, with Harrow THCOGIC Church members last week!
They covered bowel cancer causes, public involvement in research, & Rhea's future research plans
They covered bowel cancer causes, public involvement in research, & Rhea's future research plans
A huge thank you to the 3 brilliant speakers (& their supportive colleagues) from @imperialnhs.bsky.social, @imperialsandc.bsky.social who joined Dr Harewood for a PPI session with 58 EKTA Harrow community members
Valuable discussions had on breast & prostate cancer awareness & current research!
Valuable discussions had on breast & prostate cancer awareness & current research!
June 30, 2025 at 9:09 AM
A huge thank you to the 3 brilliant speakers (& their supportive colleagues) from @imperialnhs.bsky.social, @imperialsandc.bsky.social who joined Dr Harewood for a PPI session with 58 EKTA Harrow community members
Valuable discussions had on breast & prostate cancer awareness & current research!
Valuable discussions had on breast & prostate cancer awareness & current research!
More @cancerresearchuk.org #PrevConf25 final day action
✅Heavyweight academics slug it out over GLP1 agonists importance (or not) for #cancerprevention
✅Prof Karen Brown weighs in on drugs for precision cancer prevention
www.cancerresearchuk.org/funding-for-...
✅Heavyweight academics slug it out over GLP1 agonists importance (or not) for #cancerprevention
✅Prof Karen Brown weighs in on drugs for precision cancer prevention
www.cancerresearchuk.org/funding-for-...
June 27, 2025 at 3:55 PM
More @cancerresearchuk.org #PrevConf25 final day action
✅Heavyweight academics slug it out over GLP1 agonists importance (or not) for #cancerprevention
✅Prof Karen Brown weighs in on drugs for precision cancer prevention
www.cancerresearchuk.org/funding-for-...
✅Heavyweight academics slug it out over GLP1 agonists importance (or not) for #cancerprevention
✅Prof Karen Brown weighs in on drugs for precision cancer prevention
www.cancerresearchuk.org/funding-for-...
Busy week catching up with all the latest in #cancerprevention at @cancerresearchuk.org #PrevConf25
✅Pressing agenda
✅Brilliant talks
✅Thought-provoking debates
✅Opportune catch-up with colleagues & collaborators
www.cancerresearchuk.org/funding-for-...
✅Pressing agenda
✅Brilliant talks
✅Thought-provoking debates
✅Opportune catch-up with colleagues & collaborators
www.cancerresearchuk.org/funding-for-...
June 27, 2025 at 10:07 AM
Busy week catching up with all the latest in #cancerprevention at @cancerresearchuk.org #PrevConf25
✅Pressing agenda
✅Brilliant talks
✅Thought-provoking debates
✅Opportune catch-up with colleagues & collaborators
www.cancerresearchuk.org/funding-for-...
✅Pressing agenda
✅Brilliant talks
✅Thought-provoking debates
✅Opportune catch-up with colleagues & collaborators
www.cancerresearchuk.org/funding-for-...
This is the first study to show an association between distal polyp characteristics & long-term proximal colon cancer risk, helping to inform who might benefit from colonoscopy, and providing evidence for future updates of post-polypectomy surveillance guidelines.
Read it here: t.co/P6P4wA8zxF
Read it here: t.co/P6P4wA8zxF
June 24, 2025 at 9:27 AM
This is the first study to show an association between distal polyp characteristics & long-term proximal colon cancer risk, helping to inform who might benefit from colonoscopy, and providing evidence for future updates of post-polypectomy surveillance guidelines.
Read it here: t.co/P6P4wA8zxF
Read it here: t.co/P6P4wA8zxF
New analyses of #UKFSST data identify distal polyp characteristics associated with future proximal colon cancer risk.
Funders: @cancerresearchuk.org @nihr.bsky.social
Authors: R Harewood, K Wooldrage, E Robbins, J Kinross, C Wagner & AJ Cross
Journal: @bmj.com Open Gastroenterology
Funders: @cancerresearchuk.org @nihr.bsky.social
Authors: R Harewood, K Wooldrage, E Robbins, J Kinross, C Wagner & AJ Cross
Journal: @bmj.com Open Gastroenterology
June 24, 2025 at 9:26 AM
New analyses of #UKFSST data identify distal polyp characteristics associated with future proximal colon cancer risk.
Funders: @cancerresearchuk.org @nihr.bsky.social
Authors: R Harewood, K Wooldrage, E Robbins, J Kinross, C Wagner & AJ Cross
Journal: @bmj.com Open Gastroenterology
Funders: @cancerresearchuk.org @nihr.bsky.social
Authors: R Harewood, K Wooldrage, E Robbins, J Kinross, C Wagner & AJ Cross
Journal: @bmj.com Open Gastroenterology
New paper alert!
