Indrek Kalvet
@ikalvet.bsky.social
🇪🇪 De Novo enzyme design • HHMI Postdoc at the Institute for Protein Design at University of Washington
(oops, that is supposed to be a GIF, but it doesn't work on bsky...)
August 22, 2025 at 6:50 AM
(oops, that is supposed to be a GIF, but it doesn't work on bsky...)
PLACER played a valuable role in helping my colleagues Anna and @spellock.bsky.social design novel serine hydrolases from scratch:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Computational design of serine hydrolases
The design of enzymes with complex active sites that mediate multistep reactions remains an outstanding challenge. With serine hydrolases as a model system, we combined the generative capabilities of ...
www.science.org
February 13, 2025 at 8:28 PM
PLACER played a valuable role in helping my colleagues Anna and @spellock.bsky.social design novel serine hydrolases from scratch:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...