Jake Stevens
immunojake.bsky.social
Jake Stevens
@immunojake.bsky.social
University of Cincinnati MD/PhD student, M4 | PhD in Immunology
Studying newborn immunity to viral pneumonia | Future Pediatrician-Scientist
Pinned
Really couldn't be more proud to have the last chapter of my PhD finally out in publication at @cellpress.bsky.social.

We looked at the mechanisms behind how the developing gut microbiota in newborns plays a role in education of the pulmonary immune response against respiratory viruses.
Really couldn't be more proud to have the last chapter of my PhD finally out in publication at @cellpress.bsky.social.

We looked at the mechanisms behind how the developing gut microbiota in newborns plays a role in education of the pulmonary immune response against respiratory viruses.
June 9, 2025 at 7:10 PM
That's all the new stuff for now! Excited to see how this platform works for scientific communication and continue updating as I finish up my MD/PhD and look forward to residency and beyond.
December 16, 2024 at 12:24 AM
And this is the second paper from my PhD, still in preprint, but hopefully out soon! We found a novel mechanism for T cell programming by the gut microbiota early in life important for protection against influenza. Some really cool mechanistic immunology and use of human data sets.
Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns
The immunological defects causing susceptibility to severe viral respiratory infections due to early-life dysbiosis remain ill-defined. Here, we show that influenza virus susceptibility in dysbiotic i...
www.biorxiv.org
December 16, 2024 at 12:23 AM
This was the first paper from my PhD, where we found that the gut microbiota programs pulmonary innate immune responses to bacterial pneumonia in non-human primates. It was a great look at unique neutrophil populations in the lungs important in early-life host defense!
The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota
Gut microbiota promote recovery from pneumonia by reinforcing the balance between homeostasis and inflammation in neonatal lungs.
www.science.org
December 16, 2024 at 12:19 AM
Here's a recap from finishing the PhD part of my MD/PhD! It was a great time in the Deshmukh Lab, learning about newborn pulmonary immune development.

Now over halfway through the 3rd year of medical school, it's been awesome seeing how scientific advances fit into clinical care.
December 16, 2024 at 12:15 AM
It won't really work well to transfer over everything from X, so I'll take this chance to start new!
December 16, 2024 at 12:13 AM
Intro:

Hi everyone! My name is Jake- MD/PhD student at UCCOM and Cincy Children's. PhD on how antibiotics affect newborn immune responses to pneumonia. Interested in peds-critical care. I love running and cycling- an attempt to outpace the many ups and downs of med/grad school. Moving over from X!
December 16, 2024 at 12:08 AM