Larger or high-grade dysplastic distal adenomas found on flexi-sig screening are associated with ⬆️ risk of future proximal colon cancer.
No associations for number or histology of distal adenomas or any distal hyperplastic polyp characteristics
@bmj.com OpenGastro
t.co/P6P4wA8zxF
Larger or high-grade dysplastic distal adenomas found on flexi-sig screening are associated with ⬆️ risk of future proximal colon cancer.
No associations for number or histology of distal adenomas or any distal hyperplastic polyp characteristics
@bmj.com OpenGastro
t.co/P6P4wA8zxF
June 24, 2025 at 9:23 AM
New paper alert!
Larger or high-grade dysplastic distal adenomas found on flexi-sig screening are associated with ⬆️ risk of future proximal colon cancer.
No associations for number or histology of distal adenomas or any distal hyperplastic polyp characteristics
@bmj.com OpenGastro
t.co/P6P4wA8zxF
Larger or high-grade dysplastic distal adenomas found on flexi-sig screening are associated with ⬆️ risk of future proximal colon cancer.
No associations for number or histology of distal adenomas or any distal hyperplastic polyp characteristics
@bmj.com OpenGastro
t.co/P6P4wA8zxF
We took a break from the office to celebrate the successful PhD vivas of both Emma and Sharon with a sunny picnic! It was great to have the opportunity to mark this achievement as a group, congratulations to you both!
#PhDone
#PhDone
May 29, 2025 at 2:22 PM
We took a break from the office to celebrate the successful PhD vivas of both Emma and Sharon with a sunny picnic! It was great to have the opportunity to mark this achievement as a group, congratulations to you both!
#PhDone
#PhDone
Thanks @qubelfastofficial.bsky.social @helencolemanqub.bsky.social for inviting Amanda J Cross to give the Charlotte Jackson Gift Lecture today! A great opportunity to share our @cancerresearchuk.org funded work on #BowelCancer early detection & how our findings are influencing policy & patient care
May 22, 2025 at 3:28 PM
Thanks @qubelfastofficial.bsky.social @helencolemanqub.bsky.social for inviting Amanda J Cross to give the Charlotte Jackson Gift Lecture today! A great opportunity to share our @cancerresearchuk.org funded work on #BowelCancer early detection & how our findings are influencing policy & patient care
Post doc Dr Rhea Harewood sharing #BowelCancerAwareness at a community outreach event with the Harrow THCOGIC church.
The group discussed how #BowelCancer is caused, how we can screen to find it earlier and how to improve public involvement in bowel cancer research
#EDI #CancerResearch
The group discussed how #BowelCancer is caused, how we can screen to find it earlier and how to improve public involvement in bowel cancer research
#EDI #CancerResearch
April 24, 2025 at 10:25 AM
Post doc Dr Rhea Harewood sharing #BowelCancerAwareness at a community outreach event with the Harrow THCOGIC church.
The group discussed how #BowelCancer is caused, how we can screen to find it earlier and how to improve public involvement in bowel cancer research
#EDI #CancerResearch
The group discussed how #BowelCancer is caused, how we can screen to find it earlier and how to improve public involvement in bowel cancer research
#EDI #CancerResearch
Improving involvement of EDI groups in #BowelCancer research is essential to make medical research more equitable
Rhea Harewood & Kelly Gleason collaborated with the Asian Women Cancer Group to hear their opinions on Rhea's future bowel #CancerResearch plans!
#BowelCancerAwareness
Rhea Harewood & Kelly Gleason collaborated with the Asian Women Cancer Group to hear their opinions on Rhea's future bowel #CancerResearch plans!
#BowelCancerAwareness
April 23, 2025 at 1:25 PM
Improving involvement of EDI groups in #BowelCancer research is essential to make medical research more equitable
Rhea Harewood & Kelly Gleason collaborated with the Asian Women Cancer Group to hear their opinions on Rhea's future bowel #CancerResearch plans!
#BowelCancerAwareness
Rhea Harewood & Kelly Gleason collaborated with the Asian Women Cancer Group to hear their opinions on Rhea's future bowel #CancerResearch plans!
#BowelCancerAwareness
7/8
Conclusion
Pts with high-risk findings at both baseline & SC1 needed a second surveillance colonoscopy, whereas those with low-risk findings at SC1 did not, regardless of their baseline findings.
We couldn't draw conclusions for the LR-HR group due to limited CRC cases.
Conclusion
Pts with high-risk findings at both baseline & SC1 needed a second surveillance colonoscopy, whereas those with low-risk findings at SC1 did not, regardless of their baseline findings.
We couldn't draw conclusions for the LR-HR group due to limited CRC cases.
April 7, 2025 at 9:30 AM
7/8
Conclusion
Pts with high-risk findings at both baseline & SC1 needed a second surveillance colonoscopy, whereas those with low-risk findings at SC1 did not, regardless of their baseline findings.
We couldn't draw conclusions for the LR-HR group due to limited CRC cases.
Conclusion
Pts with high-risk findings at both baseline & SC1 needed a second surveillance colonoscopy, whereas those with low-risk findings at SC1 did not, regardless of their baseline findings.
We couldn't draw conclusions for the LR-HR group due to limited CRC cases.
6/8
Findings:
Compared to the general population, CRC incidence after SC1 was:
▪️ ~0.5 times lower in the LR-LR group
▪️ - Non-significantly different in the HR-LR or LR-HR groups, although the 95%CI for the LR-HR group was wide due to few CRC cases
▪️ - ~3 times higher in the HR-HR group
Findings:
Compared to the general population, CRC incidence after SC1 was:
▪️ ~0.5 times lower in the LR-LR group
▪️ - Non-significantly different in the HR-LR or LR-HR groups, although the 95%CI for the LR-HR group was wide due to few CRC cases
▪️ - ~3 times higher in the HR-HR group
April 7, 2025 at 9:30 AM
6/8
Findings:
Compared to the general population, CRC incidence after SC1 was:
▪️ ~0.5 times lower in the LR-LR group
▪️ - Non-significantly different in the HR-LR or LR-HR groups, although the 95%CI for the LR-HR group was wide due to few CRC cases
▪️ - ~3 times higher in the HR-HR group
Findings:
Compared to the general population, CRC incidence after SC1 was:
▪️ ~0.5 times lower in the LR-LR group
▪️ - Non-significantly different in the HR-LR or LR-HR groups, although the 95%CI for the LR-HR group was wide due to few CRC cases
▪️ - ~3 times higher in the HR-HR group
4/8
Methods
10,508 pts were split into 4 groups defined by their findings at baseline & at SC1
- ‘Low-risk, low-risk’ (LR-LR)
- ‘High-risk, low-risk’ (HR-LR)
- ‘Low-risk, high-risk’ (LR-HR)
- ‘High-risk, high-risk’ (HR-HR)
Methods
10,508 pts were split into 4 groups defined by their findings at baseline & at SC1
- ‘Low-risk, low-risk’ (LR-LR)
- ‘High-risk, low-risk’ (HR-LR)
- ‘Low-risk, high-risk’ (LR-HR)
- ‘High-risk, high-risk’ (HR-HR)
April 7, 2025 at 9:30 AM
4/8
Methods
10,508 pts were split into 4 groups defined by their findings at baseline & at SC1
- ‘Low-risk, low-risk’ (LR-LR)
- ‘High-risk, low-risk’ (HR-LR)
- ‘Low-risk, high-risk’ (LR-HR)
- ‘High-risk, high-risk’ (HR-HR)
Methods
10,508 pts were split into 4 groups defined by their findings at baseline & at SC1
- ‘Low-risk, low-risk’ (LR-LR)
- ‘High-risk, low-risk’ (HR-LR)
- ‘Low-risk, high-risk’ (LR-HR)
- ‘High-risk, high-risk’ (HR-HR)
2/8
What
A retrospective, cohort analysis of pts who underwent baseline colonoscopy with polyp removal & had ≥1 check-up colonoscopies (‘post-polypectomy surveillance’).
Authors: E Robbins, K Wooldrage, M Rutter, A Veitch & A J Cross
Funding: @cancerresearchuk.org @nihr.bsky.social
What
A retrospective, cohort analysis of pts who underwent baseline colonoscopy with polyp removal & had ≥1 check-up colonoscopies (‘post-polypectomy surveillance’).
Authors: E Robbins, K Wooldrage, M Rutter, A Veitch & A J Cross
Funding: @cancerresearchuk.org @nihr.bsky.social
April 7, 2025 at 9:30 AM
2/8
What
A retrospective, cohort analysis of pts who underwent baseline colonoscopy with polyp removal & had ≥1 check-up colonoscopies (‘post-polypectomy surveillance’).
Authors: E Robbins, K Wooldrage, M Rutter, A Veitch & A J Cross
Funding: @cancerresearchuk.org @nihr.bsky.social
What
A retrospective, cohort analysis of pts who underwent baseline colonoscopy with polyp removal & had ≥1 check-up colonoscopies (‘post-polypectomy surveillance’).
Authors: E Robbins, K Wooldrage, M Rutter, A Veitch & A J Cross
Funding: @cancerresearchuk.org @nihr.bsky.social
1/8
Which patients under surveillance for colorectal cancer (CRC) after polyp removal need to continue having surveillance beyond the 1st surveillance colonoscopy (SC1)?
Our new analysis in Gut @BMJ.com examines which pt groups need ongoing surveillance.
gut.bmj.com/cgi/rapidpdf...
Which patients under surveillance for colorectal cancer (CRC) after polyp removal need to continue having surveillance beyond the 1st surveillance colonoscopy (SC1)?
Our new analysis in Gut @BMJ.com examines which pt groups need ongoing surveillance.
gut.bmj.com/cgi/rapidpdf...
April 7, 2025 at 9:30 AM
1/8
Which patients under surveillance for colorectal cancer (CRC) after polyp removal need to continue having surveillance beyond the 1st surveillance colonoscopy (SC1)?
Our new analysis in Gut @BMJ.com examines which pt groups need ongoing surveillance.
gut.bmj.com/cgi/rapidpdf...
Which patients under surveillance for colorectal cancer (CRC) after polyp removal need to continue having surveillance beyond the 1st surveillance colonoscopy (SC1)?
Our new analysis in Gut @BMJ.com examines which pt groups need ongoing surveillance.
gut.bmj.com/cgi/rapidpdf...
#CSPRGWeekOfResearch
Our data from @imperialcollegeldn.bsky.social PhD Emma Robbins is helping to develop the future of #ColorectalCancer screening guidelines
Women with low-risk distal polyps at flexi-sig screening were at 2x⬆️risk of proximal colon cancer compared to general population
Our data from @imperialcollegeldn.bsky.social PhD Emma Robbins is helping to develop the future of #ColorectalCancer screening guidelines
Women with low-risk distal polyps at flexi-sig screening were at 2x⬆️risk of proximal colon cancer compared to general population
March 20, 2025 at 4:29 PM
#CSPRGWeekOfResearch
Our data from @imperialcollegeldn.bsky.social PhD Emma Robbins is helping to develop the future of #ColorectalCancer screening guidelines
Women with low-risk distal polyps at flexi-sig screening were at 2x⬆️risk of proximal colon cancer compared to general population
Our data from @imperialcollegeldn.bsky.social PhD Emma Robbins is helping to develop the future of #ColorectalCancer screening guidelines
Women with low-risk distal polyps at flexi-sig screening were at 2x⬆️risk of proximal colon cancer compared to general population
Flexi-sig screening & colorectal cancer risk: Are we missing women at increased risk of proximal colon cancer?
Read our analysis of UKFSST data in @BMJ.com to discover if flexi-sig is sufficient to protect people with low-risk polyps
journals.sagepub.com/doi/10.1177/...
#CSPRGWeekOfResearch
Read our analysis of UKFSST data in @BMJ.com to discover if flexi-sig is sufficient to protect people with low-risk polyps
journals.sagepub.com/doi/10.1177/...
#CSPRGWeekOfResearch
March 20, 2025 at 4:04 PM
Flexi-sig screening & colorectal cancer risk: Are we missing women at increased risk of proximal colon cancer?
Read our analysis of UKFSST data in @BMJ.com to discover if flexi-sig is sufficient to protect people with low-risk polyps
journals.sagepub.com/doi/10.1177/...
#CSPRGWeekOfResearch
Read our analysis of UKFSST data in @BMJ.com to discover if flexi-sig is sufficient to protect people with low-risk polyps
journals.sagepub.com/doi/10.1177/...
#CSPRGWeekOfResearch
Our @CancerResearchUK.org & @NIHR.bsky.social funded work showed that quantitative data from serial FITs could predict ACN risk:
- No change in serial FIT results was associated with a ⬇️ ACN detection rate
- Serial increases were associated with⬆️ ACN detection rates
#CSPRGWeekOfResearch
- No change in serial FIT results was associated with a ⬇️ ACN detection rate
- Serial increases were associated with⬆️ ACN detection rates
#CSPRGWeekOfResearch
March 19, 2025 at 4:24 PM
Our @CancerResearchUK.org & @NIHR.bsky.social funded work showed that quantitative data from serial FITs could predict ACN risk:
- No change in serial FIT results was associated with a ⬇️ ACN detection rate
- Serial increases were associated with⬆️ ACN detection rates
#CSPRGWeekOfResearch
- No change in serial FIT results was associated with a ⬇️ ACN detection rate
- Serial increases were associated with⬆️ ACN detection rates
#CSPRGWeekOfResearch